CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II–transcribed genes C Laitem, J Zaborowska, NF Isa, J Kufs, M Dienstbier, S Murphy Nature structural & molecular biology 22 (5), 396-403, 2015 | 126 | 2015 |
Facile assembly and fluorescence-based screening method for heterologous expression of biosynthetic pathways in fungi S Hoefgen, J Lin, J Fricke, MC Stroe, DJ Mattern, JE Kufs, P Hortschansky, ... Metabolic engineering 48, 44-51, 2018 | 70 | 2018 |
Engineering the amoeba Dictyostelium discoideum for biosynthesis of a cannabinoid precursor and other polyketides C Reimer, JE Kufs, J Rautschek, L Regestein, V Valiante, F Hillmann Nature biotechnology 40 (5), 751-758, 2022 | 22 | 2022 |
Rational design of flavonoid production routes using combinatorial and precursor-directed biosynthesis JE Kufs, S Hoefgen, J Rautschek, AU Bissell, C Graf, J Fiedler, D Braga, ... ACS Synthetic Biology 9 (7), 1823-1832, 2020 | 17 | 2020 |
Biosynthesis of the sphingolipid inhibitors sphingofungins in filamentous fungi requires aminomalonate as a metabolic precursor AU Bissell, J Rautschek, S Hoefgen, L Raguz, DJ Mattern, N Saeed, ... ACS Chemical Biology 17 (2), 386-394, 2022 | 8 | 2022 |
Scale-up of an amoeba-based process for the production of the cannabinoid precursor olivetolic acid JE Kufs, C Reimer, E Steyer, V Valiante, F Hillmann, L Regestein Microbial Cell Factories 21 (1), 217, 2022 | 4 | 2022 |
The potential of amoeba-based processes for natural product syntheses JE Kufs, C Reimer, P Stallforth, F Hillmann, L Regestein Current Opinion in Biotechnology 77, 102766, 2022 | 4 | 2022 |
Yellow polyketide pigment suppresses premature hatching in social amoeba M Günther, C Reimer, R Herbst, JE Kufs, J Rautschek, N Ueberschaar, ... Proceedings of the National Academy of Sciences 119 (43), e2116122119, 2022 | 3 | 2022 |
The isoprenyl chain length of coenzyme Q mediates the nutritional resistance of fungi to amoeba predation N Saeed, V Valiante, JE Kufs, F Hillmann Mbio 15 (6), e00342-24, 2024 | | 2024 |
Method for producing olivetolic acid in an amoebozoa host species F Hillmann, C Reimer, JE Kufs, V Valiante US Patent App. 18/013,082, 2023 | | 2023 |
Developing Molecular Tools for the de Novo Assembling of Biosynthetic Routes J Kufs Friedrich-Schiller-Universität Jena, 2020 | | 2020 |