CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients S Su, B Hu, J Shao, B Shen, J Du, Y Du, J Zhou, L Yu, L Zhang, F Chen, ... Scientific reports 6 (1), 20070, 2016 | 347 | 2016 |
Efficient in vivo deletion of a large imprinted lncRNA by CRISPR/Cas9 J Han, J Zhang, L Chen, B Shen, J Zhou, B Hu, Y Du, PH Tate, X Huang, ... RNA biology 11 (7), 829-835, 2014 | 194 | 2014 |
Efficient generation of gene-modified pigs via injection of zygote with Cas9/sgRNA Y Wang, Y Du, B Shen, X Zhou, J Li, Y Liu, J Wang, J Zhou, B Hu, N Kang, ... Scientific reports 5 (1), 8256, 2015 | 138 | 2015 |
The role of miRNAs in colorectal cancer progression and chemoradiotherapy N Zhang, X Hu, Y Du, J Du Biomedicine & Pharmacotherapy 134, 111099, 2021 | 104 | 2021 |
Efficient generation of gene‐modified pigs harboring precise orthologous human mutation via CRISPR/Cas9‐induced homology‐directed repair in zygotes X Zhou, L Wang, Y Du, F Xie, L Li, Y Liu, C Liu, S Wang, S Zhang, ... Human mutation 37 (1), 110-118, 2016 | 86 | 2016 |
Cilia loss sensitizes cells to transformation by activating the mevalonate pathway YZ Deng, Z Cai, S Shi, H Jiang, YR Shang, N Ma, JJ Wang, DX Guan, ... Journal of Experimental Medicine 215 (1), 177-195, 2018 | 56 | 2018 |
A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation X Gao, W Ma, J Nie, C Zhang, J Zhang, G Yao, J Han, J Xu, B Hu, Y Du, ... Cell death & disease 6 (1), e1610-e1610, 2015 | 42 | 2015 |
Efficient generation of B2m-null pigs via injection of zygote with TALENs Y Wang, Y Du, X Zhou, L Wang, J Li, F Wang, Z Huang, X Huang, H Wei Scientific Reports 6 (1), 38854, 2016 | 39 | 2016 |
A convenient Cas9-based conditional knockout strategy for simultaneously targeting multiple genes in mouse J Chen, Y Du, X He, X Huang, YS Shi Scientific reports 7 (1), 517, 2017 | 28 | 2017 |
Integrate analysis of the promote function of Cell division cycle-associated protein family to pancreatic adenocarcinoma C Xing, Z Wang, Y Zhu, C Zhang, M Liu, X Hu, W Chen, Y Du International journal of medical sciences 18 (3), 672, 2021 | 26 | 2021 |
Efficient knockin mouse generation by ssDNA oligonucleotides and zinc-finger nuclease assisted homologous recombination in zygotes B Shen, X Zhang, Y Du, J Wang, J Gong, X Zhang, PH Tate, H Li, ... PloS one 8 (10), e77696, 2013 | 25 | 2013 |
Exocyst controls exosome biogenesis via Rab11a S Bai, W Hou, Y Yao, J Meng, Y Wei, F Hu, X Hu, J Wu, N Zhang, R Xu, ... Molecular Therapy-Nucleic Acids 27, 535-546, 2022 | 16 | 2022 |
A lipidomics study reveals hepatic lipid signatures associating with deficiency of the LDL receptor in a rat model HY Wang, C Quan, C Hu, B Xie, Y Du, L Chen, W Yang, L Yang, Q Chen, ... Biology open 5 (7), 979-986, 2016 | 16 | 2016 |
Functions of the Vasa gene in Schistosoma japonicum as assessed by RNA interference S He, L Zhu, F Liu, Q Liu, Y Shao, M Hua, H Ding, W Shao, Y Du, X Hou, ... Gene 638, 13-19, 2018 | 13 | 2018 |
Separase phosphosite mutation leads to genome instability and primordial germ cell depletion during oogenesis J Xu, M Wang, X Gao, B Hu, Y Du, J Zhou, X Tian, X Huang PloS one 6 (4), e18763, 2011 | 13 | 2011 |
Respiratory mucosal immunity: kinetics of secretory immunoglobulin A in sputum and throat swabs from COVID-19 patients and vaccine recipients C Ren, Y Gao, C Zhang, C Zhou, Y Hong, M Qu, Z Zhao, Y Du, L Yang, ... Frontiers in Microbiology 13, 782421, 2022 | 11 | 2022 |
JQ1, a bromodomain inhibitor, suppresses Th17 effectors by blocking p300‐mediated acetylation of RORγt X Wang, Y Yang, D Ren, Y Xia, W He, Q Wu, J Zhang, M Liu, Y Du, C Ren, ... British Journal of Pharmacology 177 (13), 2959-2973, 2020 | 11 | 2020 |
Tyrosine kinase 4 is involved in the reproduction of the platyhelminth parasite Schistosoma japonicum H Ding, F Liu, L Zhu, F Wu, Q Liu, S He, W Shao, Y Du, C Ren, J Shen, ... Parasites & vectors 10, 1-12, 2017 | 11 | 2017 |
Orai-IGFBP3 signaling complex regulates high-glucose exposure-induced increased proliferation, permeability, and migration of human coronary artery endothelial cells S Bai, Y Wei, W Hou, YH Yao, J Zhu, X Hu, W Chen, Y Du, W He, B Shen, ... BMJ Open Diabetes Research and Care 8 (1), e001400, 2020 | 10 | 2020 |
Progress of CRISPR-Cas13 mediated live-cell RNA imaging and detection of RNA-protein interactions H Cao, Y Wang, N Zhang, S Xia, P Tian, L Lu, J Du, Y Du Frontiers in Cell and Developmental Biology 10, 866820, 2022 | 9 | 2022 |