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Yu Zhang
Yu Zhang
Verified email at cumc.columbia.edu
Title
Cited by
Cited by
Year
Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteins
R Prakash, Y Zhang, W Feng, M Jasin
Cold Spring Harbor perspectives in biology 7 (4), a016600, 2015
8352015
An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway
Y Zhang, M Jasin
Nature structural & molecular biology 18 (1), 80-84, 2011
3282011
Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks
EY Shim, WH Chung, ML Nicolette, Y Zhang, M Davis, Z Zhu, TT Paull, ...
The EMBO journal 29 (19), 3370-3380, 2010
2922010
RSC mobilizes nucleosomes to improve accessibility of repair machinery to the damaged chromatin
EY Shim, SJ Hong, JH Oum, Y Yanez, Y Zhang, SE Lee
Molecular and cellular biology 27 (5), 1602-1613, 2007
2232007
Role of Dnl4–Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination
Y Zhang, ML Hefferin, L Chen, EY Shim, HM Tseng, Y Kwon, P Sung, ...
Nature structural & molecular biology 14 (7), 639-646, 2007
2002007
Saccharomyces cerevisiae ATM orthologue suppresses break-induced chromosome translocations
K Lee, Y Zhang, SE Lee
Nature 454 (7203), 543-546, 2008
912008
PARP1 is required for chromosomal translocations
J Wray, EA Williamson, SB Singh, Y Wu, CR Cogle, DM Weinstock, ...
Blood, The Journal of the American Society of Hematology 121 (21), 4359-4365, 2013
882013
Distinct genetic control of homologous recombination repair of Cas9-induced double-strand breaks, nicks and paired nicks
LEM Vriend, R Prakash, CC Chen, F Vanoli, F Cavallo, Y Zhang, M Jasin, ...
Nucleic acids research 44 (11), 5204-5217, 2016
722016
Regulation of repair choice: Cdk1 suppresses recruitment of end joining factors at DNA breaks
Y Zhang, EY Shim, M Davis, SE Lee
DNA repair 8 (10), 1235-1241, 2009
722009
Patient-specific mutations impair BESTROPHIN1’s essential role in mediating Ca2+-dependent Cl- currents in human RPE
Y Li, Y Zhang, Y Xu, A Kittredge, N Ward, S Chen, SH Tsang, T Yang
Elife 6, e29914, 2017
532017
SSX2IP promotes metastasis and chemotherapeutic resistance of hepatocellular carcinoma
P Li, Y Lin, Y Zhang, Z Zhu, K Huo
Journal of translational medicine 11, 1-9, 2013
332013
Investigation and restoration of BEST1 activity in patient-derived RPEs with dominant mutations
C Ji, Y Li, A Kittredge, A Hopiavuori, N Ward, P Yao, Y Fukuda, Y Zhang, ...
Scientific reports 9 (1), 19026, 2019
322019
ATP activates bestrophin ion channels through direct interaction
Y Zhang, A Kittredge, N Ward, C Ji, S Chen, T Yang
Nature communications 9 (1), 3126, 2018
302018
Molecular cloning and characterization of CT120, a novel membrane-associated gene involved in amino acid transport and glutathione metabolism
X He, Y Di, J Li, Y Xie, Y Tang, F Zhang, L Wei, Y Zhang, W Qin, K Huo, ...
Biochemical and biophysical research communications 297 (3), 528-536, 2002
302002
Structural and functional characterization of the bestrophin-2 anion channel
AP Owji, Q Zhao, C Ji, A Kittredge, A Hopiavuori, Z Fu, N Ward, OB Clarke, ...
Nature structural & molecular biology 27 (4), 382-391, 2020
282020
Biallelic targeting of expressed genes in mouse embryonic stem cells using the Cas9 system
Y Zhang, F Vanoli, JR LaRocque, PM Krawczyk, M Jasin
Methods 69 (2), 171-178, 2014
282014
EXO1 suppresses double-strand break induced homologous recombination between diverged sequences in mammalian cells
CC Chen, E Avdievich, Y Zhang, Y Zhang, K Wei, K Lee, W Edelmann, ...
DNA repair 57, 98-106, 2017
182017
Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations
C Ji, A Kittredge, A Hopiavuori, N Ward, S Chen, Y Fukuda, Y Zhang, ...
Communications Biology 2 (1), 240, 2019
172019
Differentiation, maintenance, and analysis of human retinal pigment epithelium cells: a disease-in-a-dish model for BEST1 mutations
A Kittredge, C Ji, Y Zhang, T Yang
JoVE (Journal of Visualized Experiments), e57791, 2018
132018
Distinct expression requirements and rescue strategies for BEST1 loss- and gain-of-function mutations
Q Zhao, Y Kong, A Kittredge, Y Li, Y Shen, Y Zhang, SH Tsang, T Yang
Elife 10, e67622, 2021
122021
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