N6-Methyladenosine: a conformational marker that regulates the substrate specificity of human demethylases FTO and ALKBH5 S Zou, JDW Toh, KHQ Wong, YG Gao, W Hong, ECY Woon Scientific reports 6 (1), 25677, 2016 | 151 | 2016 |
A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N 6-methyladenosine demethylase FTO JDW Toh, L Sun, LZM Lau, J Tan, JJA Low, CWQ Tang, EJY Cheong, ... Chemical science 6 (1), 112-122, 2015 | 104 | 2015 |
Single-nucleotide-resolution sequencing of human N6-methyldeoxyadenosine reveals strand-asymmetric clusters associated with SSBP1 on the mitochondrial … CWQ Koh, YT Goh, JDW Toh, SP Neo, SB Ng, J Gunaratne, YG Gao, ... Nucleic acids research 46 (22), 11659-11670, 2018 | 71 | 2018 |
Distinct RNA N-demethylation pathways catalyzed by nonheme iron ALKBH5 and FTO enzymes enable regulation of formaldehyde release rates JDW Toh, SWM Crossley, KJ Bruemmer, EJ Ge, D He, DA Iovan, ... Proceedings of the National Academy of Sciences 117 (41), 25284-25292, 2020 | 54 | 2020 |
Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization Y Xie, J Sun, X Han, A Turšić-Wunder, JDW Toh, W Hong, YG Gao, ... Nature communications 10 (1), 5078, 2019 | 39 | 2019 |
Purification‐Free, Small‐Scale Synthesis of Isothiocyanates by Reagentless Fragmentation of Polymer‐Supported 1, 4, 2‐Oxathiazoles BA Burkett, P Fu, RJ Hewitt, SL Ng, JDW Toh European Journal of Organic Chemistry 2014 (5), 1053-1058, 2014 | 13 | 2014 |
Formaldehyde regulates S-adenosylmethionine biosynthesis and one-carbon metabolism VN Pham, KJ Bruemmer, JDW Toh, EJ Ge, L Tenney, CC Ward, ... Science 382 (6670), eabp9201, 2023 | 12 | 2023 |
The unusual di‐domain structure of Dunaliella salina glycerol‐3‐phosphate dehydrogenase enables direct conversion of dihydroxyacetone phosphate to glycerol Q He, JD Toh, R Ero, Z Qiao, V Kumar, A Serra, J Tan, SK Sze, YG Gao The Plant Journal 102 (1), 153-164, 2020 | 12 | 2020 |
Antiobesity effects of natural products from an epigenetic perspective ECY Woon, JDW Toh Studies in Natural Products Chemistry 41, 161-193, 2014 | 6 | 2014 |
Abstract LB033: Identification of small molecule Pan-TEAD inhibitors disrupting YAP-TEAD protein-protein interaction and targeting gastric cancer cells R Kumar, J Toh, J Thian, NF Mohideen, J Sun, S Chakraborty, ... Cancer Research 84 (7_Supplement), LB033-LB033, 2024 | | 2024 |
TEAD TARGETING COMPOUNDS AND METHODS THEREOF JDW Toh, W Hong, R Kumar | | 2023 |