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Jiandong Huo
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SARS-CoV-2 Omicron-B. 1.1. 529 leads to widespread escape from neutralizing antibody responses
W Dejnirattisai, J Huo, D Zhou, J Zahradník, P Supasa, C Liu, ...
Cell 185 (3), 467-484. e15, 2022
9212022
Antibody escape of SARS-CoV-2 Omicron BA. 4 and BA. 5 from vaccine and BA. 1 serum
A Tuekprakhon, R Nutalai, A Dijokaite-Guraliuc, D Zhou, HM Ginn, ...
Cell 185 (14), 2422-2433. e13, 2022
5762022
Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2
J Huo, A Le Bas, RR Ruza, HME Duyvesteyn, H Mikolajek, T Malinauskas, ...
Nature structural & molecular biology 27 (9), 846-854, 2020
4732020
Neutralization of SARS-CoV-2 by destruction of the prefusion spike
J Huo, Y Zhao, J Ren, D Zhou, HME Duyvesteyn, HM Ginn, L Carrique, ...
Cell host & microbe 28 (3), 445-454. e6, 2020
3672020
Structure and interactions of the human programmed cell death 1 receptor
X Cheng, V Veverka, A Radhakrishnan, LC Waters, FW Muskett, ...
Journal of Biological Chemistry 288 (17), 11771-11785, 2013
3512013
Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient
D Zhou, HME Duyvesteyn, CP Chen, CG Huang, TH Chen, SR Shih, ...
Nature structural & molecular biology 27 (10), 950-958, 2020
2872020
A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses
TK Tan, P Rijal, R Rahikainen, AH Keeble, L Schimanski, S Hussain, ...
Nature communications 12 (1), 542, 2021
2332021
Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19
SP Graham, RK McLean, AJ Spencer, S Belij-Rammerstorfer, D Wright, ...
NPJ vaccines 5 (1), 69, 2020
1492020
Recurrent activating mutations of CD28 in peripheral T-cell lymphomas
J Rohr, S Guo, J Huo, A Bouska, C Lachel, Y Li, PD Simone, W Zhang, ...
Leukemia 30 (5), 1062-1070, 2016
1292016
Potent cross-reactive antibodies following Omicron breakthrough in vaccinees
R Nutalai, D Zhou, A Tuekprakhon, HM Ginn, P Supasa, C Liu, J Huo, ...
Cell 185 (12), 2116-2131. e18, 2022
1162022
A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19
J Huo, H Mikolajek, A Le Bas, JJ Clark, P Sharma, A Kipar, J Dormon, ...
Nature communications 12 (1), 5469, 2021
1092021
Differences in CD80 and CD86 transendocytosis reveal CD86 as a key target for CTLA-4 immune regulation
A Kennedy, E Waters, B Rowshanravan, C Hinze, C Williams, D Janman, ...
Nature immunology 23 (9), 1365-1378, 2022
842022
Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions
P Jönsson, JH Southcombe, AM Santos, J Huo, RA Fernandes, J McColl, ...
Proceedings of the National Academy of Sciences 113 (20), 5682-5687, 2016
662016
A haemagglutination test for rapid detection of antibodies to SARS-CoV-2
A Townsend, P Rijal, J Xiao, TK Tan, KYA Huang, L Schimanski, J Huo, ...
Nature communications 12 (1), 1951, 2021
622021
Structural basis of antifolate recognition and transport by PCFT
JL Parker, JC Deme, G Kuteyi, Z Wu, J Huo, ID Goldman, RJ Owens, ...
Nature 595 (7865), 130-134, 2021
482021
A delicate balance between antibody evasion and ACE2 affinity for Omicron BA. 2.75
J Huo, A Dijokaite-Guraliuc, C Liu, D Zhou, HM Ginn, R Das, P Supasa, ...
Cell reports 42 (1), 2023
382023
Cryo-EM structure of PepT2 reveals structural basis for proton-coupled peptide and prodrug transport in mammals
JL Parker, JC Deme, Z Wu, G Kuteyi, J Huo, RJ Owens, PC Biggin, ...
Science advances 7 (35), eabh3355, 2021
352021
Further antibody escape by Omicron BA. 4 and BA. 5 from vaccine and BA. 1 serum
A Tuekprakhon, J Huo, R Nutalai, A Dijokaite-Guraliuc, D Zhou, HM Ginn, ...
bioRxiv, 2022.05. 21.492554, 2022
322022
Architecture of cell–cell junctions in situ reveals a mechanism for bacterial biofilm inhibition
CE Melia, JR Bolla, S Katharios-Lanwermeyer, DB Mihaylov, ...
Proceedings of the National Academy of Sciences 118 (31), e2109940118, 2021
312021
SARS-CoV-2 triggers pericyte-mediated cerebral capillary constriction
C Hirunpattarasilp, G James, J Kwanthongdee, F Freitas, J Huo, H Sethi, ...
Brain 146 (2), 727-738, 2023
302023
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