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Chunyu Zhao
Chunyu Zhao
Verified email at emory.edu
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Year
Amyloid fibril structure of α-synuclein determined by cryo-electron microscopy
Y Li, C Zhao, F Luo, Z Liu, X Gui, Z Luo, X Zhang, D Li, C Liu, X Li
Cell research 28 (9), 897-903, 2018
3942018
Parkinson’s disease-related phosphorylation at Tyr39 rearranges α-synuclein amyloid fibril structure revealed by cryo-EM
K Zhao, YJ Lim, Z Liu, H Long, Y Sun, JJ Hu, C Zhao, Y Tao, X Zhang, ...
Proceedings of the National Academy of Sciences 117 (33), 20305-20315, 2020
1382020
Versatile structures of α-synuclein
C Wang, C Zhao, D Li, Z Tian, Y Lai, J Diao, C Liu
Frontiers in molecular neuroscience 9, 48, 2016
1222016
Hsp27 chaperones FUS phase separation under the modulation of stress-induced phosphorylation
Z Liu, S Zhang, J Gu, Y Tong, Y Li, X Gui, H Long, C Wang, C Zhao, J Lu, ...
Nature structural & molecular biology 27 (4), 363-372, 2020
1202020
Parkinson’s disease associated mutation E46K of α-synuclein triggers the formation of a distinct fibril structure
K Zhao, Y Li, Z Liu, H Long, C Zhao, F Luo, Y Sun, Y Tao, X Su, D Li, X Li, ...
Nature communications 11 (1), 2643, 2020
1022020
Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease
S Zhang, YQ Liu, C Jia, YJ Lim, G Feng, E Xu, H Long, Y Kimura, Y Tao, ...
Proceedings of the National Academy of Sciences 118 (26), e2011196118, 2021
702021
N-terminal acetylation preserves α-synuclein from oligomerization by blocking intermolecular hydrogen bonds
B Bu, X Tong, D Li, Y Hu, W He, C Zhao, R Hu, X Li, Y Shao, C Liu, ...
ACS chemical neuroscience 8 (10), 2145-2151, 2017
582017
Mechanistic insights into the switch of αB-crystallin chaperone activity and self-multimerization
Z Liu, C Wang, Y Li, C Zhao, T Li, D Li, S Zhang, C Liu
Journal of Biological Chemistry 293 (38), 14880-14890, 2018
452018
Detecting Single‐Molecule Dynamics on Lipid Membranes with Quenchers‐in‐a‐Liposome FRET
DF Ma, CH Xu, WQ Hou, CY Zhao, JB Ma, XY Huang, Q Jia, L Ma, J Diao, ...
Angewandte Chemie International Edition 58 (17), 5577-5581, 2019
252019
Heat shock protein 104 (HSP104) chaperones soluble Tau via a mechanism distinct from its disaggregase activity
X Zhang, S Zhang, L Zhang, J Lu, C Zhao, F Luo, D Li, X Li, C Liu
Journal of Biological Chemistry 294 (13), 4956-4965, 2019
212019
Assessment of cholesterol homeostasis in the living human brain
A Haider, C Zhao, L Wang, Z Xiao, J Rong, X Xia, Z Chen, SK Pfister, ...
Science translational medicine 14 (665), eadc9967, 2022
172022
Novel reversible-binding PET ligands for imaging monoacylglycerol lipase based on the piperazinyl azetidine scaffold
J Rong, W Mori, X Xia, MA Schafroth, C Zhao, RS Van, T Yamasaki, ...
Journal of medicinal chemistry 64 (19), 14283-14298, 2021
92021
Discovery of a highly specific 18F-labeled PET ligand for phosphodiesterase 10A enabled by novel spirocyclic iodonium ylide radiofluorination
Z Xiao, H Wei, Y Xu, A Haider, J Wei, S Yuan, J Rong, C Zhao, G Li, ...
Acta Pharmaceutica Sinica B 12 (4), 1963-1975, 2022
72022
Structure–activity relationship of pyrazol-4-yl-pyridine derivatives and identification of a radiofluorinated probe for imaging the muscarinic acetylcholine receptor M4
A Haider, X Deng, O Mastromihalis, SK Pfister, TE Jeppesen, Z Xiao, ...
Acta Pharmaceutica Sinica B 13 (1), 213-226, 2023
52023
Development of a triazolobenzodiazepine-based PET probe for subtype-selective vasopressin 1A receptor imaging
A Haider, Z Xiao, X Xia, J Chen, RS Van, S Kuang, C Zhao, J Rong, ...
Pharmacological research 173, 105886, 2021
52021
Imaging of transmembrane AMPA receptor regulatory proteins by positron emission tomography
Q Yu, K Kumata, J Rong, Z Chen, T Yamasaki, J Chen, Z Xiao, H Ishii, ...
Journal of medicinal chemistry 65 (13), 9144-9158, 2022
42022
Parkinson’s disease associated mutation E46K of α-synuclein triggers the formation of a novel fibril structure
K Zhao, Y Li, Z Liu, H Long, C Zhao, F Luo, Y Sun, Y Tao, X Su, D Li, X Li, ...
bioRxiv, 870758, 2019
32019
Evaluation of [18F]RoSMA-18-d6 as a CB2 PET Radioligand in Nonhuman Primates
A Haider, L Wang, L Gobbi, Y Li, A Chaudhary, X Zhou, J Chen, C Zhao, ...
ACS chemical neuroscience 14 (20), 3752-3760, 2023
22023
Investigation of structure and dynamics of alpha-synuclein on membrane by quenchers-in-a-liposome fluorescence resonance energy transfer method
M Dong-Fei, H Wen-Qing, X Chun-Hua, Z Chun-Yu, M Jian-Bing, ...
ACTA PHYSICA SINICA 69 (3), 2020
22020
Synthesis and Biological Evaluation of Enantiomerically Pure (R)- and (S)-[18F]OF-NB1 for Imaging the GluN2B Subunit-Containing NMDA Receptors
M Korff, A Chaudhary, Y Li, X Zhou, C Zhao, J Rong, J Chen, Z Xiao, ...
Journal of Medicinal Chemistry 66 (23), 16018-16031, 2023
12023
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