Stefan Günther

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Björn GrüningUniversity of FreiburgVerified email at informatik.uni-freiburg.de
Xavier LucasSenior scientist in computational drug design at Monte Rosa Therapeutics, BaselVerified email at monterosatx.com
Manfred JungInstitute of Pharmaceutical Sciences, University of Freiburg; former University of Münster, OttawaVerified email at pharmazie.uni-freiburg.de
Jan BieschkeUniversity College LondonVerified email at ucl.ac.uk
Dirk SchübelerDirector, Friedrich Miescher Institute for Biomedical Research, Basel, SwitzerlandVerified email at fmi.ch
Evangelia PetsalakiGroup Leader, EMBL-EBIVerified email at ebi.ac.uk
Reinhard SchneiderProf. Bioinformatics, University of Luxembourg, Head of Bioinformatics Core Facility, LuxembourgVerified email at uni.lu
Michael Kuhnresearch staff scientist & research coordinator in the lab of Peer Bork, EMBLVerified email at embl.de
Lars Juhl JensenUniversity of CopenhagenVerified email at cpr.ku.dk
Philip E. BourneUniversity of VirginiaVerified email at virginia.edu
Rob RussellProfessor of Protein Evolution, BioQuant/BZH, Heidelberg University, GermanyVerified email at bioquant.uni-heidelberg.de
Peer BorkDirector of EMBL HeidelbergVerified email at embl.de
Michael SchroederProfessor in Bioinformatics, TU DresdenVerified email at biotec.tu-dresden.de
Rolf BackofenProfessor für Bioinformatik, Universität FreiburgVerified email at informatik.uni-freiburg.de
Patrick MayGenome Analysis, Bioinformatics Core, Luxembourg Centre for Systems BiomedicineVerified email at uni.lu
Andreas HoppeLänderinstitut für Bienenkunde Hohen Neuendorf e.V.Verified email at dr-andreas-hoppe.de
Robert LehmannResearch Scientist - Living Systems Lab - KAUSTVerified email at kaust.edu.sa
Joern PielProfessor, ETH Zurich, Switzerland

Stefan Günther

Professor for Pharmaceutical Bioinformatics, Freiburg University

Verified email at pharmazie.uni-freiburg.de - Homepage

Bioinformatics


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SuperTarget and Matador: resources for exploring drug-target relationships S Günther, M Kuhn, M Dunkel, M Campillos, C Senger, E Petsalaki, ... Nucleic acids research 36 (suppl_1), D919-D922, 2007	707	2007
Small-molecule conversion of toxic oligomers to nontoxic β-sheet–rich amyloid fibrils J Bieschke, M Herbst, T Wiglenda, RP Friedrich, A Boeddrich, F Schiele, ... Nature chemical biology 8 (1), 93-101, 2012	493	2012
SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions S Preissner, K Kroll, M Dunkel, C Senger, G Goldsobel, D Kuzman, ... Nucleic acids research 38 (suppl_1), D237-D243, 2010	335	2010
Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease R Gilsbach, S Preissl, BA Grüning, T Schnick, L Burger, V Benes, A Würch, ... Nature communications 5 (1), 5288, 2014	328	2014
SuperPred: drug classification and target prediction M Dunkel, S Günther, J Ahmed, B Wittig, R Preissner Nucleic acids research 36 (suppl_2), W55-W59, 2008	182	2008
Legionella pneumophila induces IFNβ in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication B Opitz, M Vinzing, V van Laak, B Schmeck, G Heine, S Gunther, ... Journal of Biological Chemistry 281 (47), 36173-36179, 2006	172	2006
NAIP and Ipaf control Legionella pneumophila replication in human cells M Vinzing, J Eitel, J Lippmann, AC Hocke, J Zahlten, H Slevogt, ... The Journal of Immunology 180 (10), 6808-6815, 2008	166	2008
StreptomeDB: a resource for natural compounds isolated from Streptomyces species X Lucas, C Senger, A Erxleben, BA Grüning, K Döring, J Mosch, ... Nucleic acids research 41 (D1), D1130-D1136, 2012	151	2012
NANPDB: a resource for natural products from Northern African sources F Ntie-Kang, KK Telukunta, K Döring, CV Simoben, AF A. Moumbock, ... Journal of natural products 80 (7), 2067-2076, 2017	135	2017
4‐Acyl pyrroles: Mimicking acetylated lysines in histone code reading X Lucas, D Wohlwend, M Hügle, K Schmidtkunz, S Gerhardt, R Schüle, ... Angewandte Chemie International Edition 52 (52), 14055-14059, 2013	129	2013
Confocal multiview light-sheet microscopy G Medeiros, N Norlin, S Gunther, M Albert, L Panavaite, UM Fiuza, F Peri, ... Nature communications 6 (1), 8881, 2015	120	2015
Bromodomain drug discovery–the past, the present, and the future M Pervaiz, P Mishra, S Günther The Chemical Record 18 (12), 1808-1817, 2018	111	2018
StreptomeDB 2.0—an extended resource of natural products produced by streptomycetes D Klementz, K Doering, X Lucas, KK Telukunta, A Erxleben, D Deubel, ... Nucleic acids research 44 (D1), D509-D514, 2016	106	2016
Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function FA Hartl, E Beck-Garcìa, NM Woessner, LJ Flachsmann, RMHV Cárdenas, ... Nature immunology 21 (8), 902-913, 2020	97	2020
Regio-and stereoselective oxidative phenol coupling in Aspergillus niger CG Girol, KM Fisch, T Heinekamp, S Günther, W Hüttel, J Piel, ... Angew Chem Int Ed 51, 9788-9791, 2012	86	2012
Abietane diterpenes induce cytotoxic effects in human pancreatic cancer cell line MIA PaCa-2 through different modes of action M Fronza, E Lamy, S Günther, B Heinzmann, S Laufer, I Merfort Phytochemistry 78, 107-119, 2012	82	2012
StreptomeDB 3.0: an updated compendium of streptomycetes natural products AFA Moumbock, M Gao, A Qaseem, J Li, PA Kirchner, B Ndingkokhar, ... Nucleic acids research 49 (D1), D600-D604, 2021	79	2021
Regio- and Stereoselective Intermolecular Oxidative Phenol Coupling in Streptomyces A Präg, BA Grüning, M Häckh, S Lüdeke, M Wilde, A Luzhetskyy, ... Journal of the American Chemical Society 136 (17), 6195-6198, 2014	74	2014
Rational Design of an Aryl-C-Glycoside Catalyst from a Natural Product O-Glycosyltransferase J Härle, S Günther, B Lauinger, M Weber, B Kammerer, DL Zechel, ... Chemistry & Biology 18 (4), 520-530, 2011	72	2011
Docking without docking: ISEARCH—prediction of interactions using known interfaces S Günther, P May, A Hoppe, C Frömmel, R Preissner Proteins: Structure, Function, and Bioinformatics 69 (4), 839-844, 2007	69	2007

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