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Motomi Osato
Motomi Osato
Cancer Science Institute, National University of Singapore
Verified email at nus.edu.sg
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Cited by
Year
Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development
I Taniuchi, M Osato, T Egawa, MJ Sunshine, SC Bae, T Komori, Y Ito, ...
Cell 111 (5), 621-633, 2002
8642002
Biallelic and Heterozygous Point Mutations in the Runt Domain of theAML1/PEBP2B Gene Associated With Myeloblastic Leukemias
M Osato, N Asou, E Abdalla, K Hoshino, H Yamasaki, T Okubo, ...
Blood, The Journal of the American Society of Hematology 93 (6), 1817-1824, 1999
4841999
In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms …
J Michaud, F Wu, M Osato, GM Cottles, M Yanagida, N Asou, ...
Blood, The Journal of the American Society of Hematology 99 (4), 1364-1372, 2002
4372002
MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis
CM Koh, M Bezzi, DHP Low, WX Ang, SX Teo, FPH Gay, M Al-Haddawi, ...
Nature 523 (7558), 96-100, 2015
3742015
Point mutations in the RUNX1/AML1 gene: another actor in RUNX leukemia
M Osato
Oncogene 23 (24), 4284-4296, 2004
3492004
Heterozygous PU. 1 mutations are associated with acute myeloid leukemia
BU Mueller, T Pabst, M Osato, N Asou, LM Johansen, MD Minden, ...
Blood, The Journal of the American Society of Hematology 100 (3), 998-1007, 2002
3012002
RUNX3 attenuates β-catenin/T cell factors in intestinal tumorigenesis
K Ito, ACB Lim, M Salto-Tellez, L Motoda, M Osato, LSH Chuang, ...
Cancer cell 14 (3), 226-237, 2008
2552008
Requirement of Runx1/AML1/PEBP2αB for the generation of haematopoietic cells from endothelial cells
T Yokomizo, M Ogawa, M Osato, T Kanno, H Yoshida, T Fujimoto, ...
Genes to Cells 6 (1), 13-23, 2001
2102001
Functional analysis of RUNX2 mutations in Japanese patients with cleidocranial dysplasia demonstrates novel genotype-phenotype correlations
T Yoshida, H Kanegane, M Osato, M Yanagida, T Miyawaki, Y Ito, ...
The American Journal of Human Genetics 71 (4), 724-738, 2002
2072002
Identification of stem cells in the epithelium of the stomach corpus and antrum of mice
J Matsuo, S Kimura, A Yamamura, CP Koh, MZ Hossain, DL Heng, ...
Gastroenterology 152 (1), 218-231. e14, 2017
1472017
Integrative analysis of RUNX1 downstream pathways and target genes
J Michaud, KM Simpson, R Escher, K Buchet-Poyau, T Beissbarth, ...
BMC genomics 9, 1-17, 2008
1452008
Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis
B Jacob, M Osato, N Yamashita, CQ Wang, I Taniuchi, DR Littman, ...
Blood, The Journal of the American Society of Hematology 115 (8), 1610-1620, 2010
1402010
PRL-3 initiates tumor angiogenesis by recruiting endothelial cells in vitro and in vivo
K Guo, J Li, H Wang, M Osato, JP Tang, SY Quah, BQ Gan, Q Zeng
Cancer research 66 (19), 9625-9635, 2006
1172006
A Runx1 Intronic Enhancer Marks Hemogenic Endothelial Cells and Hematopoietic Stem Cells
CEL Ng, T Yokomizo, N Yamashita, B Cirovic, H Jin, Z Wen, Y Ito, M Osato
Stem cells 28 (10), 1869-1881, 2010
1062010
Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects
CQ Wang, V Krishnan, LS Tay, DWL Chin, CP Koh, JY Chooi, GSS Nah, ...
Cell reports 8 (3), 767-782, 2014
1032014
Requirement for Runx proteins in IgA class switching acting downstream of TGF-β1 and retinoic acid signaling
K Watanabe, M Sugai, Y Nambu, M Osato, T Hayashi, M Kawaguchi, ...
The Journal of Immunology 184 (6), 2785-2792, 2010
1032010
Runx1 is involved in primitive erythropoiesis in the mouse
T Yokomizo, K Hasegawa, H Ishitobi, M Osato, M Ema, Y Ito, M Yamamoto, ...
Blood, The Journal of the American Society of Hematology 111 (8), 4075-4080, 2008
1002008
Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model
M Iwasaki, T Kuwata, Y Yamazaki, NA Jenkins, NG Copeland, M Osato, ...
Blood 105 (2), 784-793, 2005
982005
Runx1 Protects Hematopoietic Stem/Progenitor Cells from Oncogenic Insult
L Motoda, M Osato, N Yamashita, B Jacob, LQ Chen, M Yanagida, H Ida, ...
Stem cells 25 (12), 2976-2986, 2007
962007
The ability of MLL to bind RUNX1 and methylate H3K4 at PU. 1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations
G Huang, X Zhao, L Wang, S Elf, H Xu, X Zhao, G Sashida, Y Zhang, Y Liu, ...
Blood, The Journal of the American Society of Hematology 118 (25), 6544-6552, 2011
892011
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