Harkness, T
Harkness, T
Professor, Biochemistry, Microbiology, and Immunology, University of Saskatchewan
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Cited by
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Elevated histone expression promotes life span extension
J Feser, D Truong, C Das, JJ Carson, J Kieft, T Harkness, JK Tyler
Molecular cell 39 (5), 724-735, 2010
Yeast histone H3 and H4 amino termini are important for nucleosome assembly in vivo and in vitro: redundant and position-independent functions in assembly but not in gene …
X Ling, TA Harkness, MC Schultz, G Fisher-Adams, M Grunstein
Genes & development 10 (6), 686-699, 1996
A crucial role of the mitochondrial protein import receptor MOM19 for the biogenesis of mitochondria
TA Harkness, FE Nargang, I van der Klei, W Neupert, R Lill
The Journal of cell biology 124 (5), 637-648, 1994
Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells
AA Goldberg, A Beach, GF Davies, TAA Harkness, A LeBlanc, ...
Oncotarget, 2011
Stimulation of the Mu A protein-mediated strand cleavage reaction by the Mu B protein, and the requirement of DNA nicking for stable type 1 transpososome formation. In vitro …
MG Surette, T Harkness, G Chaconas
Journal of Biological Chemistry 266 (5), 3118-3124, 1991
The yeast forkhead transcription factors fkh1 and fkh2 regulate lifespan and stress response together with the anaphase-promoting complex
SDL Postnikoff, ME Malo, B Wong, TAA Harkness
PLoS Genetics 8 (3), e1002583, 2012
A functional analysis reveals dependence on the anaphase-promoting complex for prolonged life span in yeast
TAA Harkness, KA Shea, C Legrand, M Brahmania, GF Davies
Genetics 168 (2), 759-774, 2004
Chromatin assembly in a yeast whole-cell extract
MC Schultz, DJ Hockman, TAA Harkness, WI Garinther, BA Altheim
Proceedings of the National Academy of Sciences 94 (17), 9034-9039, 1997
Ssd1 and Gcn2 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan
Z Hu, B Xia, SDL Postnikoff, ZJ Shen, AS Tomoiaga, TA Harkness, ...
Elife 7, e35551, 2018
Inactivation of the Neurospora crassa gene encoding the mitochondrial protein import receptor MOM19 by the technique of" sheltered RIP".
TA Harkness, RL MetZenberg, H Schneider, R Lill, W Neupert, ...
Genetics 136 (1), 107-118, 1994
Metformin inhibits the development, and promotes the resensitization, of treatment-resistant breast cancer
G Davies, L Lobanova, W Dawicki, G Groot, JR Gordon, M Bowen, ...
PloS one 12 (12), e0187191, 2017
Troglitazone reverses the multiple drug resistance phenotype in cancer cells
GF Davies, BHJ Juurlink, TAA Harkness
Drug design, development and therapy, 79-88, 2009
The Ubiquitin-Dependent Targeting Pathway in Saccharomyces cerevisiae Plays a Critical Role in Multiple Chromatin Assembly Regulatory Steps
TAA Harkness, GF Davies, V Ramaswamy, TG Arnason
Genetics 162 (2), 615-632, 2002
Development, maintenance, and reversal of multiple drug resistance: At the crossroads of TFPI1, ABC transporters, and HIF1α
T Arnason, T Harkness
Cancers 7 (4), 2063-2082, 2015
Regulation of Lysosomal Function by the DAF-16 Forkhead Transcription Factor Couples Reproduction to Aging in Caenorhabditis elegans
K Baxi, A Ghavidel, B Waddell, TA Harkness, CE de Carvalho
Genetics 207 (1), 83-101, 2017
Disruption of the nuclear gene encoding the 20.8-kDa subunit of NADH:ubiquinone reductase ofNeurospora mitochondria
MV da Silva, PC Alves, M Duarte, N Mota, A Lobo-da-Cunha, A Videira, ...
Molecular and General Genetics MGG 252, 177-183, 1996
Troglitazone overcomes doxorubicin-resistance in resistant K562 leukemia cells
GF Davies, WJ Roesler, BHJ Juurlink, TAA Harkness
Leukemia & lymphoma 46 (8), 1199-1206, 2005
Troglitazone inhibits histone deacetylase activity in breast cancer cells
GF Davies, AR Ross, TG Arnason, BHJ Juurlink, TAA Harkness
Cancer letters 288 (2), 236-250, 2010
A genome scale screen for mutants with delayed exit from mitosis: Ire1-independent induction of autophagy integrates ER homeostasis into mitotic lifespan
A Ghavidel, K Baxi, V Ignatchenko, M Prusinkiewicz, TG Arnason, ...
PLoS genetics 11 (8), e1005429, 2015
Novel Interaction between Apc5p and Rsp5p in an Intracellular Signaling Pathway in Saccharomyces cerevisiae
TG Arnason, MG Pisclevich, MD Dash, GF Davies, TAA Harkness
Eukaryotic cell 4 (1), 134-146, 2005
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