| Comparison of the usefulness of the MTT, ATP, and calcein assays to predict the potency of cytotoxic agents in various human cancer cell lines H Mueller, MU Kassack, M Wiese SLAS Discovery 9 (6), 506-515, 2004 | 318 | 2004 |
| Common variants in P2RY11 are associated with narcolepsy BR Kornum, M Kawashima, J Faraco, L Lin, TJ Rico, S Hesselson, ... Nature genetics 43 (1), 66-71, 2011 | 258 | 2011 |
| Structure–Activity Studies on Suramin Analogues as Inhibitors of NAD+‐Dependent Histone Deacetylases (Sirtuins) J Trapp, R Meier, D Hongwiset, MU Kassack, W Sippl, M Jung ChemMedChem: Chemistry Enabling Drug Discovery 2 (10), 1419-1431, 2007 | 236 | 2007 |
| Histone deacetylase (HDAC) inhibitors with a novel connecting unit linker region reveal a selectivity profile for HDAC4 and HDAC5 with improved activity against chemoresistant … L Marek, A Hamacher, FK Hansen, K Kuna, H Gohlke, MU Kassack, ... Journal of medicinal chemistry 56 (2), 427-436, 2013 | 234 | 2013 |
| Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells N Eckstein, K Servan, B Hildebrandt, A Pölitz, G Jonquières, ... Cancer research 69 (7), 2996-3003, 2009 | 211 | 2009 |
| Relevance of drug uptake and efflux for cisplatin sensitivity of tumor cells J Zisowsky, S Koegel, S Leyers, K Devarakonda, MU Kassack, M Osmak, ... Biochemical pharmacology 73 (2), 298-307, 2007 | 178 | 2007 |
| Extracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytes I Moreschi, S Bruzzone, RA Nicholas, F Fruscione, L Sturla, F Benvenuto, ... Journal of Biological Chemistry 281 (42), 31419-31429, 2006 | 167 | 2006 |
| Discovery of Potent and Selective Agonists for the Free Fatty Acid Receptor 1 (FFA1/GPR40), a Potential Target for the Treatment of Type II Diabetes E Christiansen, C Urban, N Merten, K Liebscher, KK Karlsen, A Hamacher, ... Journal of medicinal chemistry 51 (22), 7061-7064, 2008 | 150 | 2008 |
| Purinergic receptors influence the differentiation of human mesenchymal stem cells N Zippel, CA Limbach, N Ratajski, C Urban, C Luparello, A Pansky, ... Stem cells and development 21 (6), 884-900, 2012 | 144 | 2012 |
| Inhibition of neutrophil apoptosis by ATP is mediated by the P2Y11 receptor KR Vaughan, L Stokes, LR Prince, HM Marriott, S Meis, MU Kassack, ... The Journal of Immunology 179 (12), 8544-8553, 2007 | 143 | 2007 |
| Structure-activity relationships of suramin and pyridoxal-5'-phosphate derivatives as P2 receptor antagonists G Lambrecht, K Braun, S Damer, M Ganso, C Hildebrandt, H Ullmann, ... Current pharmaceutical design 8 (26), 2371-2399, 2002 | 138 | 2002 |
| Hetero-oligomerization of the P2Y11 receptor with the P2Y1 receptor controls the internalization and ligand selectivity of the P2Y11 receptor D Ecke, T Hanck, ME Tulapurkar, R Schäfer, M Kassack, R Stricker, ... Biochemical Journal 409 (1), 107-116, 2008 | 135 | 2008 |
| Sila-haloperidol: A Silicon Analogue of the Dopamine (D2) Receptor Antagonist Haloperidol R Tacke, T Heinrich, R Bertermann, C Burschka, A Hamacher, ... Organometallics 23 (19), 4468-4477, 2004 | 123 | 2004 |
| Epidermal growth factor receptor pathway analysis identifies amphiregulin as a key factor for cisplatin resistance of human breast cancer cells N Eckstein, K Servan, L Girard, D Cai, G Von Jonquieres, U Jaehde, ... Journal of Biological Chemistry 283 (2), 739-750, 2008 | 117 | 2008 |
| Synthesis and Structure−Activity Relationships of Suramin-Derived P2Y11 Receptor Antagonists with Nanomolar Potency H Ullmann, S Meis, D Hongwiset, C Marzian, M Wiese, P Nickel, ... Journal of medicinal chemistry 48 (22), 7040-7048, 2005 | 114 | 2005 |
| Structure–activity relationships of analogues of NF449 confirm NF449 as the most potent and selective known P2X1 receptor antagonist MU Kassack, K Braun, M Ganso, H Ullmann, P Nickel, B Böing, G Müller, ... European journal of medicinal chemistry 39 (4), 345-357, 2004 | 114 | 2004 |
| Functional screening of G protein–coupled receptors by measuring intracellular calcium with a fluorescence microplate reader MU Kassack, B Höfgen, J Lehmann, N Eckstein, JM Quillan, W Sadee SLAS Discovery 7 (3), 233-246, 2002 | 111 | 2002 |
| Pro-apoptotic and immunostimulatory tetrahydroxanthone dimers from the endophytic fungus Phomopsis longicolla D Rönsberg, A Debbab, A Mándi, V Vasylyeva, P Böhler, B Stork, ... The Journal of organic chemistry 78 (24), 12409-12425, 2013 | 110 | 2013 |
| Three diketopiperazine alkaloids with spirocyclic skeletons and one bisthiodiketopiperazine derivative from the mangrove-derived endophytic fungus Penicillium brocae MA-231 LH Meng, CY Wang, A Mándi, XM Li, XY Hu, MU Kassack, T Kurtán, ... Organic letters 18 (20), 5304-5307, 2016 | 107 | 2016 |
| NF546 [4, 4′-(carbonylbis (imino-3, 1-phenylene-carbonylimino-3, 1-(4-methyl-phenylene)-carbonylimino))-bis (1, 3-xylene-α, α′-diphosphonic acid) tetrasodium salt] is a non … S Meis, A Hamacher, D Hongwiset, C Marzian, M Wiese, N Eckstein, ... Journal of Pharmacology and Experimental Therapeutics 332 (1), 238-247, 2010 | 105 | 2010 |
