| Discovery, characterization, and effects on renal fluid and electrolyte excretion of the Kir4. 1 potassium channel pore blocker, VU0134992 SV Kharade, H Kurata, AM Bender, AL Blobaum, EE Figueroa, A Duran, ... Molecular pharmacology 94 (2), 926-937, 2018 | 50 | 2018 |
| ML418: The first selective, sub-micromolar pore blocker of Kir7. 1 potassium channels DR Swale, H Kurata, SV Kharade, J Sheehan, R Raphemot, KR Voigtritter, ... ACS chemical neuroscience 7 (7), 1013-1023, 2016 | 26 | 2016 |
| LRRC8A homohexameric channels poorly recapitulate VRAC regulation and pharmacology T Yamada, EE Figueroa, JS Denton, K Strange American Journal of Physiology-Cell Physiology 320 (3), C293-C303, 2021 | 20 | 2021 |
| The LRRC8 volume‐regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel A Afzal, EE Figueroa, SV Kharade, K Bittman, BK Matlock, DK Flaherty, ... Physiological reports 7 (23), e14303, 2019 | 20 | 2019 |
| Pore polarity and charge determine differential block of Kir1. 1 and Kir7. 1 potassium channels by small-molecule inhibitor VU590 SV Kharade, JH Sheehan, EE Figueroa, J Meiler, JS Denton Molecular pharmacology 92 (3), 338-346, 2017 | 18 | 2017 |
| CysLT1 receptor antagonists pranlukast and zafirlukast inhibit LRRC8-mediated volume regulated anion channels independently of the receptor EE Figueroa, M Kramer, K Strange, JS Denton American Journal of Physiology-Cell Physiology 317 (4), C857-C866, 2019 | 15 | 2019 |
| A SWELL time to develop the molecular pharmacology of the volume-regulated anion channel (VRAC) EE Figueroa, JS Denton Channels 16 (1), 27-36, 2022 | 10 | 2022 |
| Identification of a drug binding pocket in TMEM16F calcium-activated ion channel and lipid scramblase S Feng, C Puchades, J Ko, H Wu, Y Chen, EE Figueroa, S Gu, TW Han, ... Nature Communications 14 (1), 4874, 2023 | 9 | 2023 |
| Identification of a conserved drug binding pocket in TMEM16 proteins Y Cheng, S Feng, C Puchades, J Ko, E Figueroa, Y Chen, H Wu, S Gu, ... Research Square, 2022 | 9 | 2022 |
| Zinc pyrithione activates the volume-regulated anion channel through an antioxidant-sensitive mechanism EE Figueroa, JS Denton American Journal of Physiology-Cell Physiology 320 (6), C1088-C1098, 2021 | 8 | 2021 |
| Developing the Molecular Pharmacology of LRRC8-containing Volume-Regulated Anion Channels EE Figueroa Vanderbilt University, 2020 | 2 | 2020 |
| Identification of a conserved drug binding pocket in TMEM16 proteins (preprint) Y Cheng, S Feng, C Puchades, J Ko, E Figueroa, Y Chen, H Wu, S Gu, ... | | 2022 |
| Development of Small-Molecule Inhibitors of Proton-Activated Chloride Channels EE Figueroa, JS Denton Biophysical Journal 118 (3), 590a, 2020 | | 2020 |
| CysLT1 Receptor Antagonists Pranlukast and Zafirlukast Inhibit LRRC8-Mediated Volume Regulated Anion Channels Independently of the Receptor EE Figueroa, JS Denton Biophysical Journal 118 (3), 587a-588a, 2020 | | 2020 |
| Discovery of Pranlukast in a High‐Throughput Screen for Novel Inhibitors of LRRC8 Volume Regulated Anion Channels EE Figueroa, M Kramer, JS Denton The FASEB Journal 33 (S1), 824.3-824.3, 2019 | | 2019 |
| Discovery, characterization, and preclinical development of a Kir4.1 (KCNJ10) inhibitor for the treatment of hypertension SV Kharade, H Kurata, E Figueroa, AL Blobaum, M Kramer, C Lindsley, ... The FASEB Journal 32, 829.8-829.8, 2018 | | 2018 |
| Development of novel inhibitors of swelling‐activated LRRC8 anion channels E Figueroa, M Fulton, S Kharade, M Kramer, D Weaver, C Lindsley, ... The FASEB Journal 32, 567.3-567.3, 2018 | | 2018 |
| ML418: The first selective, sub-micromolar pore blocker of Kir7. 1 potassium channels H Kurata, D Swale, S Kharade, J Sheehan, R Raphemot, K Voigtritter, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
| VU590 inhibits Kir1. 1 and Kir7. 1 potassium channels through distinct molecular mechanisms SV Kharade, EE Figueroa, JS Denton The FASEB Journal 31, 991.15-991.15, 2017 | | 2017 |
| Visiting Scholars and BlastOff! Flow from BECUR (29.3) W Cai, C Cheah, A Phan, N Seto, S Taniguchi, E Figueroa, J Hazzard The FASEB Journal 28, 29.3, 2014 | | 2014 |
