Follow
Nihar Kinarivala
Title
Cited by
Cited by
Year
Rational approaches, design strategies, structure activity relationship and mechanistic insights for therapeutic coumarin hybrids
H Singh, JV Singh, K Bhagat, HK Gulati, M Sanduja, N Kumar, ...
Bioorganic & medicinal chemistry 27 (16), 3477-3510, 2019
1002019
Synthesis and antineoplastic evaluation of mitochondrial complex II (succinate dehydrogenase) inhibitors derived from atpenin A5
H Wang, B Huwaimel, K Verma, J Miller, TM Germain, N Kinarivala, ...
ChemMedChem 12 (13), 1033-1044, 2017
572017
Engineering CAR-T cells to activate small-molecule drugs in situ
TJ Gardner, JP Lee, CM Bourne, D Wijewarnasuriya, N Kinarivala, ...
Nature chemical biology 18 (2), 216-225, 2022
492022
Discovery of aromatic carbamates that confer neuroprotective activity by enhancing autophagy and inducing the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2)
N Kinarivala, R Patel, RM Boustany, A Al-Ahmad, PC Trippier
Journal of medicinal chemistry 60 (23), 9739-9756, 2017
432017
Passage variation of PC12 cells results in inconsistent susceptibility to externally induced apoptosis
N Kinarivala, K Shah, TJ Abbruscato, PC Trippier
ACS chemical neuroscience 8 (1), 82-88, 2017
432017
Multi-targeting anticancer agents: Rational approaches, synthetic routes and structure activity relationship
H Singh, N Kinarivala, S Sharma
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2019
252019
Flupirtine derivatives as potential treatment for the neuronal ceroid lipofuscinoses
J Makoukji, F Saadeh, KA Mansour, S El‐Sitt, J Al Ali, N Kinarivala, ...
Annals of Clinical and Translational Neurology 5 (9), 1089-1103, 2018
252018
Progress in the Development of Small Molecule Therapeutics for the Treatment of Neuronal Ceroid Lipofuscinoses (NCLs) Miniperspective
N Kinarivala, PC Trippier
Journal of medicinal chemistry 59 (10), 4415-4427, 2016
222016
An iPSC-derived neuron model of CLN3 disease facilitates small molecule phenotypic screening
N Kinarivala, A Morsy, R Patel, AV Carmona, MS Sajib, S Raut, ...
ACS pharmacology & translational science 3 (5), 931-947, 2020
172020
Pharmacophore elucidation of phosphoiodyn A–Potent and selective peroxisome proliferator-activated receptor β/δ agonists with neuroprotective activity
N Kinarivala, JH Suh, M Botros, P Webb, PC Trippier
Bioorganic & Medicinal Chemistry Letters 26 (8), 1889-1893, 2016
152016
Rational approaches for the design of various GABA modulators and their clinical progression
K Bhagat, JV Singh, PP Pagare, N Kumar, A Sharma, G Kaur, ...
Molecular diversity 25, 551-601, 2021
142021
Discovery of first-in-class peptidomimetic neurolysin activators possessing enhanced brain penetration and stability
MS Rahman, S Kumari, SH Esfahani, S Nozohouri, S Jayaraman, ...
Journal of medicinal chemistry 64 (17), 12705-12722, 2021
112021
Exploration of relative chemoselectivity in the hydrodechlorination of 2-chloropyridines
N Kinarivala, PC Trippier
Tetrahedron letters 55 (39), 5386-5389, 2014
102014
Functional diversity of Gram-negative permeability barriers reflected in antibacterial activities and intracellular accumulation of antibiotics
IV Leus, J Adamiak, B Chandar, V Bonifay, S Zhao, SS Walker, ...
Antimicrobial Agents and Chemotherapy 67 (2), e01377-22, 2023
92023
Tailored quinolines demonstrate flexibility to exert antitumor effects through varied mechanisms-a medicinal perspective
S Sharma, A Singh, S Sharma, R Sharma, J Singh, N Kinarivala, K Nepali, ...
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2021
52021
Exogenous flupirtine as potential treatment for CLN3 disease
K Maalouf, J Makoukji, S Saab, NJ Makhoul, AV Carmona, N Kinarivala, ...
Cells 9 (8), 1872, 2020
52020
Gram-scale preparation of the antibiotic lead compound salicyl-AMS, a potent inhibitor of bacterial salicylate adenylation enzymes
N Kinarivala, LC Standke, T Guney, C Ji, N Noguchi, Y Asano, DS Tan
Methods in enzymology 638, 69-87, 2020
32020
Passage variation of PC12 cells results in inconsistent susceptibility to externally induced apoptosis. ACS Chem Neurosci. 2017; 8 (1): 82–8
N Kinarivala, K Shah, TJ Abbruscato, PC Trippier
2
Functionalized pyridine carbamates with enhanced neuroprotective activity
P Trippier, N Kinarivala, RM Boustany
US Patent 11,369,593, 2022
2022
Sex-specific Gene Expression in Flupirtine-Treated Cln3Δex7/8 Mouse Brain
J Makoukji, S Saab, K Maalouf, NJ Makhoul, AV Carmona, N Kinarivala, ...
Biochemistry & Pharmacology: Open Access 10, 2021
2021
The system can't perform the operation now. Try again later.
Articles 1–20