The β-secretase BACE1 in Alzheimer’s disease Biological Psychiatry, 2020 | 466* | 2020 |
IRAK-1 contributes to lipopolysaccharide-induced reactive oxygen species generation in macrophages by inducing NOX-1 transcription and Rac1 activation and suppressing the … U Maitra, N Singh, L Gan, L Ringwood, L Li Journal of Biological Chemistry 284 (51), 35403-35411, 2009 | 121 | 2009 |
Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease R Gordon, N Singh, V Lawana, A Ghosh, DS Harischandra, H Jin, ... Neurobiology of disease 93, 96-114, 2016 | 100 | 2016 |
Kv1.3 modulates neuroinflammation and neurodegeneration in Parkinson’s disease JCI, 2020 | 97* | 2020 |
Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress signaling events Neeraj Singh, Vivek Lawana, Jie Luo, Phang Phong, Ahmed Abdallaa, Bharathi ... Neurobiology of Disease, 2018 | 97 | 2018 |
Treatment of neurodegenerative disorders with radical nanomedicine N Singh, CA Cohen, BA Rzigalinski Annals of the New York Academy of Sciences 1122 (1), 219-230, 2007 | 97 | 2007 |
Molecular mechanism underlying the suppression of lipid oxidation during endotoxemia U Maitra, S Chang, N Singh, L Li Molecular immunology 47 (2-3), 420-425, 2009 | 79 | 2009 |
Involvement of c-Abl kinase in microglial activation of NLRP3 inflammasome and impairment in autolysosomal system V Lawana, N Singh, S Sarkar, A Charli, H Jin, V Anantharam, ... Journal of Neuroimmune Pharmacology 12, 624-660, 2017 | 70 | 2017 |
Scavenger receptor class A member 3 (SCARA3) in disease progression and therapy resistance in multiple myeloma CO Brown, J Schibler, MP Fitzgerald, N Singh, K Salem, F Zhan, A Goel Leukemia research 37 (8), 963-969, 2013 | 70 | 2013 |
Interleukin-6 counteracts therapy-induced cellular oxidative stress in multiple myeloma by up-regulating manganese superoxide dismutase CO Brown, K Salem, BA Wagner, S Bera, N Singh, A Tiwari, A Choudhury, ... Biochemical journal 444 (3), 515-527, 2012 | 58 | 2012 |
BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1 N Singh, MR Benoit, J Zhou, B Das, J Davila-Velderrain, M Kellis, LH Tsai, ... Science Advances 8 (24), eabo1286, 2022 | 35 | 2022 |
The intracellular domain of CX3CL1 regulates adult neurogenesis and Alzheimer’s amyloid pathology Q Fan, M Gayen, N Singh, F Gao, W He, X Hu, LH Tsai, R Yan Journal of Experimental Medicine 216 (8), 1891-1903, 2019 | 35 | 2019 |
Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance RY Neeraj Singh, Brati Das, John Zhou, Xiangyou Hu Science Advances 8 (29), eabo3610, 2022 | 31 | 2022 |
BACE1 controls synaptic function through modulating release of synaptic vesicles XHRY Brati Das, Neeraj Singh, Annie Yao, John Zhou Molecular Psychiatry, 2021 | 29 | 2021 |
Reduced oxidative tissue damage during endotoxemia in IRAK-1 deficient mice N Singh, L Li Molecular immunology 50 (4), 244-252, 2012 | 29 | 2012 |
The Antioxidant Activity of Cerium Oxide Nanoparticles is Size Dependant and Blocks Aβ1‐42‐Induced Free Radical Production and Neurotoxicity N Singh, E Amateis, JE Mahaney, K Meehan, BA Rzigalinski The FASEB Journal 22, 624.2-624.2, 2008 | 19 | 2008 |
Molecular mechanism underlying LPS‐induced generation of reactive oxygen species in macrophages L Li, U Maitra, N Singh, L Gan The FASEB Journal 24, 422.3-422.3, 2010 | 13 | 2010 |
Cerium oxide nanoparticles for treatment and prevention of alzheimer's disease, parkinson's disease, and disorders associated with free radical production and/or mitochondrial … BA Rzigalinski, N Singh, CA Cohen US Patent 10,857,178, 2020 | 10 | 2020 |
Antioxidant properties of cerium oxide nanoparticles N Singh, C Liang, B Rzigalinski FREE RADICAL BIOLOGY AND MEDICINE 41, S152-S152, 2006 | 6 | 2006 |
BACE1 regulates expression of Clusterin in astrocytes for enhancing clearance of β-amyloid peptides XHRY John Zhou, Neeraj Singh, James Galske, Jacob Hudobenko Molecular Neurodegeneration 18 (31), 2023 | 5 | 2023 |