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Jacob Schwarz
Jacob Schwarz
Biophysics Researcher
Verified email at umn.edu
Title
Cited by
Cited by
Year
Fluorescence dynamics of a FRET probe designed for crowding studies
M Currie, H Leopold, J Schwarz, AJ Boersma, ED Sheets, AA Heikal
The Journal of Physical Chemistry B 121 (23), 5688-5698, 2017
372017
Crowding effects on energy-transfer efficiencies of hetero-FRET probes as measured using time-resolved fluorescence anisotropy
HJ Leopold, R Leighton, J Schwarz, AJ Boersma, ED Sheets, AA Heikal
The Journal of Physical Chemistry B 123 (2), 379-393, 2018
232018
Macromolecular crowding effects on energy transfer efficiency and donor-acceptor distance of hetero-FRET sensors using time-resolved fluorescence
J Schwarz, HJ Leopold, R Leighton, RC Miller, CP Aplin, AJ Boersma, ...
Methods and applications in fluorescence 7 (2), 025002, 2019
192019
Cardiac ryanodine receptor N-terminal region biosensors identify novel inhibitors via FRET-based high-throughput screening
J Zhang, DP Singh, CY Ko, R Nikolaienko, SMWK Yuen, JA Schwarz, ...
Journal of Biological Chemistry 298 (1), 2022
62022
Kinetics model for the wavelength-dependence of excited-state dynamics of hetero-FRET sensors
J Schwarz, R Leighton, HJ Leopold, M Currie, AJ Boersma, ED Sheets, ...
Ultrafast Nonlinear Imaging and Spectroscopy V 10380, 73-84, 2017
62017
RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET
J Seflova, JA Schwarz, AN Smith, B Svensson, DJ Blackwell, TA Phillips, ...
ACS Chemical Biology 18 (10), 2290-2299, 2023
22023
Monitoring Macromolecular Crowding via FRET using Wavelength-Dependent Fluorescence Lifetime Measurements
J Schwarz, M Currie, H Leopold, AJ Boersma, AA Heikal, ED Sheets
Biophysical Journal 112 (3), 347a, 2017
12017
Macromolecular crowding effects on the excited-state dynamics of novel FRET probes using time-resolved fluorescence
J Schwarz
12017
ent-Verticilide B1 inhibits type 2 ryanodine receptor channels and is antiarrhythmic in Casq2-/-mice
A Gochman, TQ Do, K Kim, J Schwarz, MP Thorpe, D Blackwell, AN Smith, ...
Biophysical Journal 123 (3), 105a, 2024
2024
Insight into the therapeutic potential of ent-verticilide based on direct measures of RyR function
JA Schwarz, D Blackwell, AN Smith, RT Rebbeck, JN Johnston, ...
Biophysical Journal 121 (3), 377a, 2022
2022
Understanding calmodulin regulation of RyR1 through steady state and stopped-flow fluorescence detection of Ca2+ binding kinetics to calmodulin bound to purified full-length RyR1
J Zhang, MR McCarthy, LM Treinen, S Mast, JA Schwarz, DD Thomas, ...
Biophysical Journal 121 (3), 379a-380a, 2022
2022
FRET assays for RyR-targeted drug discovery platforms
RT Rebbeck, K Berg, GM Evans, J Schwarz, JR Trask, LM McGurran, ...
Biophysical Journal 121 (3), 174a, 2022
2022
High-Throughput Screening and Drug Development to Fix RyR Pathology
RT Rebbeck, K Rozman, GM Evans, J Schwarz, M Baran, CC Aldrich, ...
Biophysical Journal 120 (3), 148a-149a, 2021
2021
Cardiac RyR N-terminal region biosensors for FRET-based high-throughput screening
J Zhang, SM Wong King Yuen, JA Schwarz, LM Treinen, CC Tung, ...
bioRxiv, 2021.02. 07.430153, 2021
2021
High-Throughput Screening Yields Allosteric Inhibitors of Leaky RyRs for Therapeutic Development
RT Rebbeck, GM Evans, K Rozman, JA Schwarz, MC Wold, M Baran, ...
Biophysical Journal 118 (3), 568a, 2020
2020
Elucidating the flexibility effects on the hydrodynamic volume of hetero-FRET probes using fluorescence correlation spectroscopy and time-resolved fluorescence anisotropy
N Anye, H Leopold, HB Lee, J Schwarz, E Sheets, A Heikal
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018
2018
Modeling the Rotational Dynamics of Novel Hetero-FRET Probes as Measured using Time-Resolved Anisotropy
RE Leighton, H Leopold, J Schwarz, AJ Boersma, ED Sheets, AA Heikal
Biophysical Journal 114 (3), 341a-342a, 2018
2018
Characterization of a Novel FRET Probe in a Crowded Environment using Time-Resolved Anisotropy
H Leopold, M Currie, J Schwarz, AJ Boersma, ED Sheets, AA Heikal
Biophysical Journal 112 (3), 346a, 2017
2017
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