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Jacqueline Ernest, PhD
Jacqueline Ernest, PhD
Verified email at ucsf.edu
Title
Cited by
Cited by
Year
Optimizing hydroxychloroquine dosing for patients with COVID‐19: an integrative modeling approach for effective drug repurposing
M Garcia‐Cremades, BP Solans, E Hughes, JP Ernest, E Wallender, ...
Clinical Pharmacology & Therapeutics 108 (2), 253-263, 2020
1292020
Development of new tuberculosis drugs: translation to regimen composition for drug-sensitive and multidrug-resistant tuberculosis
JP Ernest, N Strydom, Q Wang, N Zhang, E Nuermberger, V Dartois, ...
Annual review of pharmacology and toxicology 61, 495-516, 2021
332021
Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders
B Yi, A Jahangir, AK Evans, D Briggs, K Ravina, J Ernest, AB Farimani, ...
PLoS One 12 (7), e0180319, 2017
222017
Lesion penetration and activity limit the utility of second-line injectable agents in pulmonary tuberculosis
JP Ernest, J Sarathy, N Wang, F Kaya, MD Zimmerman, N Strydom, ...
Antimicrobial agents and chemotherapy 65 (10), 10.1128/aac. 00506-21, 2021
152021
A rabbit model to study antibiotic penetration at the site of infection for nontuberculous mycobacterial lung disease: macrolide case study
F Kaya, JP Ernest, K LoMauro, M Gengenbacher, A Madani, WW Aragaw, ...
Antimicrobial agents and chemotherapy 66 (3), e02212-21, 2022
142022
Pharmacometrics in tuberculosis: progress and opportunities
JJ Wilkins, EM Svensson, JP Ernest, RM Savic, USH Simonsson, ...
International Journal of Antimicrobial Agents 60 (3), 106620, 2022
72022
Comparative efficacy of rifapentine alone and in combination with isoniazid for latent tuberculosis infection: a translational pharmacokinetic-pharmacodynamic modeling study
KK Radtke, JP Ernest, N Zhang, NC Ammerman, E Nuermberger, ...
Antimicrobial agents and chemotherapy 65 (12), 10.1128/aac. 01705-21, 2021
72021
Optimizing hydroxychloroquine dosing for patients with COVID-19: an integrative modeling approach for effective drug repurposing
M Garcia-Cremades, BP Solans, E Hughes, JP Ernest, E Wallender, ...
Clin Pharmacol Ther. https://doi. org/10.1002/cpt, 1856
61856
Lung microenvironments harbor Mycobacterium tuberculosis phenotypes with distinct treatment responses
ND Walter, JP Ernest, C Dide-Agossou, AA Bauman, ME Ramey, ...
Antimicrobial Agents and Chemotherapy 67 (9), e00284-23, 2023
42023
Translational predictions of phase 2a first-in-patient efficacy studies for antituberculosis drugs
JP Ernest, JJN Goh, N Strydom, Q Wang, RC van Wijk, N Zhang, ...
European Respiratory Journal 62 (2), 2023
12023
LIMITED PENETRATION AND EFFICACY OF AMINOGLYCOSIDES IN LESIONS OF TUBERCULOSIS: A TRANSLATIONAL SITE-OF-ACTION PKPD MODELING STUDY.
J Ernest, N Strydom, J Sarathy, M Zimmerman, V Dartois, R Savic
CLINICAL PHARMACOLOGY & THERAPEUTICS 109, S28-S28, 2021
12021
PREDICTING THE EARLY BACTERICIDAL ACTIVITY (EBA) OF TUBERCULOSIS (TB) DRUGS FOR THE PHASE IIA FIRST-IN-PATIENTS STUDIES.
N Zhang, N Strydom, Q Wang, J Ernest, E Nuermberger, R Savic
CLINICAL PHARMACOLOGY & THERAPEUTICS 107, S83-S83, 2020
12020
It's That Time of Year-Give Yourself the Gift of SCIENCE!
J Ernest
CLINICAL PHARMACOLOGY & THERAPEUTICS 114 (6), 1161-1161, 2023
2023
Translating Nonclinical Findings to Prioritize Sterilizing Multi-Drug Regimens for the Treatment of Tuberculosis
J Ernest
University of California, San Francisco, 2022
2022
Response to “Quantitative Clinical Pharmacology INPUT to SARS‐CoV‐2 Therapeutics Should be Based on Robust Data”
M Garcia‐Cremades, BP Solans, E Hughes, JP Ernest, E Wallender, ...
Clinical pharmacology and therapeutics 108 (2), 189, 2020
2020
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Articles 1–15