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Jaya Bhatnagar
Jaya Bhatnagar
Syngene International
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Year
Reconstruction of the chemotaxis receptor–kinase assembly
SY Park, PP Borbat, G Gonzalez-Bonet, J Bhatnagar, AM Pollard, ...
Nature structural & molecular biology 13 (5), 400-407, 2006
3132006
Structure of the ternary complex formed by a chemotaxis receptor signaling domain, the CheA histidine kinase, and the coupling protein CheW as determined by pulsed dipolar ESR …
J Bhatnagar, PP Borbat, AM Pollard, AM Bilwes, JH Freed, BR Crane
Biochemistry 49 (18), 3824-3841, 2010
872010
BBA, a Derivative of 23-Hydroxybetulinic Acid, Potently Reverses ABCB1-Mediated Drug Resistance in Vitro and in Vivo
DM Zhang, C Shu, JJ Chen, K Sodani, J Wang, J Bhatnagar, P Lan, ...
Molecular pharmaceutics 9 (11), 3147-3159, 2012
502012
Assembly states of FliM and FliG within the flagellar switch complex
R Sircar, PP Borbat, MJ Lynch, J Bhatnagar, MS Beyersdorf, CJ Halkides, ...
Journal of molecular biology 427 (4), 867-886, 2015
462015
Rigid Body Refinement of Protein Complexes with Long‐Range Distance Restraints from Pulsed Dipolar ESR
J Bhatnagar, JH Freed, BR Crane
Methods in enzymology 423, 117-133, 2007
452007
The Interplay of Hydrophobic and Electrostatic Effects in the Surfactant-Induced Aggregation/Deaggregation of Chlorin p6
PP Mishra, J Bhatnagar, A Datta
The Journal of Physical Chemistry B 109 (51), 24225-24230, 2005
422005
Fluorescence monitoring of pH dependent complexation of chlorin p6 with surfactants
PP Mishra, J Bhatnagar, A Datta
Chemical physics letters 386 (1-3), 158-161, 2004
372004
Mutations in intracellular loops 1 and 3 lead to misfolding of human P-glycoprotein (ABCB1) that can be rescued by cyclosporine A, which reduces its association with chaperone …
K Kapoor, J Bhatnagar, EE Chufan, SV Ambudkar
Journal of Biological Chemistry 288 (45), 32622-32636, 2013
252013
Self-association of the histidine kinase CheA as studied by pulsed dipolar ESR spectroscopy
J Bhatnagar, R Sircar, PP Borbat, JH Freed, BR Crane
Biophysical journal 102 (9), 2192-2201, 2012
222012
Conserved Walker A cysteines 431 and 1074 in human P-glycoprotein are accessible to thiol-specific agents in the apo and ADP-vanadate trapped conformations
HM Sim, J Bhatnagar, EE Chufan, K Kapoor, SV Ambudkar
Biochemistry 52 (41), 7327-7338, 2013
102013
Mapping conformational changes associated with the catalytic cycle of human P-glycoprotein (ABCB1)
J Bhatnagar, HM Sim, E Georgieva, K Kapoor, E Chufan, S Ohnuma, ...
Biophysical Journal 102 (3), 606a-607a, 2012
12012
Correction to “BBA, a Derivative of 23-Hydroxybetulinic Acid, Potently Reverses ABCB1-Mediated Drug Resistance in Vitro and in Vivo
DM Zhang, C Shu, JJ Chen, K Sodani, J Wang, J Bhatnagar, P Lan, ...
Molecular Pharmaceutics 20 (6), 3249-3249, 2023
2023
An improved trispecific antibody (TsAb) platform for optimally engaging T cells for the treatment of solid tumor malignancies
R Nair, V Somasundaram, A Goswami, J Bhatnagar, S Paul, C Dey, ...
Cancer Research 83 (7_Supplement), 1864-1864, 2023
2023
BCA101, a novel tumor-targeted bifunctional fusion antibody simultaneously inhibiting EGFR and TGF-β signaling with potential for durable tumor growth inhibition
SR Boreddy, R Nair, PK Pandey, A Kuriakose, A Banerjee, C Dey, ...
Cancer Research 83 (7_Supplement), 6339-6339, 2023
2023
1368 A novel bispecific BCA356 targeting tumour antigen CAIX conjugated to an attenuated IL12 demonstrates pre-clinical efficacy with potential for limited systemic toxicity
P Nair, A Goswamy, J Bhatnagar, S Boreddy, R Nair, S Krishn, ...
Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022
2022
Probing accessibility and conformational changes in ATP-binding sites during the catalytic cycle of human P-glycoprotein (ABCB1).
HM Sim, J Bhatnagar, SA Green, A Gonzalez, EE Chufan, SV Ambudkar
Cancer Research 73 (8_Supplement), 898-898, 2013
2013
Role of intracellular loops 1 and 3 in folding and cell surface expression of human P-glycoprotein (ABCB1).
K Kapoor, J Bhatnagar, EE Chufan, SV Ambudkar
Cancer Research 73 (8_Supplement), 897-897, 2013
2013
Receptor Kinase Interactions In Bacterial Chemotaxis Revealed By Pulsed Dipolar Esr Spectroscopy
J Bhatnagar
2009
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