Richard Bourgon
Richard Bourgon
Vice President of Computational Science, Freenome
在 的电子邮件经过验证
Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm …
JE Rosenberg, J Hoffman-Censits, T Powles, MS Van Der Heijden, ...
The Lancet 387 (10031), 1909-1920, 2016
TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
S Mariathasan, SJ Turley, D Nickles, A Castiglioni, K Yuen, Y Wang, ...
Nature 554 (7693), 544-548, 2018
Atezolizumab as first-line treatment in cisplatin-ineligible patients with locally advanced and metastatic urothelial carcinoma: a single-arm, multicentre, phase 2 trial
AV Balar, MD Galsky, JE Rosenberg, T Powles, DP Petrylak, J Bellmunt, ...
The Lancet 389 (10064), 67-76, 2017
Diverse somatic mutation patterns and pathway alterations in human cancers
Z Kan, BS Jaiswal, J Stinson, V Janakiraman, D Bhatt, HM Stern, P Yue, ...
Nature 466 (7308), 869-873, 2010
Recurrent R-spondin fusions in colon cancer
S Seshagiri, EW Stawiski, S Durinck, Z Modrusan, EE Storm, CB Conboy, ...
Nature 488 (7413), 660-664, 2012
Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
CM Rudin, S Durinck, EW Stawiski, JT Poirier, Z Modrusan, DS Shames, ...
Nature genetics 44 (10), 1111-1116, 2012
Independent filtering increases detection power for high-throughput experiments
R Bourgon, R Gentleman, W Huber
Proceedings of the National Academy of Sciences 107 (21), 9546-9551, 2010
Genome-wide analysis of Polycomb targets in Drosophila melanogaster
YB Schwartz, TG Kahn, DA Nix, XY Li, R Bourgon, M Biggin, V Pirrotta
Nature genetics 38 (6), 700-705, 2006
High-resolution mapping of meiotic crossovers and non-crossovers in yeast
E Mancera, R Bourgon, A Brozzi, W Huber, LM Steinmetz
Nature 454 (7203), 479-485, 2008
Correction: Transcription Factors Bind Thousands of Active and Inactive Regions in the Drosophila Blastoderm
X Li, S MacArthur, R Bourgon, D Nix, DA Pollard, VN Iyer, A Hechmer, ...
PLoS Biology 6 (7), 2008
Transcription Factors Bind Thousands of Active and Inactive Regions in the Drosophila Blastoderm
X Li, S MacArthur, R Bourgon, D Nix, DA Pollard, VN Iyer, A Hechmer, ...
PLoS biology 6 (2), e27, 2008
A comprehensive transcriptional portrait of human cancer cell lines
C Klijn, S Durinck, EW Stawiski, PM Haverty, Z Jiang, H Liu, J Degenhardt, ...
Nature biotechnology 33 (3), 306-312, 2015
Genomic analysis of smoothened inhibitor resistance in basal cell carcinoma
HJ Sharpe, G Pau, GJ Dijkgraaf, N Basset-Seguin, Z Modrusan, ...
Cancer cell 27 (3), 327-341, 2015
TRPS1 targeting by miR-221/222 promotes the epithelial-to-mesenchymal transition in breast cancer
S Stinson, MR Lackner, AT Adai, N Yu, HJ Kim, C O’Brien, J Spoerke, ...
Science signaling 4 (177), ra41-ra41, 2011
Patients with proneural glioblastoma may derive overall survival benefit from the addition of bevacizumab to first-line radiotherapy and temozolomide: retrospective analysis of …
T Sandmann, R Bourgon, J Garcia, C Li, T Cloughesy, OL Chinot, W Wick, ...
Journal of clinical oncology 33 (25), 2735, 2015
Reproducible pharmacogenomic profiling of cancer cell line panels
PM Haverty, E Lin, J Tan, Y Yu, B Lam, S Lianoglou, RM Neve, S Martin, ...
Nature 533 (7603), 333-337, 2016
Alternative epigenetic chromatin states of polycomb target genes
YB Schwartz, TG Kahn, P Stenberg, K Ohno, R Bourgon, V Pirrotta
PLoS genetics 6 (1), e1000805, 2010
Peripheral T cell expansion predicts tumour infiltration and clinical response
TD Wu, S Madireddi, PE de Almeida, R Banchereau, YJJ Chen, AS Chitre, ...
Nature 579 (7798), 274-278, 2020
A resource for cell line authentication, annotation and quality control
M Yu, SK Selvaraj, MMY Liang-Chu, S Aghajani, M Busse, J Yuan, G Lee, ...
Nature 520 (7547), 307-311, 2015
Single-cell RNA sequencing reveals stromal evolution into LRRC15+ myofibroblasts as a determinant of patient response to cancer immunotherapy
CX Dominguez, S Müller, S Keerthivasan, H Koeppen, J Hung, S Gierke, ...
Cancer discovery 10 (2), 232-253, 2020
文章 1–20