Challenges and opportunities for therapeutic targeting of calmodulin kinase II in heart D Nassal, D Gratz, TJ Hund Frontiers in pharmacology 11, 510022, 2020 | 53 | 2020 |
Protein Phosphatase 2A Regulates Cardiac Na+ Channels M El Refaey, H Musa, NP Murphy, ER Lubbers, M Skaf, M Han, O Cavus, ... Circulation research 124 (5), 737-746, 2019 | 44 | 2019 |
Calmodulin kinase II regulates atrial myocyte late sodium current, calcium handling, and atrial arrhythmia A Greer-Short, H Musa, KM Alsina, L Ni, TA Word, JO Reynolds, D Gratz, ... Heart rhythm 17 (3), 503-511, 2020 | 43 | 2020 |
MicroRNA biophysically modulates cardiac action potential by direct binding to ion channel D Yang, X Wan, AT Dennis, E Bektik, Z Wang, MGS Costa, C Fagnen, ... Circulation 143 (16), 1597-1613, 2021 | 39 | 2021 |
Ca2+/calmodulin-dependent kinase II-dependent regulation of atrial myocyte late Na+ current, Ca2+ cycling, and excitability: a mathematical modeling study B Onal, D Gratz, TJ Hund American Journal of Physiology-Heart and Circulatory Physiology 313 (6 …, 2017 | 33 | 2017 |
MICAL1 constrains cardiac stress responses and protects against disease by oxidizing CaMKII K Konstantinidis, VJ Bezzerides, L Lai, HM Isbell, AC Wei, Y Wu, ... The Journal of clinical investigation 130 (9), 4663-4678, 2020 | 29 | 2020 |
Synchronization of pacemaking in the sinoatrial node: a mathematical modeling study D Gratz, B Onal, A Dalic, TJ Hund Frontiers in Physics 6, 63, 2018 | 21 | 2018 |
Computational tools for automated histological image analysis and quantification in cardiac tissue D Gratz, AJ Winkle, A Dalic, SD Unudurthi, TJ Hund MethodsX 7, 100755, 2020 | 20 | 2020 |
βIV-Spectrin/STAT3 complex regulates fibroblast phenotype, fibrosis, and cardiac function NJ Patel, DM Nassal, AD Greer-Short, SD Unudurthi, BW Scandling, ... JCI insight 4 (20), 2019 | 18 | 2019 |
Emerging therapeutic targets for cardiac hypertrophy AJ Winkle, DM Nassal, R Shaheen, E Thomas, S Mohta, D Gratz, ... Expert opinion on therapeutic targets 26 (1), 29-40, 2022 | 17 | 2022 |
Defining new mechanistic roles for αii spectrin in cardiac function ER Lubbers, NP Murphy, H Musa, CYM Huang, R Gupta, MV Price, ... Journal of Biological Chemistry 294 (24), 9576-9591, 2019 | 16* | 2019 |
LongQt: A cardiac electrophysiology simulation platform B Onal, D Gratz, T Hund MethodsX 3, 589-599, 2016 | 15 | 2016 |
Emerging therapeutic targets for cardiac arrhythmias: Role of STAT3 in regulating cardiac fibroblast function NJ Patel, DM Nassal, D Gratz, TJ Hund Expert opinion on therapeutic targets 25 (1), 63-73, 2021 | 10 | 2021 |
Regulation of cardiac conduction and arrhythmias by ankyrin/spectrin-based macromolecular complexes D Nassal, J Yu, D Min, C Lane, R Shaheen, D Gratz, TJ Hund Journal of Cardiovascular Development and Disease 8 (5), 48, 2021 | 8 | 2021 |
Giant ankyrin-G regulates cardiac function O Cavus, J Williams, H Musa, M El Refaey, D Gratz, R Shaheen, ... Journal of Biological Chemistry 296, 2021 | 5 | 2021 |
Reverse translation: using computational modeling to enhance translational research D Gratz, TJ Hund, MJ Falvo, LE Wold Circulation research 122 (11), 1496-1498, 2018 | 2 | 2018 |
B-AB18-01 MICRO RNA BIOPHYSICALLY MODULATES CARDIAC ELECTROPHYSIOLOGY D Yang, X Wan, AT Dennis, E Bektik, Z Wang, MGS Costa, C Fagnen, ... Heart Rhythm 18 (8), S34-S35, 2021 | | 2021 |
Statistical Approach to Incorporating Experimental Variability into a Mathematical Model of the Voltage-Gated Na+ Channel and Human Atrial Action Potential D Gratz, AJ Winkle, SH Weinberg, TJ Hund Cells 10 (6), 1516, 2021 | | 2021 |
Modeling cardiomyocyte signaling pathways D Gratz, A Winkle, A Greer-Short, TJ Hund Modeling and Simulating Cardiac Electrical Activity, 5-1-5-22, 2020 | | 2020 |
TWEAK-Fn14 Axis: A Potential Therapeutic Target for Treating Heart Failure S Unudurthi, E Thomas, N Patel, A Winkle, D Gratz, T Hund Circulation Research 125 (Suppl_1), A229-A229, 2019 | | 2019 |