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Sharon Spizzichino
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Design, Synthesis and Discovery of N,N’‐Carbazoyl‐aryl‐urea Inhibitors of Zika NS5 Methyltransferase and Virus Replication
S Spizzichino, G Mattedi, K Lauder, C Valle, W Aouadi, B Canard, ...
ChemMedChem 15 (4), 385-390, 2020
192020
Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex
S Spizzichino, D Boi, G Boumis, R Lucchi, FR Liberati, D Capelli, ...
The FEBS Journal 289 (6), 1625-1649, 2022
42022
The emerging role of amino acids of the brain microenvironment in the process of metastasis formation
F Cutruzzolà, A Bouzidi, FR Liberati, S Spizzichino, G Boumis, A Macone, ...
Cancers 13 (12), 2891, 2021
42021
A conserved scaffold with heterogeneous metal ion binding site: the multifaceted example of HD-GYP proteins
F Cutruzzolà, A Paiardini, CS Rossi, S Spizzichino, A Paone, G Giardina, ...
Coordination Chemistry Reviews 450, 214228, 2022
32022
Crystal structure of Aspergillus fumigatus AroH, an aromatic amino acid aminotransferase
S Spizzichino, G Pampalone, M Dindo, A Bruno, L Romani, F Cutruzzolà, ...
Proteins: Structure, Function, and Bioinformatics 90 (2), 435-442, 2022
12022
Combined Delivery of miR-15/16 through Humanized Ferritin Nanocages for the Treatment of Chronic Lymphocytic Leukemia
FR Liberati, S Di Russo, L Barolo, G Peruzzi, MV Farina, S Spizzichino, ...
Pharmaceutics 16 (3), 402, 2024
2024
THE RIBOREGULATION MECHANISM OF HUMAN SERINE HYDROXYMETHYLTRANSFERASE IS ROOTED IN AN ALLOSTERIC SWITCH
S Spizzichino, F Di Fonzo, C Marabelli, A Tramonti, A Chaves-Sanjuan, ...
bioRxiv, 2023.03. 17.532973, 2023
2023
Riboregulation of human serine hydroxymethyltransferase activity in cellular metabolism
FR Liberati, A Bouzidi, S Spizzichino, F Di Fonzo, G Boumis, S Rinaldo, ...
FEBS OPEN BIO 12, 288-289, 2022
2022
Serine hydroxymethyltransferase: more than a metabolic enzyme
F Di Fonzo, FR Liberati, A Bouzidi, S Spizzichino, G Boumis, G Giardina, ...
FEBS OPEN BIO 12, 290-290, 2022
2022
One protein many functions: the non-canonical interactions of SHMT1. The structural and functional characterization of SHMT1 interactions with RNA and in the de novo …
S Spizzichino
Università degli Studi di Roma" La Sapienza", 2022
2022
Riboregulation as a new player in the control of cellular metabolism: clues from the cryo-EM structure of serine hydroxymethyltransferase-RNA complex
G Giardina, S Spizzichino, M Chiara, F DI FONZO, A Tramonti, A Parroni, ...
Abstract Book, 2022
2022
Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex
S Spizzichino, D Boi, G Boumis, A Tramonti, A Paiardini, R Contestabile, ...
FEBS OPEN BIO 11, 196-196, 2021
2021
Riboregulation of human serine hydroxymethyltransferase activity in cellular metabolism
FR Liberati, A Bouzidi, S Spizzichino, F Di Fonzo, G Boumis, S Rinaldo, ...
FEBS OPEN BIO 11, 78-78, 2021
2021
Intrinsically disordered regions of alanine: glyoxylate aminotransferase shape its fitness and function
M Dindo, G Giardina, S Pascarelli, D Chiasserini, S Grottelli, G Uechi, ...
FEBS OPEN BIO 11, 177-177, 2021
2021
The Emerging Role of Amino Acids of the Brain Microenvironment in the Process of Metastasis Formation. Cancers 2021, 13, 2891
F Cutruzzolà, A Bouzidi, FR Liberati, S Spizzichino, G Boumis, A Macone, ...
s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021
2021
Structural clues of Serine hidroxymethyltransferase (SHMT) riboregulation
S Spizzichino, M Chiara, AC Sanjuan, S Paolo, LC Montemiglio, A Matteo, ...
2nd Italian Crystallographic Association Biological MacroMolecules Group Meeting, 2021
2021
Targeting de novo thymidylate synthesis nuclear complex
G Boumis, S Spizzichino, G Giardina, S Rinaldo, A Paone, A Paiardini, ...
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