| Familial Alzheimer’s disease mutations in amyloid protein precursor alter proteolysis by γ-secretase to increase amyloid β-peptides of≥ 45 residues S Devkota, TD Williams, MS Wolfe Journal of Biological Chemistry 296, 2021 | 50 | 2021 |
| Mechanisms of γ-secretase activation and substrate processing A Bhattarai, S Devkota, S Bhattarai, MS Wolfe, Y Miao ACS central science 6 (6), 969-983, 2020 | 43 | 2020 |
| Mechanism of tripeptide trimming of amyloid β-peptide 49 by γ-secretase A Bhattarai, S Devkota, HN Do, J Wang, S Bhattarai, MS Wolfe, Y Miao Journal of the American Chemical Society 144 (14), 6215-6226, 2022 | 30 | 2022 |
| Scaffold protein SLP-76 primes PLCγ1 for activation by ITK-mediated phosphorylation S Devkota, RE Joseph, L Min, DB Fulton, AH Andreotti Journal of molecular biology 427 (17), 2734-2747, 2015 | 24 | 2015 |
| An autoinhibitory role for the pleckstrin homology domain of interleukin-2-inducible tyrosine kinase and its interplay with canonical phospholipid recognition S Devkota, RE Joseph, SE Boyken, DB Fulton, AH Andreotti Biochemistry 56 (23), 2938-2949, 2017 | 19 | 2017 |
| Design of substrate transmembrane mimetics as structural probes for γ-secretase S Bhattarai, S Devkota, KM Meneely, M Xing, JT Douglas, MS Wolfe Journal of the American Chemical Society 142 (7), 3351-3355, 2020 | 12 | 2020 |
| Effects of presenilin-1 familial Alzheimer’s disease mutations on γ-secretase activation for cleavage of amyloid precursor protein HN Do, S Devkota, A Bhattarai, MS Wolfe, Y Miao Communications Biology 6 (1), 174, 2023 | 10 | 2023 |
| Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes S Devkota, R Zhou, V Nagarajan, M Maesako, H Do, A Noorani, ... Cell reports 43 (2), 2024 | 8 | 2024 |
| Design of Transmembrane Mimetic Structural Probes to Trap Different Stages of γ-Secretase–Substrate Interaction S Bhattarai, S Devkota, MS Wolfe Journal of medicinal chemistry 64 (20), 15367-15378, 2021 | 6 | 2021 |
| Designed helical peptides as functional probes for γ-secretase AT Philip, S Devkota, S Malvankar, S Bhattarai, KM Meneely, TD Williams, ... Biochemistry 58 (44), 4398-4407, 2019 | 6 | 2019 |
| Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes S Devkota, R Zhou, V Nagarajan, M Maesako, H Do, A Noorani, ... bioRxiv, 2023.09. 08.556905, 2023 | 2 | 2023 |
| An autoinhibitory role for the Pleckstrin Homology domain of ITK and its interplay with canonical phospholipid recognition S Devkota, RE Joseph, SE Boyken, DB Fulton, AH Andreotti Biochemistry 56 (23), 2938, 2017 | 1 | 2017 |
| Alzheimer-mutant γ-secretase complexes stall amyloid β-peptide production P Arafi, S Devkota, M Maesako, MS Wolfe bioRxiv, 2024.08. 30.610520, 2024 | | 2024 |
| Effects of familial Alzheimer's disease mutations on gamma-secretase activation for cleavage of amyloid precursor protein HN Do, S Devkota, A Bhattarai, MS Wolfe, Y Miao Biophysical Journal 122 (3), 507a, 2023 | | 2023 |
| Mechanism of tripeptide trimming by γ-secretase A Bhattarai, S Devkota, HN Do, J Wang, S Bhattarai, MS Wolfe, Y Miao Biophysical Journal 121 (3), 87a, 2022 | | 2022 |
| Accelerated Molecular Simulations of Substrate Recognition by G-Secretase A Bhattarai, S Devkota, Y Miao, MS Wolfe, S Bhattarai Biophysical Journal 118 (3), 244a-245a, 2020 | | 2020 |
| Elucidation of regulatory mechanisms of the ITK and its substrate PLCγ1 S Devkota | | 2017 |
