Discovery of new biosynthetic pathways: the lipid A story CRH Raetz, Z Guan, BO Ingram, DA Six, F Song, X Wang, J Zhao Journal of lipid research 50, S103-S108, 2009 | 274 | 2009 |
Discovery of a cardiolipin synthase utilizing phosphatidylethanolamine and phosphatidylglycerol as substrates BK Tan, M Bogdanov, J Zhao, W Dowhan, CRH Raetz, Z Guan Proceedings of the National Academy of Sciences 109 (41), 16504-16509, 2012 | 240 | 2012 |
Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis BC Chung, J Zhao, RA Gillespie, DY Kwon, Z Guan, J Hong, P Zhou, ... Science 341 (6149), 1012-1016, 2013 | 235 | 2013 |
Three phosphatidylglycerol-phosphate phosphatases in the inner membrane of Escherichia coli YH Lu, Z Guan, J Zhao, CRH Raetz Journal of biological chemistry 286 (7), 5506-5518, 2011 | 107 | 2011 |
A CRISPR-Cas system enhances envelope integrity mediating antibiotic resistance and inflammasome evasion TR Sampson, BA Napier, MR Schroeder, R Louwen, J Zhao, CY Chin, ... Proceedings of the National Academy of Sciences 111 (30), 11163-11168, 2014 | 106 | 2014 |
Structural basis of NPR1 in activating plant immunity S Kumar, R Zavaliev, Q Wu, Y Zhou, J Cheng, L Dillard, J Powers, ... Nature 605 (7910), 561-566, 2022 | 79 | 2022 |
Mutants resistant to LpxC inhibitors by rebalancing cellular homeostasis D Zeng, J Zhao, HS Chung, Z Guan, CRH Raetz, P Zhou Journal of Biological Chemistry 288 (8), 5475-5486, 2013 | 66 | 2013 |
Synthesis, structure, and antibiotic activity of aryl-substituted LpxC inhibitors X Liang, CJ Lee, J Zhao, EJ Toone, P Zhou Journal of medicinal chemistry 56 (17), 6954-6966, 2013 | 65 | 2013 |
Drug design from the cryptic inhibitor envelope CJ Lee, X Liang, Q Wu, J Najeeb, J Zhao, R Gopalaswamy, M Titecat, ... Nature communications 7 (1), 10638, 2016 | 63 | 2016 |
Removal of the outer Kdo from Helicobacter pylori lipopolysaccharide and its impact on the bacterial surface CM Stead, J Zhao, CRH Raetz, MS Trent Molecular microbiology 78 (4), 837-852, 2010 | 57 | 2010 |
In vivo and in vitro synthesis of phosphatidylglycerol by an Escherichia coli cardiolipin synthase C Li, BK Tan, J Zhao, Z Guan Journal of Biological Chemistry 291 (48), 25144-25153, 2016 | 55 | 2016 |
NaxD is a deacetylase required for lipid A modification and Francisella pathogenesis AC Llewellyn, J Zhao, F Song, J Parvathareddy, Q Xu, BA Napier, ... Molecular microbiology 86 (3), 611-627, 2012 | 52 | 2012 |
Structure, inhibition, and regulation of essential lipid A enzymes P Zhou, J Zhao Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2017 | 46 | 2017 |
A two‐component Kdo hydrolase in the inner membrane of Francisella novicida J Zhao, CRH Raetz Molecular microbiology 78 (4), 820-836, 2010 | 44 | 2010 |
Mutational Analysis of the Chemoreceptor-Coupling Domain of the Escherichia coli Chemotaxis Signaling Kinase CheA J Zhao, JS Parkinson Journal of bacteriology 188 (9), 3299-3307, 2006 | 39 | 2006 |
Cysteine-Scanning Analysis of the Chemoreceptor-Coupling Domain of the Escherichia coli Chemotaxis Signaling Kinase CheA J Zhao, JS Parkinson Journal of bacteriology 188 (12), 4321-4330, 2006 | 29 | 2006 |
Discovery of the elusive UDP-Diacylglucosamine hydrolase in the lipid A biosynthetic pathway in Chlamydia trachomatis HE Young, J Zhao, JR Barker, Z Guan, RH Valdivia, P Zhou MBio 7 (2), 10.1128/mbio. 00090-16, 2016 | 23 | 2016 |
Structural basis of the UDP-diacylglucosamine pyrophosphohydrolase LpxH inhibition by sulfonyl piperazine antibiotics J Cho, M Lee, CS Cochrane, CG Webster, BA Fenton, J Zhao, J Hong, ... Proceedings of the National Academy of Sciences 117 (8), 4109-4116, 2020 | 22 | 2020 |
Structure of the essential Haemophilus influenzae UDP-diacylglucosamine pyrophosphohydrolase LpxH in lipid A biosynthesis J Cho, CJ Lee, J Zhao, HE Young, P Zhou Nature microbiology 1 (11), 1-4, 2016 | 19 | 2016 |
Metabolic engineering of Escherichia coli to produce a monophosphoryl lipid A adjuvant Y Ji, J An, D Hwang, SM Lim, C Lee, J Zhao, HK Song, EG Yang, P Zhou, ... Metabolic engineering 57, 193-202, 2020 | 18 | 2020 |