| Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients A Bonehill, AMT Van Nuffel, J Corthals, S Tuyaerts, C Heirman, ... Clinical Cancer Research 15 (10), 3366-3375, 2009 | 271 | 2009 |
| Enhancing the T-cell stimulatory capacity of human dendritic cells by co-electroporation with CD40L, CD70 and constitutively active TLR4 encoding mRNA A Bonehill, S Tuyaerts, AMT Van Nuffel, C Heirman, TJ Bos, K Fostier, ... Molecular Therapy 16 (6), 1170-1180, 2008 | 215 | 2008 |
| A phase IB study on intravenous synthetic mRNA electroporated dendritic cell immunotherapy in pretreated advanced melanoma patients S Wilgenhof, AMT Van Nuffel, D Benteyn, J Corthals, C Aerts, C Heirman, ... Annals of Oncology 24 (10), 2686-2693, 2013 | 213 | 2013 |
| Therapeutic vaccination with an autologous mRNA electroporated dendritic cell vaccine in patients with advanced melanoma S Wilgenhof, AMT Van Nuffel, J Corthals, C Heirman, S Tuyaerts, ... Journal of immunotherapy 34 (5), 448-456, 2011 | 158 | 2011 |
| Dendritic cells loaded with mRNA encoding full-length tumor antigens prime CD4+ and CD8+ T cells in melanoma patients AMT Van Nuffel, D Benteyn, S Wilgenhof, L Pierret, J Corthals, C Heirman, ... Molecular Therapy 20 (5), 1063-1074, 2012 | 109 | 2012 |
| ReDO_DB: the repurposing drugs in oncology database P Pantziarka, C Verbaanderd, V Sukhatme, IR Capistrano, S Crispino, ... ecancermedicalscience 12, 2018 | 103 | 2018 |
| Repurposing Drugs in Oncology (ReDO)—clarithromycin as an anti-cancer agent AMT Van Nuffel, V Sukhatme, P Pantziarka, L Meheus, VP Sukhatme, ... ecancermedicalscience 9, 2015 | 81 | 2015 |
| Long-term clinical outcome of melanoma patients treated with messenger RNA-electroporated dendritic cell therapy following complete resection of metastases S Wilgenhof, J Corthals, AMT Van Nuffel, D Benteyn, C Heirman, ... Cancer Immunology, Immunotherapy 64, 381-388, 2015 | 80 | 2015 |
| Intravenous and intradermal TriMix-dendritic cell therapy results in a broad T-cell response and durable tumor response in a chemorefractory stage IV-M1c melanoma patient AMT Van Nuffel, D Benteyn, S Wilgenhof, J Corthals, C Heirman, B Neyns, ... Cancer Immunology, Immunotherapy 61, 1033-1043, 2012 | 76 | 2012 |
| Modulation of regulatory T cell function by monocyte-derived dendritic cells matured through electroporation with mRNA encoding CD40 ligand, constitutively active TLR4, and CD70 JJ Pen, B De Keersmaecker, SK Maenhout, AMT Van Nuffel, C Heirman, ... The Journal of Immunology 191 (4), 1976-1983, 2013 | 52 | 2013 |
| PRIMMO study protocol: a phase II study combining PD-1 blockade, radiation and immunomodulation to tackle cervical and uterine cancer S Tuyaerts, AMT Van Nuffel, E Naert, PA Van Dam, P Vuylsteke, ... BMC cancer 19, 1-10, 2019 | 47 | 2019 |
| Immunotherapy of cancer with dendritic cells loaded with tumor antigens and activated through mRNA electroporation AMT Van Nuffel, J Corthals, B Neyns, C Heirman, K Thielemans, ... Rna Therapeutics: Function, Design, and Delivery, 403-450, 2010 | 46 | 2010 |
| Design of an optimized Wilms’ tumor 1 (WT1) mRNA construct for enhanced WT1 expression and improved immunogenicity in vitro and in vivo D Benteyn, S Anguille, S Van Lint, C Heirman, AMT Van Nuffel, J Corthals, ... Molecular Therapy-Nucleic Acids 2, 2013 | 44 | 2013 |
| A phase 2 study to assess the immunomodulatory capacity of a lecithin-based delivery system of curcumin in endometrial cancer S Tuyaerts, K Rombauts, T Everaert, AMT Van Nuffel, F Amant Frontiers in nutrition 5, 138, 2019 | 39 | 2019 |
| Overcoming HLA restriction in clinical trials: immune monitoring of mRNA-loaded DC therapy AMT Van Nuffel, S Wilgenhof, K Thielemans, A Bonehill Oncoimmunology 1 (8), 1392-1394, 2012 | 36 | 2012 |
| Characterization of CD8+ T-cell responses in the peripheral blood and skin injection sites of melanoma patients treated with mRNA electroporated autologous dendritic cells … D Benteyn, AMT Van Nuffel, S Wilgenhof, J Corthals, C Heirman, B Neyns, ... BioMed research international 2013, 2013 | 35 | 2013 |
| Epitope and HLA-type independent monitoring of antigen-specific T-cells after treatment with dendritic cells presenting full-length tumor antigens AMT Van Nuffel, S Tuyaerts, D Benteyn, S Wilgenhof, J Corthals, ... Journal of immunological methods 377 (1-2), 23-36, 2012 | 29 | 2012 |
| Repurposing infectious diseases vaccines against cancer L Vandeborne, P Pantziarka, AMT Van Nuffel, G Bouche Frontiers in oncology 11, 688755, 2021 | 26 | 2021 |
| Pembrolizumab, radiotherapy, and an immunomodulatory five-drug cocktail in pretreated patients with persistent, recurrent, or metastatic cervical or endometrial carcinoma … EA De Jaeghere, S Tuyaerts, AMT Van Nuffel, A Belmans, K Bogaerts, ... Cancer Immunology, Immunotherapy 72 (2), 475-491, 2023 | 24 | 2023 |
| Single-step antigen loading and maturation of dendritic cells through mRNA electroporation of a tumor-associated antigen and a TriMix of costimulatory molecules D Benteyn, AMT Van Nuffel, S Wilgenhof, A Bonehill Cancer Vaccines: Methods and Protocols, 3-15, 2014 | 16 | 2014 |
