Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis T Yan, Y Luo, N Yan, K Hamada, N Zhao, Y Xia, P Wang, C Zhao, D Qi, ... Hepatology 77 (1), 239-255, 2023 | 43 | 2023 |
Development of three-dimensional cell culture scaffolds using laminin peptide-conjugated agarose microgels Y Yamada, C Yoshida, K Hamada, Y Kikkawa, M Nomizu Biomacromolecules 21 (9), 3765-3771, 2020 | 32 | 2020 |
New negamycin-based potent readthrough derivative effective against TGA-type nonsense mutations K Hamada, N Omura, A Taguchi, A Baradaran-Heravi, M Kotake, M Arai, ... ACS medicinal chemistry letters 10 (10), 1450-1456, 2019 | 24 | 2019 |
3-Nitro-2-pyridinesulfenyl-mediated solid-phase disulfide ligation in the synthesis of disulfide bond-containing cyclic peptides A Taguchi, K Fukumoto, Y Asahina, A Kajiyama, S Shimura, K Hamada, ... Organic & Biomolecular Chemistry 13 (11), 3186-3189, 2015 | 23 | 2015 |
Discovery of Natural Products Possessing Selective Eukaryotic Readthrough Activity: 3‐epi‐Deoxynegamycin and Its Leucine Adduct A Taguchi, K Hamada, M Kotake, M Shiozuka, H Nakaminami, T Pillaiyar, ... ChemMedChem 9 (10), 2233-2237, 2014 | 20 | 2014 |
Chemotherapeutics overcoming nonsense mutation-associated genetic diseases: medicinal chemistry of negamycin A Taguchi, K Hamada, Y Hayashi The Journal of antibiotics 71 (2), 205-214, 2018 | 18 | 2018 |
Crosstalk between CYP2E1 and PPARα substrates and agonists modulate adipose browning and obesity Y Zhang, T Yan, T Wang, X Liu, K Hamada, D Sun, Y Sun, Y Yang, ... Acta Pharmaceutica Sinica B 12 (5), 2224-2238, 2022 | 13 | 2022 |
St. John’s Wort alleviates dextran sodium sulfate-induced colitis through pregnane X receptor-dependent NFκB antagonism T Yan, Y Luo, Y Xia, K Hamada, Q Wang, N Yan, KW Krausz, JM Ward, ... FASEB journal: official publication of the Federation of American Societies …, 2021 | 12 | 2021 |
Alpha-dystroglycan binding peptide A2G80-modified stealth liposomes as a muscle-targeting carrier for Duchenne muscular dystrophy E Sasaki, Y Hayashi, Y Kimura, S Sashida, N Hamano, K Nirasawa, ... Journal of controlled release 329, 1037-1045, 2021 | 11 | 2021 |
Characterization of dystroglycan binding in adhesion of human induced pluripotent stem cells to laminin-511 E8 fragment Y Sugawara, K Hamada, Y Yamada, J Kumai, M Kanagawa, K Kobayashi, ... Scientific Reports 9 (1), 13037, 2019 | 11 | 2019 |
Withaferin A in the treatment of liver diseases: progress and pharmacokinetic insights Y Xia, M Yan, P Wang, K Hamada, N Yan, H Hao, FJ Gonzalez, T Yan Drug Metabolism and Disposition 50 (5), 685-693, 2022 | 10 | 2022 |
Withaferin A alleviates ethanol-induced liver injury by inhibiting hepatic lipogenesis K Hamada, P Wang, Y Xia, N Yan, S Takahashi, KW Krausz, H Hao, ... Food and Chemical Toxicology 160, 112807, 2022 | 10 | 2022 |
Structure–Activity Relationship Study of Leucyl-3-epi-deoxynegamycin for Potent Premature Termination Codon Readthrough A Taguchi, K Hamada, M Shiozuka, M Kobayashi, S Murakami, ... ACS Medicinal Chemistry Letters 8 (10), 1060-1065, 2017 | 10 | 2017 |
Structure–Activity Relationship Studies of 3-epi-Deoxynegamycin Derivatives as Potent Readthrough Drug Candidates K Hamada, A Taguchi, M Kotake, S Aita, S Murakami, K Takayama, ... ACS Medicinal Chemistry Letters 6 (6), 689-694, 2015 | 10 | 2015 |
Structure–activity relationships of RGD-containing peptides in integrin αvβ5-mediated cell adhesion Y Yamada, T Onda, Y Wada, K Hamada, Y Kikkawa, M Nomizu ACS omega 8 (5), 4687-4693, 2023 | 9 | 2023 |
Synthesis and structure–activity relationship study of FD-891: importance of the side chain and C8–C9 epoxide for cytotoxic activity against cancer cells T Itagaki, A Kawamata, M Takeuchi, K Hamada, Y Iwabuchi, T Eguchi, ... The Journal of Antibiotics 69 (4), 287-293, 2016 | 8 | 2016 |
Identification of active sequences in human laminin α5 G domain J Kumai, Y Yamada, K Hamada, F Katagiri, K Hozumi, Y Kikkawa, ... Journal of Peptide Science 25 (12), e3218, 2019 | 7 | 2019 |
Laminin β2 variants associated with isolated nephropathy that impact matrix regulation Y Kikkawa, T Hashimoto, K Takizawa, S Urae, H Masuda, M Matsunuma, ... JCI insight 6 (6), 2021 | 6 | 2021 |
Evaluation of extracellular matrix mimetic laminin bioactive peptide and elastin‐like polypeptide AT Truong, K Hamada, Y Yamada, H Guo, Y Kikkawa, CT Okamoto, ... The FASEB Journal 34 (5), 6729-6740, 2020 | 6 | 2020 |
Development of a bispecific DNA-aptamer-based lysosome-targeting chimera for HER2 protein degradation K Hamada, T Hashimoto, R Iwashita, Y Yamada, Y Kikkawa, M Nomizu Cell Reports Physical Science 4 (3), 2023 | 5 | 2023 |