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Chao Gao
Chao Gao
Verified email at amc.edu
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Year
CRISPR/Cas9 facilitates investigation of neural circuit disease using human iPSCs: mechanism of epilepsy caused by an SCN1A loss-of-function mutation
J Liu, C Gao, W Chen, W Ma, X Li, Y Shi, H Zhang, L Zhang, Y Long, H Xu, ...
Translational psychiatry 6 (1), e703-e703, 2016
1002016
Loss of histone H3 K79 methyltransferase Dot1l facilitates kidney fibrosis by upregulating endothelin 1 through histone deacetylase 2
L Zhang, L Chen, C Gao, E Chen, AR Lightle, L Foulke, B Zhao, ...
Journal of the American Society of Nephrology 31 (2), 337-349, 2020
382020
Novel role of TRPV2 in promoting the cytotoxicity of H2O2-mediated oxidative stress in human hepatoma cells
W Ma, C Li, S Yin, J Liu, C Gao, Z Lin, R Huang, J Huang, Z Li
Free Radical Biology and Medicine 89, 1003-1013, 2015
312015
AQP2: Mutations associated with congenital nephrogenic diabetes insipidus and regulation by post-translational modifications and protein-protein interactions
C Gao, PJ Higgins, W Zhang
Cells 9 (10), 2172, 2020
272020
Aldosterone-regulated sodium transport and blood pressure
A Tsilosani, C Gao, W Zhang
Frontiers in Physiology 13, 770375, 2022
262022
Urinary AQP5 is independently associated with eGFR decline in patients with type 2 diabetes and nephropathy
C Gao, W Zhang
Diabetes research and clinical practice 155, 107805, 2019
182019
Heat shock protein 27, a novel downstream target of collagen type XI alpha 1, synergizes with fatty acid oxidation to confer cisplatin resistance in ovarian cancer cells
JP Heiserman, S Nallanthighal, CC Gifford, K Graham, R Samarakoon, ...
Cancers 13 (19), 4855, 2021
142021
Generation of distal renal segments involves a unique population of Aqp2+ progenitor cells
C Gao, L Chen, E Chen, A Tsilosani, Y Xia, W Zhang
Journal of the American Society of Nephrology 32 (12), 3035-3049, 2021
132021
Insights into cellular and molecular basis for urinary tract infection in autosomal-dominant polycystic kidney disease
C Gao, L Zhang, Y Zhang, DP Wallace, RI Lopez-Soler, PJ Higgins, ...
American Journal of Physiology-Renal Physiology 313 (5), F1077-F1083, 2017
122017
Roles of the lateral fenestration residues of the P2X4 receptor that contribute to the channel function and the deactivation effect of ivermectin
C Gao, Q Yu, H Xu, L Zhang, J Liu, Y Jie, W Ma, DSK Samways, Z Li
Purinergic Signalling 11, 229-238, 2015
122015
Highly tamoxifen-inducible principal cell-specific Cre mice with complete fidelity in cell specificity and no leakiness
L Chen, C Gao, L Zhang, Y Zhang, E Chen, W Zhang
American Journal of Physiology-Renal Physiology 314 (4), F572-F583, 2018
112018
Involvement of ectodomain Leu 214 in ATP binding and channel desensitization of the P2X4 receptor
L Zhang, H Xu, Y Jie, C Gao, W Chen, S Yin, DSK Samways, Z Li
Biochemistry 53 (18), 3012-3019, 2014
112014
Aqp2+ Progenitor Cells Maintain and Repair Distal Renal Segments
C Gao, L Zhang, E Chen, W Zhang
Journal of the American Society of Nephrology, 2022
72022
Involvement of the left-flipper-to-dorsal-fin interface of the zebrafish P2X4 receptor in ATP binding and structural rearrangement
Y Jie, L Zhang, H Xu, C Gao, W Ma, Z Li
Neuroscience Letters 582, 1-5, 2014
62014
Potential renal stem/progenitor cells identified by in vivo lineage tracing
W Zhang, C Gao, A Tsilosani, R Samarakoon, R Plews, PJ Higgins
American Journal of Physiology-Renal Physiology 322 (4), F379-F391, 2022
32022
Pkd2 Deficiency in Embryonic Aqp2+ Progenitor Cells Is Sufficient to Cause Severe Polycystic Kidney Disease
A Tsilosani, C Gao, E Chen, AR Lightle, S Shehzad, M Sharma, PV Tran, ...
Journal of the American Society of Nephrology, 10.1681, 2024
22024
Pkd2 Deficiency in Embryonic Aqp2+ Progenitor Cells Is Sufficient to Cause Severe Polycystic Kidney Disease: FR-PO569
A Tsilosani, C Gao, SA Shehzad, E Chen, M Sharma, PV Tran, CM Bates, ...
Journal of the American Society of Nephrology 34 (11S), 560, 2023
2023
Basic Research
A Tsilosani, C Gao, E Chen, AR Lightle, S Shehzad, M Sharma, PV Tran, ...
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