| Within-Subject Comparison of [11C]-( + )-PHNO and [11C]raclopride Sensitivity to Acute Amphetamine Challenge in Healthy Humans P Shotbolt, AC Tziortzi, GE Searle, A Colasanti, J Van Der Aart, ... Journal of Cerebral Blood Flow & Metabolism 32 (1), 127-136, 2012 | 144 | 2012 |
| Testing the effects of Δ9-THC and D-cycloserine on extinction of conditioned fear in humans F Klumpers, D Denys, JL Kenemans, C Grillon, J van der Aart, JMP Baas Journal of Psychopharmacology, 2012 | 87 | 2012 |
| Prediction of repeat-dose occupancy from single-dose data: characterisation of the relationship between plasma pharmacokinetics and brain target occupancy S Abanades, J Van Der Aart, JAR Barletta, C Marzano, GE Searle, ... Journal of Cerebral Blood Flow & Metabolism 31 (3), 944-952, 2011 | 62 | 2011 |
| Radiation dose estimates for carbon-11-labelled PET tracers J van der Aart, WA Hallett, EA Rabiner, J Passchier, RA Comley Nuclear medicine and biology 39 (2), 305-314, 2012 | 49 | 2012 |
| Characterisation of the pharmacodynamic effects of the P2X7 receptor antagonist JNJ-54175446 using an oral dexamphetamine challenge model in healthy males in a randomised … K Recourt, J van der Aart, G Jacobs, M de Kam, W Drevets, L van Nueten, ... Journal of Psychopharmacology 34 (9), 1030-1042, 2020 | 45 | 2020 |
| Monoamine transporter occupancy of a novel triple reuptake inhibitor in baboons and humans using positron emission tomography RA Comley, CA Salinas, M Slifstein, M Petrone, C Marzano, I Bennacef, ... Journal of Pharmacology and Experimental Therapeutics 346 (2), 311-317, 2013 | 20 | 2013 |
| Safety, pharmacokinetics, and pharmacodynamics of Gln‐1062, a prodrug of galantamine C Bakker, J van der Aart, EP Hart, ES Klaassen, KR Bergmann, ... Alzheimer's & Dementia: Translational Research & Clinical Interventions 6 (1 …, 2020 | 18 | 2020 |
| Brain exposure of osimertinib in patients with epidermal growth factor receptor mutation non‐small cell lung cancer and brain metastases: A positron emission tomography and … S Ekman, Z Cselényi, A Varrone, A Jucaite, H Martin, M Schou, ... Clinical and Translational Science 16 (6), 955-965, 2023 | 14* | 2023 |
| First in human evaluation of [18F]PK-209, a PET ligand for the ion channel binding site of NMDA receptors J van der Aart, SSV Golla, M van der Pluijm, LA Schwarte, RC Schuit, ... EJNMMI research 8 (1), 1-12, 2018 | 12 | 2018 |
| Evaluation of the novel PET tracer [11C]HACH242 for imaging the GluN2B NMDA receptor in non-human primates J van der Aart, M Yaqub, EJM Kooijman, J Bakker, JAM Langermans, ... Molecular Imaging and Biology 21 (4), 676-685, 2019 | 11 | 2019 |
| Quantification of human brain PDE4 occupancy by GSK356278: A [11C](R)-rolipram PET study J van der Aart, C Salinas, R Dimber, S Pampols-Maso, AA Weekes, ... Journal of Cerebral Blood Flow & Metabolism 38 (11), 2033-2040, 2018 | 8 | 2018 |
| Safety and pharmacokinetics of HTL0018318, a novel M1 receptor agonist, given in combination with donepezil at steady state: a randomized trial in healthy elderly subjects C Bakker, J van der Aart, G Labots, J Liptrot, DM Cross, ES Klaassen, ... Drugs in R&D 21 (3), 295-304, 2021 | 5 | 2021 |
| In vivo occupancy of the 5-HT1A receptor by a novel pan 5-HT1(A/B/D) receptor antagonist, GSK588045, using Positron Emission Tomography RA Comley, J van der Aart, B Gulyás, M Garnier, L Iavarone, C Halldin, ... Neuropharmacology 92, 44–48, 2015 | 5 | 2015 |
| Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling S Hobor, M Al Bakir, CT Hiley, M Skrzypski, AM Frankell, B Bakker, ... Nature Communications 15 (1), 4871, 2024 | 4 | 2024 |
| Human Dosimetry of the N-Methyl-d-Aspartate Receptor Ligand 11C-GMOM J Van der Aart, T Van der Doef, P Horstman, MC Huisman, RC Schuit, ... Journal of Nuclear Medicine: Society of Nuclear Medicine 58 (8), 1330-1333, 2017 | 2 | 2017 |
| The role of clinical imaging in oncology drug development: progress and new challenges PS Murphy, P Galette, J van der Aart, RL Janiczek, N Patel, AP Brown The British Journal of Radiology 96 (1150), 20211126, 2023 | 1 | 2023 |
| Amphetamine Induced Psychomotor Improvement in Relation to Striatal Dopamine Release in Healthy Subjects J van der Aart, H van Gorsel, M de Kam, M Yaqub, AA Lammertsma, ... Journal of Cerebral Blood Flow & Metabolism 36, 735-736, 2016 | 1 | 2016 |
| TP53 loss with whole genome doubling mediates heterogeneous intra-patient therapy response in EGFR-driven lung adenocarcinoma: A TRACERx study S Hobor, MA Bakir, M Skrzypski, AM Frankell, B Bakker, TB Watkins, ... Cancer Research 82 (12_Supplement), 6217-6217, 2022 | | 2022 |
| Positron Emission Tomography of Novel Radiotracers for the Central Nervous System: Radiation Dosimetry and Translational Imaging Studies J Van der Aart Amsterdam UMC, location VUmc, 2019 | | 2019 |
| Effects of Occipital Nerve Stimulation on Cerebral Blood Flow in Patients with Medically Intractable Chronic Cluster Headache IF De Coo, J van der Aart, LA Wilbrink, PG Doesborg, H Abrabi, M Yaqub, ... CEPHALALGIA 37, 124-124, 2017 | | 2017 |
Eugenii RabinerEVP Translational Applications, InvicroVerified email at invicro.co.uk
