Factor IX expression in skeletal muscle of a severe hemophilia B patient 10 years after AAV-mediated gene transfer G Buchlis, GM Podsakoff, A Radu, SM Hawk, AW Flake, F Mingozzi, ... Blood, The Journal of the American Society of Hematology 119 (13), 3038-3041, 2012 | 245 | 2012 |
CCL2 blockade augments cancer immunotherapy ZG Fridlender, G Buchlis, V Kapoor, G Cheng, J Sun, S Singhal, ... Cancer research 70 (1), 109-118, 2010 | 198 | 2010 |
Monocyte Chemoattractant Protein–1 Blockade Inhibits Lung Cancer Tumor Growth by Altering Macrophage Phenotype and Activating CD8+ Cells ZG Fridlender, V Kapoor, G Buchlis, G Cheng, J Sun, LCS Wang, ... American journal of respiratory cell and molecular biology 44 (2), 230-237, 2011 | 160 | 2011 |
Peripheral transvenular delivery of adeno-associated viral vectors to skeletal muscle as a novel therapy for hemophilia B VR Arruda, HH Stedman, V Haurigot, G Buchlis, S Baila, P Favaro, ... Blood, The Journal of the American Society of Hematology 115 (23), 4678-4688, 2010 | 139 | 2010 |
Systemic blockade of transforming growth factor-β signaling augments the efficacy of immunogene therapy S Kim, G Buchlis, ZG Fridlender, J Sun, V Kapoor, G Cheng, A Haas, ... Cancer research 68 (24), 10247-10256, 2008 | 112 | 2008 |
Safety of AAV factor IX peripheral transvenular gene delivery to muscle in hemophilia B dogs V Haurigot, F Mingozzi, G Buchlis, DJ Hui, Y Chen, E Basner-Tschakarjan, ... Molecular Therapy 18 (7), 1318-1329, 2010 | 91 | 2010 |
Cardiac gene transfer of short hairpin RNA directed against phospholamban effectively knocks down gene expression but causes cellular toxicity in canines LT Bish, MM Sleeper, C Reynolds, J Gazzara, E Withnall, GE Singletary, ... Human gene therapy 22 (8), 969-977, 2011 | 56 | 2011 |
Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes DJ Hui, E Basner-Tschakarjan, Y Chen, RJ Davidson, G Buchlis, ... Molecular Therapy 21 (9), 1727-1737, 2013 | 47 | 2013 |
Evaluation of the humoral response to adeno-associated virus-based gene therapy modalities using total antibody assays B Gorovits, M Azadeh, G Buchlis, T Harrison, M Havert, V Jawa, B Long, ... The AAPS journal 23, 1-17, 2021 | 38 | 2021 |
Crucial roles of TNFAIP8 protein in regulating apoptosis and Listeria infection TP Porturas, H Sun, G Buchlis, Y Lou, X Liang, T Cathopoulis, ... The Journal of Immunology 194 (12), 5743-5750, 2015 | 37 | 2015 |
Enhanced T cell function in a mouse model of human glycosylation G Buchlis, P Odorizzi, PC Soto, OMT Pearce, DJ Hui, MS Jordan, A Varki, ... The Journal of Immunology 191 (1), 228-237, 2013 | 28 | 2013 |
Adeno-associated Virus-Mediated CRISPR-Cas9 Treatment of Ocular Disease G Buchlis, X Anguela, KA High US Patent App. 15/143,272, 2016 | 14 | 2016 |
Evaluation of cellular immune response to adeno-associated virus-based gene therapy B Gorovits, M Azadeh, G Buchlis, M Fiscella, T Harrison, M Havert, ... The AAPS journal 25 (3), 47, 2023 | 11 | 2023 |
Potency assay for AAV vector encoding retinal pigment epithelial 65 protein LB Couto, G Buchlis, R Farjo, K High Investigative Ophthalmology & Visual Science 57 (12), 759-759, 2016 | 8 | 2016 |
Intrinsically Hyperactive and Hyperproliferative CD8+ T Cells In Cmah-/-Mice as a Model of Human Gene Transfer Responses. G Buchlis, F Mingozzi, PC Soto, O Pearce, DJ Hui, AP Varki, KA High Blood 116 (21), 3773, 2010 | 1 | 2010 |
Identification of Transgene-Specific CD4+ FOXP3+ T Cells Secreting High Levels of IL-10 Following Intravascular AAV-cF. IX Gene Transfer to Muscle in Hemophilia B Dogs GJ Buchlis, DJ Hui, J Finn, GC Pien, S Edmonson, A Dillow, TC Nichols, ... Molecular Therapy 17, S245-S245, 2009 | 1 | 2009 |
Detection of Humoral Response to Transgene Protein and Gene Editing Reagents G Buchlis, B Gorovits Drug Development for Gene Therapy: Translational Biomarkers, Bioanalysis …, 2024 | | 2024 |
High-dose systemic adeno-associated virus vector administration causes liver and sinusoidal endothelial cell injury J Hordeaux, RJ Lamontagne, C Song, G Buchlis, C Dyer, EL Buza, ... Molecular Therapy, 2024 | | 2024 |
Adeno-Associated Virus-Mediated CRISPR-Cas9 Treatment of Ocular Disease G Buchlis, X Anguela, KA High US Patent App. 17/816,367, 2022 | | 2022 |
High-dose systemic adeno-associated virus causes acute hepatocellular and liver sinusoidal endothelial cell injury in macaques J Hordeaux, CJ Song, RJ Lamontagne, C Dyer, EL Buza, G Buchlis, ... HUMAN GENE THERAPY 33 (23-24), A160-A160, 2022 | | 2022 |