| Mitochondria, ER, and nuclear membrane defects reveal early mechanisms for upper motor neuron vulnerability with respect to TDP-43 pathology M Gautam, JH Jara, N Kocak, LE Rylaarsdam, KD Kim, EH Bigio, ... Acta neuropathologica 137, 47-69, 2019 | 74 | 2019 |
| MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology JH Jara, M Gautam, N Kocak, EF Xie, Q Mao, EH Bigio, PH Özdinler Journal of neuroinflammation 16, 1-16, 2019 | 57 | 2019 |
| Mitoautophagy: A unique self-destructive path mitochondria of upper motor neurons with TDP-43 pathology take, very early in ALS M Gautam, EF Xie, N Kocak, PH Ozdinler Frontiers in Cellular Neuroscience 13, 489, 2019 | 39 | 2019 |
| Improving mitochondria and ER stability helps eliminate upper motor neuron degeneration that occurs due to mSOD1 toxicity and TDP‐43 pathology B Genç, M Gautam, Ö Gözütok, I Dervishi, S Sanchez, GM Goshu, ... Clinical and Translational Medicine 11 (2), e336, 2021 | 22 | 2021 |
| Upper motor neurons are a target for gene therapy and UCHL1 is necessary and sufficient to improve cellular integrity of diseased upper motor neurons B Genç, JH Jara, SS Sanchez, AKB Lagrimas, Ö Gözütok, N Koçak, Y Zhu, ... Gene therapy 29 (3), 178-192, 2022 | 11 | 2022 |
| SBT-272 improves TDP-43 pathology in ALS upper motor neurons by modulating mitochondrial integrity, motility, and function M Gautam, B Genç, B Helmold, A Ahrens, J Kuka, M Makrecka-Kuka, ... Neurobiology of Disease 178, 106022, 2023 | 10 | 2023 |
| NU-9 improves health of hSOD1G93A mouse upper motor neurons in vitro, especially in combination with riluzole or edaravone B Genç, M Gautam, BR Helmold, N Koçak, A Günay, GM Goshu, ... Scientific reports 12 (1), 5383, 2022 | 5 | 2022 |
| Complex Neuroimmune Involvement in Neurodevelopment: A Mini-Review MC Monet, N Quan Journal of Inflammation Research, 2979-2991, 2023 | 4 | 2023 |
| Upper Motor Neurons are a Target for Gene Therapy and UCHL1 is Necessary and Sufficient to Improve Cellular Integrity of Diseased Upper Motor Neurons A Ahrens, B Genc, J Jara, S Sanchez, A Lagrimas, O Gozutok, N Kocak, ... MUSCLE & NERVE 66, S3-S4, 2022 | | 2022 |
| SBT-272 improved mitochondria structure and function and preserved Upper Motor Neurons with TDP-43 Pathology M Gautam, B Genc, A Gunay, N Kocak, B Helmold, A Ahrens, ... MUSCLE & NERVE 66, S2-S3, 2022 | | 2022 |
| SBT-272 improves TDP-43 pathology in the ALS motor cortex by modulating mitochondrial integrity, motility, and function M Gautam, B Genç, B Helmold, A Ahrens, J Kuka, M Makrecka-Kuka, ... bioRxiv, 2022.10. 04.510854, 2022 | | 2022 |
Mukesh GautamNorthwestern UniversityVerified email at northwestern.edu
