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Sinto Sebastian Chirackal
Sinto Sebastian Chirackal
Research Scientist, Mayo Clinic
Verified email at mayo.edu
Title
Cited by
Cited by
Year
The complexity of targeting EGFR signalling in cancer: from expression to turnover
S Sebastian, J Settleman, SJ Reshkin, A Azzariti, A Bellizzi, A Paradiso
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1766 (1), 120-139, 2006
3962006
p53 haploinsufficiency and functional abnormalities in multiple myeloma
PJ Teoh, TH Chung, S Sebastian, SN Choo, J Yan, SB Ng, R Fonseca, ...
Leukemia 28 (10), 2066-2074, 2014
902014
Aurora B kinase inhibitor AZD1152: determinants of action and ability to enhance chemotherapeutics effectiveness in pancreatic and colon cancer
A Azzariti, G Bocci, L Porcelli, A Fioravanti, P Sini, GM Simone, ...
British journal of cancer 104 (5), 769-780, 2011
782011
Tumor-associated macrophages and extracellular matrix metalloproteinase inducer in prognosis of multiple myeloma
S Panchabhai, K Kelemen, G Ahmann, S Sebastian, J Mantei, R Fonseca
Leukemia 30 (4), 951-954, 2016
652016
Co‐expression of CD133+/CD44+ in human colon cancer and liver metastasis
A Bellizzi, S Sebastian, P Ceglia, M Centonze, R Divella, EF Manzillo, ...
Journal of cellular physiology 228 (2), 408-415, 2013
622013
Multiple myeloma cells’ capacity to decompose H2O2 determines lenalidomide sensitivity
S Sebastian, YX Zhu, E Braggio, CX Shi, SC Panchabhai, SA Van Wier, ...
Blood, The Journal of the American Society of Hematology 129 (8), 991-1007, 2017
502017
Inactivation of the putative suppressor gene DOK1 by promoter hypermethylation in primary human cancers
A Saulnier, T Vaissière, J Yue, M Siouda, M Malfroy, R Accardi, ...
International journal of cancer 130 (11), 2484-2494, 2012
402012
Evaluation of Revised International Staging System (R-ISS) for transplant-eligible multiple myeloma patients
V González-Calle, A Slack, N Keane, S Luft, KE Pearce, RP Ketterling, ...
Annals of hematology 97, 1453-1462, 2018
372018
PKM2 and other key regulators of Warburg effect positively correlate with CD147 (EMMPRIN) gene expression and predict survival in multiple myeloma
S Panchabhai, I Schlam, S Sebastian, R Fonseca
Leukemia 31 (4), 991-994, 2017
312017
PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation
PJ Teoh, C Bi, C Sintosebastian, LS Tay, R Fonseca, WJ Chng
Oncotarget 7 (38), 61806, 2016
302016
p53 as the main traffic controller of the cell signaling network
S Sebastian, A Azzariti, N Silvestris, L Porcelli, A Russo, A Paradiso
Front Biosci 15, 1172-1190, 2010
232010
Telomeres, telomerase and oral cancer
S Sebastian, L Grammatica, A Paradiso
International journal of oncology 27 (6), 1583-1596, 2005
182005
Wip1 contributes to cell homeostasis maintained by the steady-state level of Wtp53
HK Park, J Panneerselvam, FD Dudimah, G Dong, S Sebastian, J Zhang, ...
Cell cycle 10 (15), 2574-2582, 2011
172011
Validation of gefitinib effectiveness in a broad panel of head and neck squamous carcinoma cells
S Sebastian, A Azzariti, R Accardi, D Conti, B Pilato, R LaCalamita, ...
International journal of molecular medicine 21 (6), 809-817, 2008
112008
Prediction of immunomodulatory drugs (IMiDs) sensitivity in myeloma via determination of baseline anti-oxidative stress capacity
L Mountjoy, S Sebastian, T Jain, T Hilal, M Gonzalez-Velez, M Girardo, ...
Leukemia 34 (11), 3060-3063, 2020
92020
PARP Inhibition (OLAPARIB) Enhance Melphalan and Nutlin-3a Sensitivity in TP53 Positive Multiple Myeloma
S Sebastian, M Chesi, E Braggio, L Bergsagel, K Stewart, G Ahmann, ...
Blood 120 (21), 1846, 2012
32012
Unraveling Antioxidative Metabolic Pathways in Multiple Myeloma: Augmenting IMiD Sensitivity through Intracellular Cysteine Biosynthesis Inhibition
SS Chirackal, T Hitosugi, G Ahmann, E Braggio, M Chesi, PL Bergsagel, ...
Blood 142, 3291, 2023
2023
Myeloma Cells Addicted to Glutamine for Biomass Production Are Sensitive to Lenalidomide
S Chirackal, E Braggio, R Atiqur, GJ Ahmann, YX Zhu, AK Stewart, ...
Blood 134, 4410, 2019
2019
Results of a Flow Cytometry Assay Measuring Oxidative Stress Relief As a Predictor of Immunomodulatory Drugs (IMIDs) Sensitivity in Myeloma
L Mountjoy, S Chirackal, T Jain, M Girardo, J Larsen, R Fonseca
Blood 132, 4443, 2018
2018
Methods and materials for assessing hydrogen peroxide accumulation in cells
SS Chirackal, R Fonseca
US Patent App. 15/737,219, 2018
2018
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