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Ryan Thwaites
Ryan Thwaites
Verified email at imperial.ac.uk
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Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study
AB Docherty, EM Harrison, CA Green, HE Hardwick, R Pius, L Norman, ...
bmj 369, 2020
33382020
Genetic mechanisms of critical illness in Covid-19
E Pairo-Castineira, S Clohisey, L Klaric, AD Bretherick, K Rawlik, D Pasko, ...
Nature 591 (7848), 92-98, 2021
13012021
Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score
SR Knight, A Ho, R Pius, I Buchan, G Carson, TM Drake, J Dunning, ...
bmj 370, 2020
10112020
SARS-CoV-2 Omicron-B. 1.1. 529 leads to widespread escape from neutralizing antibody responses
W Dejnirattisai, J Huo, D Zhou, J Zahradník, P Supasa, C Liu, ...
Cell 185 (3), 467-484. e15, 2022
9012022
Mapping the human genetic architecture of COVID-19
MEK Niemi, J Karjalainen, RG Liao, BM Neale, M Daly, A Ganna, ...
Nature 600, 472-477, 2021
716*2021
Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study
OV Swann, KA Holden, L Turtle, L Pollock, CJ Fairfield, TM Drake, S Seth, ...
bmj 370, 2020
7052020
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study
RA Evans, H McAuley, EM Harrison, A Shikotra, A Singapuri, M Sereno, ...
The Lancet Respiratory Medicine 9 (11), 1275-1287, 2021
4722021
Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study
RA Evans, OC Leavy, M Richardson, O Elneima, HJC McAuley, ...
The Lancet Respiratory Medicine 10 (8), 761-775, 2022
2842022
Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre …
CD Russell, CJ Fairfield, TM Drake, L Turtle, RA Seaton, DG Wootton, ...
The Lancet Microbe 2 (8), e354-e365, 2021
2782021
Cross-reactive memory T cells associate with protection against SARS-CoV-2 infection in COVID-19 contacts
R Kundu, JS Narean, L Wang, J Fenn, T Pillay, ND Fernandez, ...
Nature communications 13 (1), 80, 2022
2622022
Biomarkers for acute respiratory distress syndrome and prospects for personalised medicine
S Spadaro, M Park, C Turrini, T Tunstall, R Thwaites, T Mauri, R Ragazzi, ...
Journal of inflammation 16, 1-11, 2019
2322019
COVID‐19: Lessons from SARS and MERS
M Park, RS Thwaites, PJM Openshaw
European Journal of Immunology 50 (3), 308-311, 2020
2112020
Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study
RK Gupta, EM Harrison, A Ho, AB Docherty, SR Knight, M van Smeden, ...
The Lancet Respiratory Medicine 9 (4), 349-359, 2021
2072021
Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19
RS Thwaites, A Sanchez Sevilla Uruchurtu, MK Siggins, F Liew, ...
Science immunology 6 (57), eabg9873, 2021
1752021
Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the …
CI Bloom, TM Drake, AB Docherty, BJ Lipworth, SL Johnston, ...
The lancet Respiratory medicine 9 (7), 699-711, 2021
1642021
Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study
TM Drake, AM Riad, CJ Fairfield, C Egan, SR Knight, R Pius, ...
The Lancet 398 (10296), 223-237, 2021
1422021
A prenylated dsRNA sensor protects against severe COVID-19
A Wickenhagen, E Sugrue, S Lytras, S Kuchi, M Noerenberg, ML Turnbull, ...
Science 374 (6567), eabj3624, 2021
1412021
Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza.
J Dunning, S Blankley, LT Hoang, M Cox, CM Graham, PL James, ...
Nature immunology 19 (6), 625, 2018
1332018
Outcomes of COVID-19 related hospitalization among people with HIV in the ISARIC WHO Clinical Characterization Protocol (UK): a prospective observational study
AM Geretti, AJ Stockdale, SH Kelly, M Cevik, S Collins, L Waters, G Villa, ...
Clinical Infectious Diseases, 2020
1272020
Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection
MS Habibi, RS Thwaites, M Chang, A Jozwik, A Paras, F Kirsebom, ...
Science 370 (6513), eaba9301, 2020
1152020
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