| A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo L Bai, H Zhou, R Xu, Y Zhao, K Chinnaswamy, D McEachern, J Chen, ... Cancer cell 36 (5), 498-511. e17, 2019 | 431 | 2019 |
| Structure-based discovery of SD-36 as a potent, selective, and efficacious PROTAC degrader of STAT3 protein H Zhou, L Bai, R Xu, Y Zhao, J Chen, D McEachern, K Chinnaswamy, ... Journal of medicinal chemistry 62 (24), 11280-11300, 2019 | 154 | 2019 |
| BM-1197: a novel and specific Bcl-2/Bcl-xL inhibitor inducing complete and long-lasting tumor regression in vivo L Bai, J Chen, D McEachern, L Liu, H Zhou, A Aguilar, S Wang PloS one 9 (6), e99404, 2014 | 109 | 2014 |
| Structure-based design of high-affinity macrocyclic peptidomimetics to block the menin-mixed lineage leukemia 1 (MLL1) protein–protein interaction H Zhou, L Liu, J Huang, D Bernard, H Karatas, A Navarro, M Lei, S Wang Journal of Medicinal Chemistry 56 (3), 1113-1123, 2013 | 101 | 2013 |
| Design of Bcl-2 and Bcl-xL inhibitors with subnanomolar binding affinities based upon a new scaffold H Zhou, J Chen, JL Meagher, CY Yang, A Aguilar, L Liu, L Bai, X Cong, ... Journal of medicinal chemistry 55 (10), 4664-4682, 2012 | 95 | 2012 |
| Short and efficient total synthesis of luotonin A and 22-hydroxyacuminatine using a common cascade strategy HB Zhou, GS Liu, ZJ Yao The Journal of Organic Chemistry 72 (16), 6270-6272, 2007 | 94 | 2007 |
| Highly efficient and mild cascade reactions triggered by bis (triphenyl) oxodiphosphonium trifluoromethanesulfonate and a concise total synthesis of camptothecin HB Zhou, GS Liu, ZJ Yao Organic Letters 9 (10), 2003-2006, 2007 | 87 | 2007 |
| A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation H Zhou, J Lu, L Liu, D Bernard, CY Yang, E Fernandez-Salas, ... Nature communications 8 (1), 1150, 2017 | 83 | 2017 |
| Structure-based design of potent Bcl-2/Bcl-xL inhibitors with strong in vivo antitumor activity H Zhou, A Aguilar, J Chen, L Bai, L Liu, JL Meagher, CY Yang, ... Journal of medicinal chemistry 55 (13), 6149-6161, 2012 | 76 | 2012 |
| Structure-based discovery of BM-957 as a potent small-molecule inhibitor of Bcl-2 and Bcl-xL capable of achieving complete tumor regression J Chen, H Zhou, A Aguilar, L Liu, L Bai, D McEachern, CY Yang, ... Journal of medicinal chemistry 55 (19), 8502-8514, 2012 | 71 | 2012 |
| A potent and highly efficacious Bcl-2/Bcl-xL inhibitor A Aguilar, H Zhou, J Chen, L Liu, L Bai, D McEachern, CY Yang, ... Journal of medicinal chemistry 56 (7), 3048-3067, 2013 | 62 | 2013 |
| Cullin 4B protein ubiquitin ligase targets peroxiredoxin III for degradation X Li, D Lu, F He, H Zhou, Q Liu, Y Wang, C Shao, Y Gong Journal of Biological Chemistry 286 (37), 32344-32354, 2011 | 60 | 2011 |
| High-affinity peptidomimetic inhibitors of the DCN1-UBC12 protein–protein interaction H Zhou, W Zhou, B Zhou, L Liu, TR Chern, K Chinnaswamy, J Lu, ... Journal of Medicinal Chemistry 61 (5), 1934-1950, 2018 | 54 | 2018 |
| MicroRNA-26a-5p and microRNA-23b-3p up-regulate peroxiredoxin III in acute myeloid leukemia W Jiang, J Min, X Sui, Y Qian, Y Liu, Z Liu, H Zhou, X Li, Y Gong Leukemia & lymphoma 56 (2), 460-471, 2015 | 46 | 2015 |
| Bcl-2/Bcl-xL inhibitors and therapeutic methods using the same S Wang, H Zhou, J Chen, A Aguilar, JL Meagher, D Sun, CY Yang, L Liu, ... US Patent 8,691,184, 2014 | 44 | 2014 |
| Resveratrol sequentially induces replication and oxidative stresses to drive p53-CXCR2 mediated cellular senescence in cancer cells B Li, D Hou, H Guo, H Zhou, S Zhang, X Xu, Q Liu, X Zhang, Y Zou, ... Scientific reports 7 (1), 208, 2017 | 43 | 2017 |
| Metal-free synthesis of alkynyl imines using an oxophosphonium-mediated approach at ambient temperatures QL Dong, GS Liu, HB Zhou, L Chen, ZJ Yao Tetrahedron Letters 49 (10), 1636-1640, 2008 | 43 | 2008 |
| SD-91 as a potent and selective STAT3 degrader capable of achieving complete and long-lasting tumor regression H Zhou, L Bai, R Xu, D McEachern, K Chinnaswamy, R Li, B Wen, ... ACS Medicinal Chemistry Letters 12 (6), 996-1004, 2021 | 27 | 2021 |
| Modification of poorly bioactive sinomenine into more potent immunosuppressive agents by embedding of drug-like fragments YT Lou, HB Zhou, J Zou, LC Yan, EG Bi, B Sun, ZJ Yao Tetrahedron Letters 51 (3), 485-488, 2010 | 26 | 2010 |
| An inexpensive fluorescent labeling protocol for bioactive natural products utilizing Cu (I)-catalyzed Huisgen reaction YH Zhang, ZX Gao, CL Zhong, HB Zhou, L Chen, WM Wu, XJ Peng, ... Tetrahedron 63 (29), 6813-6821, 2007 | 26 | 2007 |
