| Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome T Tanaka, J Yamamoto, S Iwasaki, H Asaba, H Hamura, Y Ikeda, ... Proceedings of the National Academy of Sciences 100 (26), 15924-15929, 2003 | 1074 | 2003 |
| Rabbit very low density lipoprotein receptor: a low density lipoprotein receptor-like protein with distinct ligand specificity. S Takahashi, Y Kawarabayasi, T Nakai, J Sakai, T Yamamoto Proceedings of the National Academy of Sciences 89 (19), 9252-9256, 1992 | 705 | 1992 |
| Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment J Sakai, EA Duncan, RB Rawson, X Hua, MS Brown, JL Goldstein Cell 85 (7), 1037-1046, 1996 | 673 | 1996 |
| Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs RB Rawson, NG Zelenski, D Nijhawan, J Ye, J Sakai, MT Hasan, ... Molecular cell 1 (1), 47-57, 1997 | 588 | 1997 |
| Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells J Sakai, RB Rawson, PJ Espenshade, D Cheng, AC Seegmiller, ... Molecular cell 2 (4), 505-514, 1998 | 527 | 1998 |
| Human apolipoprotein E receptor 2: a novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain DH Kim, H Iijima, K Goto, J Sakai, H Ishii, HJ Kim, H Suzuki, H Kondo, ... Journal of Biological Chemistry 271 (14), 8373-8380, 1996 | 485 | 1996 |
| Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion T Fujino, H Asaba, MJ Kang, Y Ikeda, H Sone, S Takada, DH Kim, RX Ioka, ... Proceedings of the National Academy of Sciences 100 (1), 229-234, 2003 | 473 | 2003 |
| Cleavage of sterol regulatory element binding proteins (SREBPs) by CPP32 during apoptosis. X Wang, NG Zelenski, J Yang, J Sakai, MS Brown, JL Goldstein The EMBO journal 15 (5), 1012-1020, 1996 | 420 | 1996 |
| cDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolism EG Lund, TA Kerr, J Sakai, WP Li, DW Russell Journal of Biological Chemistry 273 (51), 34316-34327, 1998 | 388 | 1998 |
| Structure, chromosome location, and expression of the human very low density lipoprotein receptor gene. J Sakai, A Hoshino, S Takahashi, Y Miura, H Ishii, H Suzuki, ... Journal of Biological Chemistry 269 (3), 2173-2182, 1994 | 347 | 1994 |
| Transcriptional and epigenetic control of brown and beige adipose cell fate and function T Inagaki, J Sakai, S Kajimura Nature reviews Molecular cell biology 17 (8), 480-495, 2016 | 326 | 2016 |
| Identification of complexes between the COOH-terminal domains of sterol regulatory element-binding proteins (SREBPs) and SREBP cleavage-activating protein J Sakai, A Nohturfft, D Cheng, YK Ho, MS Brown, JL Goldstein Journal of Biological Chemistry 272 (32), 20213-20221, 1997 | 316 | 1997 |
| Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein: evidence from in vivo competition studies J Sakai, A Nohturfft, JL Goldstein, MS Brown Journal of Biological Chemistry 273 (10), 5785-5793, 1998 | 293 | 1998 |
| A small molecule that blocks fat synthesis by inhibiting the activation of SREBP S Kamisuki, Q Mao, L Abu-Elheiga, Z Gu, A Kugimiya, Y Kwon, ... Chemistry & biology 16 (8), 882-892, 2009 | 273 | 2009 |
| Angiopoietin-related growth factor antagonizes obesity and insulin resistance Y Oike, M Akao, K Yasunaga, T Yamauchi, T Morisada, Y Ito, T Urano, ... Nature medicine 11 (4), 400-408, 2005 | 272 | 2005 |
| Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A I Mimura, M Nangaku, Y Kanki, S Tsutsumi, T Inoue, T Kohro, ... Molecular and cellular biology 32 (15), 3018-3032, 2012 | 258 | 2012 |
| Regulated Cleavage of Sterol Regulatory Element Binding Proteins Requires Sequences on Both Sides of the Endoplasmic Reticulum Membrane (∗) X Hua, J Sakai, MS Brown, JL Goldstein Journal of Biological Chemistry 271 (17), 10379-10384, 1996 | 250 | 1996 |
| Cleavage site for sterol-regulated protease localized to a Leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2 EA Duncan, MS Brown, JL Goldstein, J Sakai Journal of Biological Chemistry 272 (19), 12778-12785, 1997 | 244 | 1997 |
| The very low-density lipoprotein (VLDL) receptor: characterization and functions as a peripheral lipoprotein receptor S Takahashi, J Sakai, T Fujino, H Hattori, Y Zenimaru, J Suzuki, ... Journal of atherosclerosis and thrombosis 11 (4), 200-208, 2004 | 231 | 2004 |
| The peroxisome proliferator-activated receptor γ/retinoid X receptor α heterodimer targets the histone modification enzyme PR-Set7/Setd8 gene and regulates adipogenesis through … K Wakabayashi, M Okamura, S Tsutsumi, NS Nishikawa, T Tanaka, ... Molecular and cellular biology 29 (13), 3544-3555, 2009 | 222 | 2009 |
Hiroyuki AburataniRCAST, The University of TokyoVerified email at umin.ac.jp
