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Fredrik Thege
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Detection of circulating pancreas epithelial cells in patients with pancreatic cystic lesions
AD Rhim, FI Thege, SM Santana, TB Lannin, TN Saha, S Tsai, LR Maggs, ...
Gastroenterology 146 (3), 647-651, 2014
2382014
Microfluidic immunocapture of circulating pancreatic cells using parallel EpCAM and MUC1 capture: characterization, optimization and downstream analysis
FI Thege, TB Lannin, TN Saha, S Tsai, ML Kochman, MA Hollingsworth, ...
Lab on a Chip 14 (10), 1775-1784, 2014
1392014
Comparison and optimization of machine learning methods for automated classification of circulating tumor cells
TB Lannin, FI Thege, BJ Kirby
Cytometry Part A 89 (10), 922-931, 2016
422016
APOBEC3A drives deaminase domain-independent chromosomal instability to promote pancreatic cancer metastasis
SM Wörmann, A Zhang, FI Thege, RW Cowan, DN Rupani, R Wang, ...
Nature Cancer 2 (12), 1338-1356, 2021
362021
Automated electrorotation shows electrokinetic separation of pancreatic cancer cells is robust to acquired chemotherapy resistance, serum starvation, and EMT
T Lannin, WW Su, C Gruber, I Cardle, C Huang, F Thege, B Kirby
Biomicrofluidics 10 (6), 2016
342016
anti-EGFR capture mitigates EMT-and chemoresistance-associated heterogeneity in a resistance-profiling CTC platform
FI Thege, CN Gruber, II Cardle, SH Cong, TB Lannin, BJ Kirby
Analytical biochemistry 577, 26-33, 2019
142019
Spatial Transcriptomics of Intraductal papillary mucinous neoplasms of the Pancreas identifies Nkx6-2 as a driver of gastric differentiation and indolent biological potential
M Sans, Y Makino, J Min, KI Rajapakshe, M Yip-Schneider, CM Schmidt, ...
Cancer discovery 13 (8), 1844-1861, 2023
102023
A Programmable In Vivo CRISPR Activation Model Elucidates the Oncogenic and Immunosuppressive Functions of MYC in Lung Adenocarcinoma
FI Thege, DN Rupani, BB Barathi, SL Manning, A Maitra, AD Rhim, ...
Cancer research 82 (15), 2761-2776, 2022
92022
Single-step microfluidic generation of cell-sized giant unilamellar vesicles: Characterization and dielectrophoretic patterning and sorting
F Thege
22011
Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling
DN Rupani, FI Thege, V Chandra, H Rajaei, RW Cowan, SM Wörmann, ...
Development 150 (2), dev201097, 2023
12023
Integrated spatial transcriptomics and lipidomics analyses of intraductal papillary mucinous neoplasm identifies enrichment of long chain sulfatide as an early metabolic alteration
Y Chen, M Sans, F Thege, R Dou, J Min, M Yip-Schneider, J Zhang, R Wu, ...
Cancer Research 84 (6_Supplement), 446-446, 2024
2024
Abstract C057: Delineating tissue-specific oncogene selection with autochthonous CRISPR activation screening
FI Thege, SM Woermann, A Maitra
Cancer Research 84 (2_Supplement), C057-C057, 2024
2024
Abstract B058: Mutant GNAS drives glycolytic dependency in intraductal papillary mucinous neoplasms of the pancreas
Y Makino, K Rajapakshe, N Yee, M Siemann, J Min, BC Selvanesan, ...
Cancer Research 84 (2_Supplement), B058-B058, 2024
2024
Metabolic Reprogramming by Mutant GNAS Creates an Actionable Dependency in Intraductal Papillary Mucinous Neoplasms of the Pancreas
Y Makino, KI Rajapakshe, BC Selvanesan, T Okumura, K Date, P Dutta, ...
bioRxiv, 2024.03. 13.584524, 2024
2024
Role of Apobec3a in pancreatitis and inflammation triggered carcinogenesis
SM Woermann, F Thege, L Valenciana, R Cowan, A Maitra
Cancer Research 83 (7_Supplement), 636-636, 2023
2023
In vivo CRISPR activation screening identifies tissue-specific oncogene selection
FI Thege, SM Woermann, A Maitra
Cancer Research 83 (7_Supplement), 3-3, 2023
2023
Integrated spatial transcriptomics and lipidomics of precursor lesions of pancreatic cancer identifies enrichment of long chain sulfatide biosynthesis as an early metabolic …
M Sans, Y Chen, FI Thege, R Dou, J Min, M Yip-Schneider, J Zhang, ...
bioRxiv, 2023.08. 14.553002, 2023
2023
APOBEC3A a causative agent in cancer-related chromosomal instability and STING driven metastasis
SM Woermann, A Zhang, FI Thege, C Gates, RS Harris, SR Ross, F Notta, ...
Cancer Research 82 (12_Supplement), 1506-1506, 2022
2022
Development of a platform for programmable in vivo oncogene activation and screening using CRISPRa technology
FI Thege, DN Rupani, BB Barathi, A Maitra, AD Rhim, SM Wörmann
Cancer Research 82 (12_Supplement), 918-918, 2022
2022
Acquired chemoresistance drives spatial heterogeneity, chemoprotection and collective migration in pancreatic tumor spheroids
FI Thege, II Cardle, CN Gruber, MJ Siemann, S Cong, K Wittmann, J Love, ...
Plos one 17 (5), e0267882, 2022
2022
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