Mycophenolic acid and its metabolites in kidney transplant recipients: a semimechanistic enterohepatic circulation model to improve estimating exposure M Okour, PA Jacobson, MA Ahmed, AK Israni, RC Brundage The Journal of Clinical Pharmacology 58 (5), 628-639, 2018 | 33 | 2018 |
Modeling enterohepatic circulation M Okour, RC Brundage Current Pharmacology Reports 3, 301-313, 2017 | 21 | 2017 |
Hydroxychloroquine and azithromycin as potential treatments for COVID-19; clinical status impacts the outcome M Okour, M Al-Kofahi, D Austin Journal of pharmacokinetics and pharmacodynamics 47, 187-188, 2020 | 20 | 2020 |
Orphan drug development: the increasing role of clinical pharmacology MA Ahmed, M Okour, R Brundage, RV Kartha Journal of Pharmacokinetics and Pharmacodynamics 46, 395-409, 2019 | 17 | 2019 |
A randomized study of safety and efficacy of two doses of ambrisentan to treat pulmonary arterial hypertension in pediatric patients aged 8 years up to 18 years D Ivy, M Beghetti, E Juaneda-Simian, D Miller, MA Lukas, C Ioannou, ... The Journal of Pediatrics: X 5, 100055, 2020 | 14 | 2020 |
Drug combination modeling: methods and applications in drug development RA Pearson, SG Wicha, M Okour The Journal of Clinical Pharmacology 63 (2), 151-165, 2023 | 13 | 2023 |
A human microdose study of the antimalarial drug GSK3191607 in healthy volunteers M Okour, G Derimanov, R Barnett, E Fernandez, S Ferrer, S Gresham, ... British Journal of Clinical Pharmacology 84 (3), 482-489, 2018 | 10 | 2018 |
A population analysis of the DGAT1 inhibitor GSK3008356 and its effect on endogenous and meal‐induced triglyceride turnover in healthy subjects M Okour, RA Brigandi, D Tenero Fundamental & Clinical Pharmacology 33 (5), 567-580, 2019 | 7 | 2019 |
Comparative Evaluation of Median Versus Youden Index Dichotomization Methods: Exposure–Response Analysis of Mycophenolic Acid and Acyl-Glucuronide Metabolite M Okour, PA Jacobson, A Israni, RC Brundage European journal of drug metabolism and pharmacokinetics 44, 629-638, 2019 | 6 | 2019 |
Evaluation of Potential Therapeutic Options for COVID‐19. D Austin, M Okour Journal of clinical pharmacology 60 (8), 2020 | 5 | 2020 |
Population pharmacokinetic analysis of fluticasone furoate/umeclidinium bromide/vilanterol in patients with chronic obstructive pulmonary disease R Mehta, C Farrell, S Hayes, R Birk, M Okour, DA Lipson Clinical Pharmacokinetics 59, 67-79, 2020 | 5 | 2020 |
Rapid antibody responses to Epstein-Barr virus correlate with reduced severity of primary infection JM Geris, AL Stancari, MR Meirhaeghe, S Gautam, C Cayatte, ... Journal of Clinical Virology 155, 105267, 2022 | 4 | 2022 |
A gallbladder-based enterohepatic circulation model for pharmacokinetic studies M Okour, RC Brundage European Journal of Drug Metabolism and Pharmacokinetics 44, 493-504, 2019 | 4 | 2019 |
DosePredict: A shiny application for generalized pharmacokinetics‐based dose predictions M Okour The Journal of Clinical Pharmacology 60 (11), 1502-1508, 2020 | 3 | 2020 |
Population pharmacokinetic/pharmacodynamic analysis of intravenous zanamivir in healthy adults and hospitalized adult and pediatric subjects with influenza P Zuo, J Collins, M Okour, A Barth, D Shortino, P Yates, G Roberts, ... Clinical and Translational Science 13 (1), 157-168, 2020 | 3 | 2020 |
First‐in‐Human Pharmacokinetics and Safety Study of GSK3008356, a Selective DGAT1 Inhibitor, in Healthy Volunteers M Okour, A Gress, X Zhu, D Rieman, JD Lickliter, RA Brigandi Clinical Pharmacology in Drug Development 8 (8), 1088-1099, 2019 | 3 | 2019 |
A phase I study to show the relative bioavailability and bioequivalence of fixed-dose combinations of ambrisentan and tadalafil in healthy subjects M Okour, A Puri, G Chen, K Port, A Berni, S Khindri, I Schneider, D Tenero Clinical Therapeutics 41 (6), 1110-1127, 2019 | 2 | 2019 |
The Pharmacokinetics of Enterohepatic Circulation MF Okour University of Minnesota, 2015 | 2 | 2015 |
Pediatric Population Pharmacokinetic Modeling and Exposure–Response Analysis of Ambrisentan in Pulmonary Arterial Hypertension and Comparison With Adult Data M Okour, MM Thapar, C Farrell, MA Lukas, M Beghetti, M Beerahee The Journal of Clinical Pharmacology 63 (5), 593-603, 2023 | 1 | 2023 |
Safety and Pharmacokinetics of the Anti-SARS-CoV-2 Monoclonal Antibody, Sotrovimab, Administered by Intravenous Injection in Japanese and Caucasian Healthy Volunteers A Okamasa, M Okour, D Austin, Y Shida, JE Sager, E Alexander, ... Kansenshogaku Zasshi, 39-45, 2022 | 1 | 2022 |