| Targeting tumor-intrinsic hexosamine biosynthesis sensitizes pancreatic cancer to anti-PD1 therapy NS Sharma, VK Gupta, VT Garrido, R Hadad, BC Durden, K Kesh, B Giri, ... The Journal of clinical investigation 130 (1), 451-465, 2020 | 152 | 2020 |
| Inactivation of cancer-associated-fibroblasts disrupts oncogenic signaling in pancreatic cancer cells and promotes its regression P Dauer, X Zhao, VK Gupta, N Sharma, K Kesh, P Gnamlin, V Dudeja, ... Cancer research 78 (5), 1321-1333, 2018 | 106 | 2018 |
| ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining “stemness” P Dauer, NS Sharma, VK Gupta, B Durden, R Hadad, S Banerjee, ... Cell death & disease 10 (2), 132, 2019 | 89 | 2019 |
| O-GlcNAc modification of Sox2 regulates self-renewal in pancreatic cancer by promoting its stability NS Sharma, VK Gupta, P Dauer, K Kesh, R Hadad, B Giri, A Chandra, ... Theranostics 9 (12), 3410, 2019 | 55 | 2019 |
| NFκB-Mediated Invasiveness in CD133+ Pancreatic TICs Is Regulated by Autocrine and Paracrine Activation of IL1 Signaling. BS Nomura A1,2, Gupta VK1, Dauer P1,3, Sharma NS1,4, Dudeja V1, Merchant N1 ... Molecular Cancer Research, 2018 | 55 | 2018 |
| Metastasis and chemoresistance in CD133 expressing pancreatic cancer cells are dependent on their lipid raft integrity VK Gupta, NS Sharma, K Kesh, P Dauer, A Nomura, B Giri, V Dudeja, ... Cancer letters 439, 101-112, 2018 | 53 | 2018 |
| Hypoxia-driven oncometabolite L-2HG maintains stemness-differentiation balance and facilitates immune evasion in pancreatic cancer VK Gupta, NS Sharma, B Durden, VT Garrido, K Kesh, D Edwards, ... Cancer research 81 (15), 4001-4013, 2021 | 47 | 2021 |
| GRP 78‐mediated antioxidant response and ABC transporter activity confers chemoresistance to pancreatic cancer cells P Dauer, NS Sharma, VK Gupta, A Nomura, V Dudeja, A Saluja, ... Molecular oncology 12 (9), 1498-1512, 2018 | 41 | 2018 |
| Inhibition of hypoxic response decreases stemness and reduces tumorigenic signaling due to impaired assembly of HIF1 transcription complex in pancreatic cancer O McGinn, VK Gupta, P Dauer, N Arora, N Sharma, A Nomura, V Dudeja, ... Scientific reports 7 (1), 7872, 2017 | 38 | 2017 |
| Inhibition of Sp1 prevents ER homeostasis and causes cell death by lysosomal membrane permeabilization in pancreatic cancer P Dauer, VK Gupta, O McGinn, A Nomura, NS Sharma, N Arora, B Giri, ... Scientific reports 7 (1), 1564, 2017 | 31 | 2017 |
| Stroma secreted IL6 selects for “stem-like” population and alters pancreatic tumor microenvironment by reprogramming metabolic pathways ASSB Kousik Kesh, Vanessa T. Garrido, Austin Dosch, Brittany Durden, Vineet ... Cell Death and Disease 11, 2020 | 30 | 2020 |
| “Nutrient-sensing” and self-renewal: O-GlcNAc in a new role NS Sharma, AK Saluja, S Banerjee Journal of bioenergetics and biomembranes 50, 205-211, 2018 | 28 | 2018 |
| Oncolytic Adenoviruses: Strategies for Improved Targeting and Specificity MY Praveensingh B Hajeri, Nikita S Sharma Cancers, 2020 | 22 | 2020 |
| Long non-coding RNA GAS5 acts as proliferation "brakes" in CD133+ cells responsible for tumor recurrence SB NS Sharma, P Gnamlin,B Durden, VK Gupta, K Kesh, VT Garrido,V Dudeja,A Saluja Oncogenesis 8 (68), 2019 | 22 | 2019 |
| Minnelide synergizes with conventional chemotherapy by targeting both cancer and associated stroma components in pancreatic cancer AKS Shrey Modi, Bhuwan Giri, Vineet K. Gupta, Shweta Lavania, Vrishketan ... Cancer Letters, 2022 | 9 | 2022 |
| O-GlcNAc modification of oncogenic transcription factor Sox2 promotes protein stability and regulates self-renewal in pancreatic cancer NS Sharma, VK Gupta, P Dauer, K Kesh, R Hadad, B Giri, A Chandra, ... bioRxiv, 345223, 2018 | 8 | 2018 |
| 939 Autocrine/paracrine factors in cancer associated fibroblasts drive immunosuppression through impaired myeloid cell functions N Sharma, P Govindaraju, S Bradford, Y Wang, B Flynn, CWS Lei, ... Journal for Immunotherapy of Cancer 9 (Suppl 2), A985-A985, 2021 | 1 | 2021 |
| Hypoxia-driven oncometabolite L-2HG maintains “stemness”-differentiation balance and facilitates immune suppression in pancreatic cancer VK Gupta, NS Sharma, B Durden, VT Garrido, K Kesh, D Edwards, ... bioRxiv, 2020.05. 08.084244, 2020 | 1 | 2020 |
| Targeting tumor-intrinsic metabolic node sensitizes pancreatic cancer to anti-PD1 therapy NS Sharma, VK Gupta, VT Garrido, R Hadad, BC Durden, K Kesh, B Giri, ... Cold Spring Harbor Laboratory, 2019 | 1 | 2019 |
| The ROS duality in castration-resistant prostate cancer emergence and progression C Troccoli, R Lyles, G Samaranayake, M Huynh, D Kwon, Y Ban, S Chen, ... Free Radical Biology and Medicine 128, S75, 2018 | 1 | 2018 |
Ashok SalujaVerified email at miami.edu
