| Langerhans cells—programmed by the epidermis K Clayton, AF Vallejo, J Davies, S Sirvent, ME Polak Frontiers in immunology 8, 316131, 2017 | 163 | 2017 |
| Genomic programming of IRF4-expressing human Langerhans cells S Sirvent, AF Vallejo, J Davies, K Clayton, Z Wu, J Woo, J Riddell, ... Nature Communications 11 (1), 313, 2020 | 23 | 2020 |
| Gene expression signatures in tuberculosis have greater overlap with autoimmune diseases than with infectious diseases K Clayton, ME Polak, CH Woelk, P Elkington American journal of respiratory and critical care medicine 196 (5), 655-656, 2017 | 23 | 2017 |
| Machine learning applied to atopic dermatitis transcriptome reveals distinct therapy‐dependent modification of the keratinocyte immunophenotype K Clayton, A Vallejo, S Sirvent, J Davies, G Porter, IC Reading, F Lim, ... British Journal of Dermatology 184 (5), 913-922, 2021 | 14 | 2021 |
| An IRF1-IRF4 toggle-switch controls tolerogenic and immunogenic transcriptional programming in human langerhans cells J Davies, AF Vallejo, S Sirvent, G Porter, K Clayton, Y Qumbelo, P Stumpf, ... Frontiers in Immunology 12, 665312, 2021 | 13 | 2021 |
| Single cell transcriptomic analysis indentifies Langerhans cells immunocompetency is critical for IDO1-dependent ability to induce tolerogenic T cells J Davies, S Sirvent, AF Vallejo, K Clayton, G Porter, P Stumpf, J West, ... bioRxiv, 2019.12. 20.884130, 2019 | 5 | 2019 |
| Langerhans Cells-Programmed by the Epidermis. Front Immunol. 2017; 8: 1676 K Clayton, AF Vallejo, J Davies, S Sirvent, ME Polak Epub 2017/12/15. doi: 10.3389/fimmu. 2017.01676. PubMed PMID: 29238347, 2017 | 5 | 2017 |
| Impaired expression of metallothioneins contributes to allergen-induced inflammation in patients with atopic dermatitis S Sirvent, AF Vallejo, E Corden, Y Teo, J Davies, K Clayton, EG Seaby, ... Nature Communications 14 (1), 2880, 2023 | 4 | 2023 |
| Skin programming of inflammatory responses to Staphylococcus aureus is compartmentalized according to epidermal keratinocyte differentiation status K Clayton, DJ Holbrook, A Vallejo, G Porter, S Sirvent, J Davies, J Pople, ... British Journal of Dermatology 188 (3), 396-406, 2023 | 4 | 2023 |
| Transcriptional programming of immunoregulatory responses in human Langerhans cells J Davies, S Sirvent, AF Vallejo, K Clayton, G Douilhet, PS Keeler, J West, ... Frontiers in Immunology 13, 892254, 2022 | 1 | 2022 |
| TNFα SIGNALLING IN THE CUTANEOUS IMMUNE NETWORK INSTRUCTS LOCAL Th17 ALLERGEN-SPECIFIC INFLAMMATORY RESPONSES IN ATOPIC DERMATITIS S Sirvent, A Vallejo, E Corden, Y Teo, J Davies, K Clayton, E Seaby, C Lai, ... medRxiv, 2021.10. 07.21264714, 2021 | 1 | 2021 |
| Genomic programming of antigen cross-presentation in IRF4-expressing human Langerhans cells ME Polak, S Sirvent, K Clayton, J Davies, AF Vallejo, Z Wu, J Woo, ... bioRxiv, 541383, 2019 | 1 | 2019 |
| Machine learning applied to the atopic dermatitis transcriptome reveals distinct therapy-dependent modification of the keratinocyte immunophenotype K Clayton, J Davies, G Porter, S Sirvent, A Vallejo, FL Lim, ... BRITISH JOURNAL OF DERMATOLOGY 187 (1), E14-E15, 2022 | | 2022 |
| Langerhans cells immunocompetency is critical for indoleamine 2, 3-dioxygenase-dependent ability to induce tolerogenic T cells J Davies, S Sirvent, A Vallejo, K Clayton, G Porter, P Stumpf, J West, ... BRITISH JOURNAL OF DERMATOLOGY 187 (1), E9-E9, 2022 | | 2022 |
| Langerhans cell exhaustion in the context of local inflammation perpetuates cutaneous inflammatory responses to allergen in atopic dermatitis patients S Sirvent, J Davies, A Vallejo, E Corden, Y Teo, K Clayton, S Horswill, ... BRITISH JOURNAL OF DERMATOLOGY 187 (1), E7-E7, 2022 | | 2022 |
| Genetic Algorithm with Rank Selection optimises robust parameter estimation for systems biology models G Douilhet, M Niranjan, A Vallejo, K Clayton, J Davies, S Sirvent, J Pople, ... bioRxiv, 2022.02. 22.481394, 2022 | | 2022 |
| TNF signalling fine-tunes Langerhans cell transcriptional programmes mediating adaptive immunity J Davies, AF Vallejo, S Sirvent, G Porter, K Clayton, Y Qumbelo, P Stumpf, ... bioRxiv, 2021.02. 07.430111, 2021 | | 2021 |
| Investigating the crosstalk between structural and immune components of human skin to understand pathogen sensing in cutaneous health and inflammation K Clayton University of Southampton, 2021 | | 2021 |
| Langerhans cells immunocompetency is critical for IDO1-dependent ability to induce tolerogenic T cells J Davies, S Sirvent, AF Vallejo, K Clayton, G Porter, P Stumpf, J West, ... | | 2019 |
| Single cell transcriptomic analysis identifies a subpopulation of immunocompetent Langerhans cells with ability to induce tolerogenic T cells in steady state primary human skin. J Davies, A Vallejo-Pulido, S Sirvent, K Clayton, J West, M Ardern-Jones, ... EUROPEAN JOURNAL OF IMMUNOLOGY 49, 11-12, 2019 | | 2019 |
