| Identification of a primary target of thalidomide teratogenicity T Ito, H Ando, T Suzuki, T Ogura, K Hotta, Y Imamura, Y Yamaguchi, ... science 327 (5971), 1345-1350, 2010 | 2096 | 2010 |
| NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation Y Yamaguchi, T Takagi, T Wada, K Yano, A Furuya, S Sugimoto, ... Cell 97 (1), 41-51, 1999 | 1021 | 1999 |
| DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs T Wada, T Takagi, Y Yamaguchi, A Ferdous, T Imai, S Hirose, S Sugimoto, ... Genes & development 12 (3), 343-356, 1998 | 948 | 1998 |
| Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide AEA Lopez-Girona, D Mendy, T Ito, K Miller, AK Gandhi, J Kang, ... Leukemia 26 (11), 2326-2335, 2012 | 867 | 2012 |
| An SV40-immortalized human corneal epithelial cell line and its characterization. K Araki-Sasaki, Y Ohashi, T Sasabe, K Hayashi, H Watanabe, Y Tano, ... Investigative ophthalmology & visual science 36 (3), 614-621, 1995 | 860 | 1995 |
| Redox regulation of NF-κB activation: distinct redox regulation between the cytoplasm and the nucleus Y Kabe, K Ando, S Hirao, M Yoshida, H Handa Antioxidants & redox signaling 7 (3-4), 395-403, 2005 | 684 | 2005 |
| Immunomodulatory agents lenalidomide and pomalidomide co‐stimulate T cells by inducing degradation of T cell repressors I karos and A iolos via modulation of the E 3 ubiquitin … AK Gandhi, J Kang, CG Havens, T Conklin, Y Ning, L Wu, T Ito, H Ando, ... British journal of haematology 164 (6), 811-821, 2014 | 641 | 2014 |
| A common trans-acting factor, Ad4-binding protein, to the promoters of steroidogenic P-450s. KI Morohashi, SI Honda, Y Inomata, H Handa, T Omura Journal of Biological Chemistry 267 (25), 17913-17919, 1992 | 615 | 1992 |
| Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II inSaccharomyces cerevisiae GA Hartzog, T Wada, H Handa, F Winston Genes & development 12 (3), 357-369, 1998 | 585 | 1998 |
| Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs PP Chamberlain, A Lopez-Girona, K Miller, G Carmel, B Pagarigan, ... Nature structural & molecular biology 21 (9), 803-809, 2014 | 511 | 2014 |
| A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase ME Matyskiela, G Lu, T Ito, B Pagarigan, CC Lu, K Miller, W Fang, ... Nature 535 (7611), 252-257, 2016 | 505 | 2016 |
| P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation T Yamada, Y Yamaguchi, N Inukai, S Okamoto, T Mura, H Handa Molecular cell 21 (2), 227-237, 2006 | 479 | 2006 |
| Evidence that P‐TEFb alleviates the negative effect of DSIF on RNA polymerase II‐dependent transcription in vitro T Wada, T Takagi, Y Yamaguchi, D Watanabe, H Handa The EMBO journal, 1998 | 453 | 1998 |
| NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila CH Wu, Y Yamaguchi, LR Benjamin, M Horvat-Gordon, J Washinsky, ... Genes & development 17 (11), 1402-1414, 2003 | 388 | 2003 |
| MafA is a glucose-regulated and pancreatic β-cell-specific transcriptional activator for the insulin gene K Kataoka, S Han, S Shioda, M Hirai, M Nishizawa, H Handa Journal of Biological Chemistry 277 (51), 49903-49910, 2002 | 372 | 2002 |
| Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex T Narita, Y Yamaguchi, K Yano, S Sugimoto, S Chanarat, T Wada, D Kim, ... Molecular and cellular biology 23 (6), 1863-1873, 2003 | 322 | 2003 |
| Mutations of the PAX6 gene detected in patients with a variety of optic-nerve malformations N Azuma, Y Yamaguchi, H Handa, K Tadokoro, A Asaka, E Kawase, ... The American Journal of Human Genetics 72 (6), 1565-1570, 2003 | 301 | 2003 |
| High-performance affinity beads for identifying drug receptors N Shimizu, K Sugimoto, J Tang, T Nishi, I Sato, M Hiramoto, S Aizawa, ... Nature biotechnology 18 (8), 877-881, 2000 | 299 | 2000 |
| Spatial redox regulation of a critical cysteine residue of NF-κB in vivo T Nishi, N Shimizu, M Hiramoto, I Sato, Y Yamaguchi, M Hasegawa, ... Journal of Biological Chemistry 277 (46), 44548-44556, 2002 | 275 | 2002 |
| Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA Y Yamaguchi, N Inukai, T Narita, T Wada, H Handa Molecular and cellular biology 22 (9), 2918-2927, 2002 | 275 | 2002 |
