| The association between sterilizing activity and drug distribution into tuberculosis lesions B Prideaux, LE Via, MD Zimmerman, S Eum, J Sarathy, P O'brien, C Chen, ... Nature medicine 21 (10), 1223-1227, 2015 | 471 | 2015 |
| Pyrazinamide resistance is caused by two distinct mechanisms: prevention of coenzyme A depletion and loss of virulence factor synthesis P Gopal, M Yee, J Sarathy, JL Low, JP Sarathy, F Kaya, V Dartois, ... ACS infectious diseases 2 (9), 616-626, 2016 | 98 | 2016 |
| Ethambutol partitioning in tuberculous pulmonary lesions explains its clinical efficacy M Zimmerman, J Lestner, B Prideaux, P O'Brien, I Dias-Freedman, ... Antimicrobial agents and chemotherapy 61 (9), 10.1128/aac. 00924-17, 2017 | 79 | 2017 |
| Pyrazinoic acid inhibits mycobacterial coenzyme A biosynthesis by binding to aspartate decarboxylase PanD P Gopal, W Nartey, P Ragunathan, J Sarathy, F Kaya, M Yee, C Setzer, ... ACS infectious diseases 3 (11), 807-819, 2017 | 75 | 2017 |
| Whole-cell screen of fragment library identifies gut microbiota metabolite indole propionic acid as antitubercular DA Negatu, JJJ Liu, M Zimmerman, F Kaya, V Dartois, CC Aldrich, ... Antimicrobial agents and chemotherapy 62 (3), 10.1128/aac. 01571-17, 2018 | 71 | 2018 |
| Selective inactivity of pyrazinamide against tuberculosis in C3HeB/FeJ mice is best explained by neutral pH of caseum JP Lanoix, T Ioerger, A Ormond, F Kaya, J Sacchettini, V Dartois, ... Antimicrobial agents and chemotherapy 60 (2), 735-743, 2016 | 69 | 2016 |
| Matrix metalloproteinase inhibitors enhance the efficacy of frontline drugs against Mycobacterium tuberculosis Y Xu, L Wang, MD Zimmerman, KY Chen, L Huang, DJ Fu, F Kaya, ... PLoS pathogens 14 (4), e1006974, 2018 | 64 | 2018 |
| Fluoroquinolone efficacy against tuberculosis is driven by penetration into lesions and activity against resident bacterial populations J Sarathy, L Blanc, N Alvarez-Cabrera, P O’brien, I Dias-Freedman, ... Antimicrobial agents and chemotherapy 63 (5), 10.1128/aac. 02516-18, 2019 | 53 | 2019 |
| Comparative analysis of pharmacodynamics in the C3HeB/FeJ mouse tuberculosis model for DprE1 inhibitors TBA-7371, PBTZ169, and OPC-167832 GT Robertson, ME Ramey, LM Massoudi, CL Carter, M Zimmerman, ... Antimicrobial agents and chemotherapy 65 (11), 10.1128/aac. 00583-21, 2021 | 42 | 2021 |
| Tissue distribution of doxycycline in animal models of tuberculosis M Gengenbacher, MD Zimmerman, JP Sarathy, F Kaya, H Wang, M Mina, ... Antimicrobial agents and chemotherapy 64 (5), 10.1128/aac. 02479-19, 2020 | 28 | 2020 |
| Early bactericidal activity trial of nitazoxanide for pulmonary tuberculosis KF Walsh, K McAulay, MH Lee, SC Vilbrun, L Mathurin, D Jean Francois, ... Antimicrobial agents and chemotherapy 64 (5), 10.1128/aac. 01956-19, 2020 | 26 | 2020 |
| A rabbit model to study antibiotic penetration at the site of infection for nontuberculous mycobacterial lung disease: macrolide case study F Kaya, JP Ernest, K LoMauro, M Gengenbacher, A Madani, WW Aragaw, ... Antimicrobial agents and chemotherapy 66 (3), e02212-21, 2022 | 14 | 2022 |
| Lesion penetration and activity limit the utility of second-line injectable agents in pulmonary tuberculosis JP Ernest, J Sarathy, N Wang, F Kaya, MD Zimmerman, N Strydom, ... Antimicrobial agents and chemotherapy 65 (10), 10.1128/aac. 00506-21, 2021 | 14 | 2021 |
| Pharmacokinetics and target attainment of SQ109 in plasma and human-like tuberculosis lesions in rabbits O Egbelowo, JP Sarathy, K Gausi, MD Zimmerman, H Wang, GJ Wijnant, ... Antimicrobial agents and chemotherapy 65 (9), 10.1128/aac. 00024-21, 2021 | 14 | 2021 |
| Correlative imaging of trace elements and intact molecular species in a single-tissue sample at the 50 μm scale JM de Jesus, C Costa, A Burton, V Palitsin, R Webb, A Taylor, C Nikula, ... Analytical Chemistry 93 (40), 13450-13458, 2021 | 10 | 2021 |
| On-slide heat sterilization enables mass spectrometry imaging of tissue infected with high-threat pathogens outside of biocontainment: a study directed at mycobacterium … N Wang, JP Sarathy, M Zimmerman, F Kaya, H Wang, V Dartois, ... Journal of the American Society for Mass Spectrometry 32 (11), 2664-2674, 2021 | 6 | 2021 |
| Colocation of lipids, drugs, and metal Biomarkers using spatially Resolved lipidomics with elemental mapping HM Lewis, C Costa, V Dartois, F Kaya, M Chambers, J de Jesus, ... Analytical Chemistry 94 (34), 11798-11806, 2022 | 5 | 2022 |
| Lung microenvironments harbor Mycobacterium tuberculosis phenotypes with distinct treatment responses ND Walter, JP Ernest, C Dide-Agossou, AA Bauman, ME Ramey, ... Antimicrobial Agents and Chemotherapy 67 (9), e00284-23, 2023 | 2 | 2023 |
| Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities HIM Boshoff, K Young, YM Ahn, VD Yadav, BM Crowley, L Yang, J Su, ... ACS Infectious Diseases, 2024 | | 2024 |
| Normalizing granuloma vasculature and matrix improves drug delivery and reduces bacterial burden in tuberculosis-infected rabbits M Datta, LE Via, V Dartois, DM Weiner, M Zimmerman, F Kaya, AM Walker, ... Proceedings of the National Academy of Sciences 121 (14), e2321336121, 2024 | | 2024 |
Chao ChenRutgers UniversityVerified email at njms.rutgers.edu
Chao ChenRutgers UniversityVerified email at njms.rutgers.edu