Altered RNA splicing by mutant p53 activates oncogenic RAS signaling in pancreatic cancer LF Escobar-Hoyos, A Penson, R Kannan, H Cho, CH Pan, RK Singh, ... Cancer cell 38 (2), 198-211. e8, 2020 | 131 | 2020 |
Keratin 17 identifies the most lethal molecular subtype of pancreatic cancer L Roa-Peña, CV Leiton, S Babu, CH Pan, EA Vanner, A Akalin, ... Scientific reports 9 (1), 11239, 2019 | 61 | 2019 |
Vorinostat enhances the cisplatin-mediated anticancer effects in small cell lung cancer cells CH Pan, YF Chang, MS Lee, BC Wen, JC Ko, SK Liang, MC Liang BMC cancer 16, 1-11, 2016 | 46 | 2016 |
The PHLPP2 phosphatase is a druggable driver of prostate cancer progression DG Nowak, KC Katsenelson, KE Watrud, M Chen, G Mathew, ... Journal of Cell Biology 218 (6), 1943-1957, 2019 | 36 | 2019 |
Dissecting the oncogenic roles of keratin 17 in the hallmarks of cancer G Baraks, R Tseng, CH Pan, S Kasliwal, CV Leiton, KR Shroyer, ... Cancer research 82 (7), 1159-1166, 2022 | 22 | 2022 |
An unbiased high‐throughput drug screen reveals a potential therapeutic vulnerability in the most lethal molecular subtype of pancreatic cancer CH Pan, Y Otsuka, BP Sridharan, M Woo, CV Leiton, S Babu, ... Molecular Oncology 14 (8), 1800-1816, 2020 | 11 | 2020 |
Neutralizing activity to SARS‐CoV‐2 of convalescent and control plasma used in a randomized controlled trial AT Freedenberg, CH Pan, WE Diehl, JL Romeiser, GR Hwang, CV Leiton, ... Transfusion 61 (5), 1363-1369, 2021 | 10 | 2021 |
Alveolar Differentiation Drives Resistance to KRAS Inhibition in Lung Adenocarcinoma Z Li, X Zhuang, CH Pan, Y Yan, R Thummalapalli, J Hallin, S Torborg, ... Cancer Discovery 14 (2), 308-325, 2024 | 4 | 2024 |
Dihydroceramide desaturase 1 (DES1) promotes anchorage-independent survival downstream of HER2-driven glucose uptake and metabolism RW Linzer, DL Guida, J Aminov, JM Snider, G Khalife, AB Buyukbayraktar, ... FASEB journal: official publication of the Federation of American Societies …, 2022 | 4 | 2022 |
Targeting keratin 17-mediated reprogramming of de novo pyrimidine biosynthesis to overcome chemoresistance in pancreatic cancer CH Pan, NV Chaika, R Tseng, MA Siraj, B Chen, KL Donnelly, M Horowitz, ... bioRxiv, 2022.08. 24.504873, 2022 | 2 | 2022 |
Targeting Keratin 17 in Pancreatic Cancer: A Novel Rewired Pathway of Nucleotide Metabolism that Drives Chemoresistance CH Pan, R Tseng, K Donnelly, CV Leiton, SJ Hogg, N Marchenko, ... The FASEB Journal 36, 2022 | 2 | 2022 |
Disassembly of embryonic keratin filaments promotes pancreatic cancer metastases RR Kawalerski, MT Gonçalves, CH Pan, R Tseng, L Roa-Peña, CV Leiton, ... bioRxiv, 2022.08. 27.504988, 2022 | 1 | 2022 |
Abstract PO-050: Solubilization of keratin 17 promotes the metastatic dissemination of the most lethal form of pancreatic cancer RR Kawalerski, MT Gonçalves, L Roa-Peña, CV Leiton, CH Pan, ... Cancer Research 80 (22_Supplement), PO-050-PO-050, 2020 | 1 | 2020 |
Functional and molecular interrogation of a high-plasticity cell state in lung cancer JE Chan, CH Pan, C Sussman, H Styers, E Brown, G Hartmann, ... Cancer Research 84 (6_Supplement), 6626-6626, 2024 | | 2024 |
Abstract B085: K17-induced pyrimidine biosynthesis drives chemoresistance in PDAC Y Lyu, K Shroyer, CH Pan, R Tseng, MA Siraj, GH Rajacharya, B Chen, ... Cancer Research 84 (2_Supplement), B085-B085, 2024 | | 2024 |
Abstract C050: The unique metabolic signatures of keratin-17 expressing pancreatic ductal adenocarcinomas MM Salem, M Horowitz, L Oblein, CH Pan, N Marchenko, ... Cancer Research 84 (2_Supplement), C050-C050, 2024 | | 2024 |
Targeting keratin 17-mediated metabolic reprogramming of de novo pyrimidine biosynthesis as a novel strategy to overcome chemoresistance in pancreatic cancer CH Pan, R Tseng, M Horowitz, MA Sira, B Chen, KL Donnelly, CV Leiton, ... CANCER RESEARCH 82 (22), 60-60, 2022 | | 2022 |
Abstract B006: Targeting keratin 17-mediated metabolic reprogramming of de novo pyrimidine biosynthesis as a novel strategy to overcome chemoresistance in pancreatic cancer CH Pan, R Tseng, M Horowitz, MA Sira, B Chen, KL Donnelly, CV Leiton, ... Cancer Research 82 (22_Supplement), B006-B006, 2022 | | 2022 |
Disassembly of embryonic keratin filaments promotes pancreatic cancer metastases RR Kawalerski, MT Gonçalves, CH Pan, R Tseng, L Roa-Peña, CV Leiton, ... bioRxiv, 2022.08. 27.504988, 2022 | | 2022 |
Abstract PO-048: A novel chromatin remodeling domain of keratin 17 regulates transcription and promotes tumor aggression in pancreatic cancer CH Pan, R Tseng, SJ Hogg, G Baraks, CV Leiton, L Roa-Peña, ... Cancer Research 81 (22_Supplement), PO-048-PO-048, 2021 | | 2021 |