Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins R Prakash, Y Zhang, W Feng, M Jasin Cold Spring Harbor perspectives in biology 7 (4), a016600, 2015 | 835 | 2015 |
An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway Y Zhang, M Jasin Nature structural & molecular biology 18 (1), 80-84, 2011 | 328 | 2011 |
Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks EY Shim, WH Chung, ML Nicolette, Y Zhang, M Davis, Z Zhu, TT Paull, ... The EMBO journal 29 (19), 3370-3380, 2010 | 292 | 2010 |
RSC mobilizes nucleosomes to improve accessibility of repair machinery to the damaged chromatin EY Shim, SJ Hong, JH Oum, Y Yanez, Y Zhang, SE Lee Molecular and cellular biology 27 (5), 1602-1613, 2007 | 223 | 2007 |
Role of Dnl4–Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination Y Zhang, ML Hefferin, L Chen, EY Shim, HM Tseng, Y Kwon, P Sung, ... Nature structural & molecular biology 14 (7), 639-646, 2007 | 200 | 2007 |
Saccharomyces cerevisiae ATM orthologue suppresses break-induced chromosome translocations K Lee, Y Zhang, SE Lee Nature 454 (7203), 543-546, 2008 | 91 | 2008 |
PARP1 is required for chromosomal translocations J Wray, EA Williamson, SB Singh, Y Wu, CR Cogle, DM Weinstock, ... Blood, The Journal of the American Society of Hematology 121 (21), 4359-4365, 2013 | 88 | 2013 |
Distinct genetic control of homologous recombination repair of Cas9-induced double-strand breaks, nicks and paired nicks LEM Vriend, R Prakash, CC Chen, F Vanoli, F Cavallo, Y Zhang, M Jasin, ... Nucleic acids research 44 (11), 5204-5217, 2016 | 72 | 2016 |
Regulation of repair choice: Cdk1 suppresses recruitment of end joining factors at DNA breaks Y Zhang, EY Shim, M Davis, SE Lee DNA repair 8 (10), 1235-1241, 2009 | 72 | 2009 |
Patient-specific mutations impair BESTROPHIN1’s essential role in mediating Ca2+-dependent Cl- currents in human RPE Y Li, Y Zhang, Y Xu, A Kittredge, N Ward, S Chen, SH Tsang, T Yang Elife 6, e29914, 2017 | 53 | 2017 |
SSX2IP promotes metastasis and chemotherapeutic resistance of hepatocellular carcinoma P Li, Y Lin, Y Zhang, Z Zhu, K Huo Journal of translational medicine 11, 1-9, 2013 | 33 | 2013 |
Investigation and restoration of BEST1 activity in patient-derived RPEs with dominant mutations C Ji, Y Li, A Kittredge, A Hopiavuori, N Ward, P Yao, Y Fukuda, Y Zhang, ... Scientific reports 9 (1), 19026, 2019 | 32 | 2019 |
ATP activates bestrophin ion channels through direct interaction Y Zhang, A Kittredge, N Ward, C Ji, S Chen, T Yang Nature communications 9 (1), 3126, 2018 | 30 | 2018 |
Molecular cloning and characterization of CT120, a novel membrane-associated gene involved in amino acid transport and glutathione metabolism X He, Y Di, J Li, Y Xie, Y Tang, F Zhang, L Wei, Y Zhang, W Qin, K Huo, ... Biochemical and biophysical research communications 297 (3), 528-536, 2002 | 30 | 2002 |
Structural and functional characterization of the bestrophin-2 anion channel AP Owji, Q Zhao, C Ji, A Kittredge, A Hopiavuori, Z Fu, N Ward, OB Clarke, ... Nature structural & molecular biology 27 (4), 382-391, 2020 | 28 | 2020 |
Biallelic targeting of expressed genes in mouse embryonic stem cells using the Cas9 system Y Zhang, F Vanoli, JR LaRocque, PM Krawczyk, M Jasin Methods 69 (2), 171-178, 2014 | 28 | 2014 |
EXO1 suppresses double-strand break induced homologous recombination between diverged sequences in mammalian cells CC Chen, E Avdievich, Y Zhang, Y Zhang, K Wei, K Lee, W Edelmann, ... DNA repair 57, 98-106, 2017 | 18 | 2017 |
Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations C Ji, A Kittredge, A Hopiavuori, N Ward, S Chen, Y Fukuda, Y Zhang, ... Communications Biology 2 (1), 240, 2019 | 17 | 2019 |
Differentiation, maintenance, and analysis of human retinal pigment epithelium cells: a disease-in-a-dish model for BEST1 mutations A Kittredge, C Ji, Y Zhang, T Yang JoVE (Journal of Visualized Experiments), e57791, 2018 | 13 | 2018 |
Distinct expression requirements and rescue strategies for BEST1 loss- and gain-of-function mutations Q Zhao, Y Kong, A Kittredge, Y Li, Y Shen, Y Zhang, SH Tsang, T Yang Elife 10, e67622, 2021 | 12 | 2021 |