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Norman E. Sharpless
Norman E. Sharpless
Former Director, The National Cancer Institute
Verified email at med.unc.edu
Title
Cited by
Cited by
Year
Circular RNAs are abundant, conserved, and associated with ALU repeats
WR Jeck, JA Sorrentino, K Wang, MK Slevin, CE Burd, J Liu, WF Marzluff, ...
Rna 19 (2), 141-157, 2013
43862013
Genomic classification of cutaneous melanoma
R Akbani, KC Akdemir, B áArman Aksoy, M Albert, A Ally, SB Amin, ...
Cell 161 (7), 1681-1696, 2015
28912015
Detecting and characterizing circular RNAs
WR Jeck, NE Sharpless
Nature biotechnology 32 (5), 453-461, 2014
26002014
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
J Chang, Y Wang, L Shao, RM Laberge, M Demaria, J Campisi, ...
Nature medicine 22 (1), 78-83, 2016
18242016
Ink4a/Arf expression is a biomarker of aging
J Krishnamurthy, C Torrice, MR Ramsey, GI Kovalev, K Al-Regaiey, L Su, ...
The Journal of clinical investigation 114 (9), 1299-1307, 2004
17932004
Senescence in health and disease
S He, NE Sharpless
Cell 169 (6), 1000-1011, 2017
16602017
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a
V Janzen, R Forkert, HE Fleming, Y Saito, MT Waring, DM Dombkowski, ...
Nature 443 (7110), 421-426, 2006
13052006
Cellular senescence promotes adverse effects of chemotherapy and cancer relapse. Cancer Discov.
M Demaria, MN O’leary, J Chang, L Shao, S Liu, F Alimirah, K Koenig, ...
CD-16-0241.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 2017
1272*2017
The regulation of INK4/ARF in cancer and aging
WY Kim, NE Sharpless
Cell 127 (2), 265-275, 2006
12552006
LKB1 modulates lung cancer differentiation and metastasis
H Ji, MR Ramsey, DN Hayes, C Fan, K McNamara, P Kozlowski, C Torrice, ...
Nature 448 (7155), 807-810, 2007
12082007
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing
AV Molofsky, SG Slutsky, NM Joseph, S He, R Pardal, J Krishnamurthy, ...
Nature 443 (7110), 448-452, 2006
11642006
Forging a signature of in vivo senescence
NE Sharpless, CJ Sherr
Nature Reviews Cancer 15 (7), 397-408, 2015
11422015
p16INK4a induces an age-dependent decline in islet regenerative potential
J Krishnamurthy, MR Ramsey, KL Ligon, C Torrice, A Koh, S Bonner-Weir, ...
Nature 443 (7110), 453-457, 2006
11302006
How stem cells age and why this makes us grow old
NE Sharpless, RA DePinho
Nature reviews Molecular cell biology 8 (9), 703-713, 2007
11092007
Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk
CE Burd, WR Jeck, Y Liu, HK Sanoff, Z Wang, NE Sharpless
PLoS genetics 6 (12), e1001233, 2010
10262010
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis
NE Sharpless, N Bardeesy, KH Lee, D Carrasco, DH Castrillon, ...
Nature 413 (6851), 86-91, 2001
10132001
Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer
JS Duncan, MC Whittle, K Nakamura, AN Abell, AA Midland, ...
Cell 149 (2), 307-321, 2012
8732012
Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
RM Bachoo, EA Maher, KL Ligon, NE Sharpless, SS Chan, MJ You, ...
Cancer cell 1 (3), 269-277, 2002
8522002
The mighty mouse: genetically engineered mouse models in cancer drug development
NE Sharpless, RA DePinho
Nature reviews Drug discovery 5 (9), 741-754, 2006
7892006
The INK4A/ARF locus and its two gene products
NE Sharpless, RA DePinho
Current opinion in genetics & development 9 (1), 22-30, 1999
7091999
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Articles 1–20