| Insulin-like growth factor I receptor pathway inhibition by ADW742, alone or in combination with imatinib, doxorubicin, or vincristine, is a novel therapeutic approach in Ewing … AS Martins, C Mackintosh, DH Martín, M Campos, T Hernández, ... Clinical Cancer Research 12 (11), 3532-3540, 2006 | 144 | 2006 |
| Advances in Ewing's sarcoma research: where are we now and what lies ahead? JL Ordóñez, D Osuna, D Herrero, E de Alava, J Madoz-Gúrpide Cancer research 69 (18), 7140-7150, 2009 | 142 | 2009 |
| Stable interference of EWS–FLI1 in an Ewing sarcoma cell line impairs IGF-1/IGF-1R signalling and reveals TOPK as a new target D Herrero-Martin, D Osuna, JL Ordonez, V Sevillano, AS Martins, ... British journal of cancer 101 (1), 80-90, 2009 | 139 | 2009 |
| 1q gain and CDT2 overexpression underlie an aggressive and highly proliferative form of Ewing sarcoma C Mackintosh, JL Ordonez, DJ Garcia-Dominguez, V Sevillano, ... Oncogene 31 (10), 1287-1298, 2012 | 115 | 2012 |
| The molecular pathogenesis of Ewing sarcoma C Mackintosh, J Madoz-Gúrpide, JL Ordóñez, D Osuna, D Herrero-Martín Cancer biology & therapy 9 (9), 655-667, 2010 | 90 | 2010 |
| The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin JL Ordóñez, AT Amaral, AM Carcaboso, D Herrero-Martín, ... Oncotarget 6 (22), 18875, 2015 | 87 | 2015 |
| A Pivotal Role for Heat Shock Protein 90 in Ewing Sarcoma Resistance to Anti-Insulin-like Growth Factor 1 Receptor Treatment: In vitro and In vivo Study AS Martins, JL Ordonez, A Garcia-Sanchez, D Herrero, V Sevillano, ... Cancer research 68 (15), 6260-6270, 2008 | 85 | 2008 |
| WEE1 accumulation and deregulation of S-phase proteins mediate MLN4924 potent inhibitory effect on Ewing sarcoma cells C Mackintosh, DJ García-Domínguez, JL Ordóñez, A Ginel-Picardo, ... Oncogene 32 (11), 1441-1451, 2013 | 76 | 2013 |
| IGF1R signaling in Ewing sarcoma is shaped by clathrin-/caveolin-dependent endocytosis AS Martins, JL Ordóñez, AT Amaral, F Prins, G Floris, M Debiec-Rychter, ... PloS one 6 (5), e19846, 2011 | 63 | 2011 |
| The clinical relevance of molecular genetics in soft tissue sarcomas JL Ordóñez, D Osuna, DJ García-Domínguez, AT Amaral, AP Otero-Motta, ... Advances in Anatomic Pathology 17 (3), 162-181, 2010 | 47 | 2010 |
| Trabectedin efficacy in Ewing sarcoma is greatly increased by combination with anti-IGF signaling agents AT Amaral, C Garofalo, R Frapolli, MC Manara, C Mancarella, S Uboldi, ... Clinical Cancer Research 21 (6), 1373-1382, 2015 | 44 | 2015 |
| The calcium-sensing receptor is silenced by genetic and epigenetic mechanisms in unfavorable neuroblastomas and its reactivation induces ERK1/2-dependent apoptosis C Casalà, E Gil-Guiñón, JL Ordóñez, S Miguel-Queralt, E Rodríguez, ... Carcinogenesis 34 (2), 268-276, 2013 | 44 | 2013 |
| The CRISPR/Cas9 system efficiently reverts the tumorigenic ability of BCR/ABL in vitro and in a xenograft model of chronic myeloid leukemia I García-Tuñón, M Hernández-Sánchez, JL Ordoñez, V Alonso-Pérez, ... Oncotarget 8 (16), 26027, 2017 | 43 | 2017 |
| Characterization of human mesenchymal stem cells from ewing sarcoma patients. Pathogenetic implications AT Amaral, MC Manara, D Berghuis, JL Ordóñez, M Biscuola, ... PloS one 9 (2), e85814, 2014 | 40 | 2014 |
| Prevalence of human papillomavirus genotypes in cytologic abnormalities from unvaccinated women living in north‐western Spain ANAP OTERO‐MOTTA, JL Ordóñez, R GONZÁLEZ‐CELADOR, B Rivas, ... Apmis 119 (3), 204-215, 2011 | 36 | 2011 |
| Preclinical efficacy of endoglin-targeting antibody–drug conjugates for the treatment of Ewing sarcoma P Puerto-Camacho, AT Amaral, SE Lamhamedi-Cherradi, BA Menegaz, ... Clinical Cancer Research 25 (7), 2228-2240, 2019 | 34 | 2019 |
| CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del (11q) CLL cells to dual BCR and PARP inhibition M Quijada-Álamo, M Hernández-Sánchez, V Alonso-Pérez, ... Leukemia 34 (6), 1599-1612, 2020 | 31 | 2020 |
| Automatically enhanced OCT scans of the retina: a proof of concept study S Apostolopoulos, J Salas, JLP Ordóñez, SS Tan, C Ciller, A Ebneter, ... Scientific reports 10 (1), 7819, 2020 | 27 | 2020 |
| Cyclin D3 gene amplification in bladder carcinoma in situ A Lopez-Beltran, JL Ordóñez, AP Otero, A Blanca, V Sevillano, ... Virchows Archiv 457, 555-561, 2010 | 24 | 2010 |
| ETV6/RUNX1 Fusion Gene Abrogation Decreases the Oncogenicity of Tumour Cells in a Preclinical Model of Acute Lymphoblastic Leukaemia A Montaño, JL Ordoñez, V Alonso-Pérez, J Hernández-Sánchez, ... Cells 9 (1), 215, 2020 | 22 | 2020 |
