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Michael Schwake
Michael Schwake
Northwestern University
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Year
LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of β-glucocerebrosidase
D Reczek, M Schwake, J Schröder, H Hughes, J Blanz, X Jin, W Brondyk, ...
Cell 131 (4), 770-783, 2007
6522007
ClC-5 Cl--channel disruption impairs endocytosis in a mouse model for Dent's disease
N Piwon, W Günther, M Schwake, MR Bösl, TJ Jentsch
Nature 408 (6810), 369-373, 2000
6152000
Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes
JR Lemke, D Lal, EM Reinthaler, I Steiner, M Nothnagel, M Alber, ...
Nature genetics 45 (9), 1067-1072, 2013
5082013
Phenotypic and biochemical analyses of BACE1-and BACE2-deficient mice
D Dominguez, J Tournoy, D Hartmann, T Huth, K Cryns, S Deforce, ...
Journal of Biological Chemistry 280 (35), 30797-30806, 2005
4632005
Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36
D Neculai, M Schwake, M Ravichandran, F Zunke, RF Collins, J Peters, ...
Nature 504 (7478), 172-176, 2013
3192013
Molecular determinants of KCNQ (Kv7) K+ channel sensitivity to the anticonvulsant retigabine
A Schenzer, T Friedrich, M Pusch, P Saftig, TJ Jentsch, J Grötzinger, ...
Journal of Neuroscience 25 (20), 5051-5060, 2005
3122005
Lysosomal membrane proteins and their central role in physiology
M Schwake, B Schröder, P Saftig
Traffic 14 (7), 739-748, 2013
2752013
GRIN2B mutations in west syndrome and intellectual disability with focal epilepsy
JR Lemke, R Hendrickx, K Geider, B Laube, M Schwake, RJ Harvey, ...
Annals of neurology 75 (1), 147-154, 2014
2582014
Surface expression and single channel properties of KCNQ2/KCNQ3, M-type K+ channels involved in epilepsy
M Schwake, M Pusch, T Kharkovets, TJ Jentsch
Journal of Biological Chemistry 275 (18), 13343-13348, 2000
2232000
Molecular expression and pharmacological identification of a role for Kv7 channels in murine vascular reactivity
SYM Yeung, V Pucovský, JD Moffatt, L Saldanha, M Schwake, S Ohya, ...
British journal of pharmacology 151 (6), 758-770, 2007
2152007
A carboxy‐terminal domain determines the subunit specificity of KCNQ K+ channel assembly
M Schwake, TJ Jentsch, T Friedrich
EMBO reports 4 (1), 76-81, 2003
1702003
An internalization signal in ClC-5, an endosomal Cl− channel mutated in Dent's disease
M Schwake, T Friedrich, TJ Jentsch
Journal of Biological Chemistry 276 (15), 12049-12054, 2001
1582001
LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson’s disease patients
D Ysselstein, M Nguyen, TJ Young, A Severino, M Schwake, K Merchant, ...
Nature communications 10 (1), 5570, 2019
1512019
Cathepsin F mutations cause Type B Kufs disease, an adult-onset neuronal ceroid lipofuscinosis
KR Smith, HHM Dahl, L Canafoglia, E Andermann, J Damiano, M Morbin, ...
Human molecular genetics 22 (7), 1417-1423, 2013
1472013
Refinement of the binding site and mode of action of the anticonvulsant Retigabine on KCNQ K+ channels
W Lange, J Geißendörfer, A Schenzer, J Grötzinger, G Seebohm, ...
Molecular pharmacology 75 (2), 272-280, 2009
1442009
Disease-causing mutations within the lysosomal integral membrane protein type 2 (LIMP-2) reveal the nature of binding to its ligand β-glucocerebrosidase
J Blanz, J Groth, C Zachos, C Wehling, P Saftig, M Schwake
Human molecular genetics 19 (4), 563-572, 2010
1382010
LIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearance
M Rothaug, F Zunke, JR Mazzulli, M Schweizer, H Altmeppen, ...
Proceedings of the National Academy of Sciences 111 (43), 15573-15578, 2014
1372014
Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export
S Heybrock, K Kanerva, Y Meng, C Ing, A Liang, ZJ Xiong, X Weng, ...
Nature communications 10 (1), 3521, 2019
1352019
Tetraspanin15 regulates cellular trafficking and activity of the ectodomain sheddase ADAM10
J Prox, M Willenbrock, S Weber, T Lehmann, D Schmidt-Arras, ...
Cellular and Molecular Life Sciences 69, 2919-2932, 2012
1352012
Structural determinants of M-type KCNQ (Kv7) K+ channel assembly
M Schwake, D Athanasiadu, C Beimgraben, J Blanz, C Beck, TJ Jentsch, ...
Journal of Neuroscience 26 (14), 3757-3766, 2006
1242006
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