Pharmacological, mechanistic, and pharmacokinetic assessment of novel melatonin-tamoxifen drug conjugates as breast cancer drugs M Hasan, MA Marzouk, S Adhikari, TD Wright, BP Miller, MD Matossian, ... Molecular Pharmacology 96 (2), 272-296, 2019 | 39 | 2019 |
Pharmacological inhibition of the MEK5/ERK5 and PI3K/Akt signaling pathways synergistically reduces viability in triple‐negative breast cancer TD Wright, C Raybuck, A Bhatt, D Monlish, S Chakrabarty, K Wendekier, ... Journal of cellular biochemistry 121 (2), 1156-1168, 2020 | 30 | 2020 |
Novel diphenylamine analogs induce mesenchymal to epithelial transition in triple negative breast cancer AB Bhatt, M Gupta, VT Hoang, S Chakrabarty, TD Wright, S Elliot, ... Frontiers in oncology 9, 672, 2019 | 17 | 2019 |
Structure activity relationships of anthranilic acid-based compounds on cellular and in vivo mitogen activated protein kinase-5 signaling pathways S Chakrabarty, DA Monlish, M Gupta, TD Wright, VT Hoang, M Fedak, ... Bioorganic & medicinal chemistry letters 28 (13), 2294-2301, 2018 | 15 | 2018 |
Morphine exposure reduces nicotine-induced upregulation of nicotinic receptors and decreases volitional nicotine intake in a mouse model AJ Avelar, SY Cooper, TD Wright, SK Wright, MR Richardson, ... Nicotine and Tobacco Research 24 (8), 1161-1168, 2022 | 10 | 2022 |
Dual inhibition of MEK1/2 and MEK5 suppresses the EMT/migration axis in triple‐negative breast cancer through FRA‐1 regulation VT Hoang, MD Matossian, J La, K Hoang, DA Ucar, S Elliott, HE Burks, ... Journal of cellular biochemistry 122 (8), 835-850, 2021 | 9 | 2021 |
Multi-institutional outcomes and associations after excision and primary anastomosis for radiotherapy-associated bulbomembranous urethral stenoses following prostate cancer … BB Voelzke, LS Leddy, JB Myers, BN Breyer, NF Alsikafi, JA Broghammer, ... Urology 152, 117-122, 2021 | 9 | 2021 |
Diverse and converging roles of ERK1/2 and ERK5 pathways on mesenchymal to epithelial transition in breast cancer AB Bhatt, TD Wright, V Barnes, S Chakrabarty, MD Matossian, E Lexner, ... Translational oncology 14 (6), 101046, 2021 | 5 | 2021 |
Melatonin-tamoxifen hybrid ligands and their effects on breast cancer M Hasan, MA Marzouk, S Adhikari, T Wright, B Miller, B Peckich, ... Cancer Research 78 (13_Supplement), 3915-3915, 2018 | 2 | 2018 |
Abstract P2-03-04: A novel druggable target upstream of Notch: MEK5/ERK5 signaling regulates Jagged-1 and Notch1 expression in triple negative breast cancer stem cells DA Ucar, MD Matossian, VT Hoang-Barnes, FM Hossain, M Gupta, ... Cancer Research 79 (4_Supplement), P2-03-04-P2-03-04, 2019 | 1 | 2019 |
Dual Inhibition of the PI3K/Akt and MEK5/ERK5 Pathways for the Treatment of Breast Cancer TD Wright Duquesne University, 2019 | 1 | 2019 |
4, 6-Disubstituted quinazoline derivatives as inhibitors of the MEK5/ERK5 pathway S Patel, A Motta, P Flaherty, A Bhatt, T Wright, J Cavanaugh ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | 1 | 2018 |
An Expert System for Selection of Axial Fans MA Wright, T Wright, DG Jackson Jr Computers in Engineering: Proceedings of the... ASME International Computers …, 1988 | 1 | 1988 |
Targeting the ERK5 and ERK1/2 pathways simultaneously induces mesenchymal to epithelial transition in TNBC A Bhatt, T Wright, V Barnes, S Chakrabarty, P Flaherty, M Burow, ... Cancer Research 80 (16_Supplement), 5042-5042, 2020 | | 2020 |
Abstract B078: Inhibition of the MAPK pathways enhances the sensitivity of triple negative breast cancer cells to chemotherapeutic drugs AB Bhatt, TD Wright, S Patel, S Chakrabarty, V Barnes, M Burow, ... Molecular Cancer Therapeutics 18 (12_Supplement), B078-B078, 2019 | | 2019 |
4, 6-Disubustituted quinazolines as MEK5 inhibitors P Flaherty, S Patel, A Bhatt, T Wright, J Cavanaugh, M Burow ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
Melatonin-tamoxifen drug conjugates: Mechanism against breast cancer cells, and pharmacokinetic assessment in female mice M Hasan, TD Wright, S Adhikari, MA Marzouk, A Pericoloso, K Murgas, ... Cancer Research 79 (13_Supplement), 3893-3893, 2019 | | 2019 |
Novel diphenylamine analogs induce mesenchymal to epithelial transition and enhance the sensitivity of breast cancer cells to conventional chemotherapeutic agents AB Bhatt, TD Wright, K Anna, M Gupta, S Chakrabarty, V Hoang, M Burow, ... Cancer Research 79 (13_Supplement), 1879-1879, 2019 | | 2019 |
Abstract P5-08-07: Study of diphenylamine analogs as inducers of mesenchymal to epithelial transition in breast cancer AB Bhatt, TD Wright, K Anna, M Gupta, S Chakrabarty, PT Flaherty, ... Cancer Research 79 (4_Supplement), P5-08-07-P5-08-07, 2019 | | 2019 |
A novel druggable target upstream of Notch: MEK5/ERK5 signaling regulates Jagged-1 and Notch1 expression in triple negative breast cancer stem cells DA Ucar, MD Matossian, VT Hoang-Barnes, FM Hossain, M Gupta, ... CANCER RESEARCH 79 (4), 2019 | | 2019 |