Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission A Escalera, AS Gonzalez-Reiche, S Aslam, I Mena, M Laporte, RL Pearl, ... Cell host & microbe 30 (3), 373-387. e7, 2022 | 146 | 2022 |
Airway proteases: an emerging drug target for influenza and other respiratory virus infections M Laporte, L Naesens Current Opinion in Virology 24, 16-24, 2017 | 121 | 2017 |
The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways M Laporte, V Raeymaekers, R Van Berwaer, J Vandeput, ... PLoS pathogens 17 (4), e1009500, 2021 | 118 | 2021 |
CCL20, a direct-acting pro-angiogenic chemokine induced by hepatitis C virus (HCV): Potential role in HCV-related liver cancer M Benkheil, M Van Haele, T Roskams, M Laporte, S Noppen, K Abbasi, ... Experimental Cell Research 372 (2), 168-177, 2018 | 50 | 2018 |
Influenza virus entry via the GM3 ganglioside-mediated platelet-derived growth factor receptor β signalling pathway P Vrijens, S Noppen, T Boogaerts, E Vanstreels, R Ronca, P Chiodelli, ... Journal of General Virology 100 (4), 583-601, 2019 | 41 | 2019 |
Hemagglutinin cleavability, acid stability, and temperature dependence optimize influenza B virus for replication in human airways M Laporte, A Stevaert, V Raeymaekers, T Boogaerts, I Nehlmeier, W Chiu, ... Journal of virology 94 (1), 10.1128/jvi. 01430-19, 2019 | 40 | 2019 |
SARS-CoV-2 variants of concern have acquired mutations associated with an increased spike cleavage A Escalera, AS Gonzalez-Reiche, S Aslam, I Mena, RL Pearl, M Laporte, ... bioRxiv, 2021.08. 05.455290, 2021 | 18 | 2021 |
N-benzyl 4, 4-disubstituted piperidines as a potent class of influenza H1N1 virus inhibitors showing a novel mechanism of hemagglutinin fusion peptide interaction S de Castro, T Ginex, E Vanderlinden, M Laporte, A Stevaert, J Cumella, ... European Journal of Medicinal Chemistry 194, 112223, 2020 | 13 | 2020 |
The oral drug nitazoxanide restricts SARS-CoV-2 infection and attenuates disease pathogenesis in Syrian hamsters L Miorin, CE Mire, S Ranjbar, AJ Hume, J Huang, NA Crossland, ... bioRxiv, 2022.02. 08.479634, 2022 | 12 | 2022 |
Development of a robust and convenient dual-reporter high-throughput screening assay for SARS-CoV-2 antiviral drug discovery W Chiu, J Schepers, T Francken, L Vangeel, K Abbasi, D Jochmans, ... Antiviral research 210, 105506, 2023 | 6 | 2023 |
Impact of SARS-CoV-2 spike mutations on its activation by TMPRSS2 and the alternative TMPRSS13 protease A Stevaert, R Van Berwaer, C Mestdagh, J Vandeput, E Vanstreels, ... Mbio 13 (4), e01376-22, 2022 | 3 | 2022 |
The impact of S2 mutations on Omicron SARS-CoV-2 cell surface expression and fusogenicity A Escalera, M Laporte, S Turner, U Karakus, AS Gonzalez-Reiche, ... Emerging microbes & infections 13 (1), 2297553, 2024 | 1 | 2024 |
Breakthrough infections by SARS-CoV-2 variants boost cross-reactive hybrid immune responses in mRNA-vaccinated Golden Syrian hamsters JGB Diego, G Singh, S Jangra, K Handrejk, M Laporte, LA Chang, ... PLoS pathogens 20 (1), e1011805, 2024 | 1 | 2024 |
Antiviral strategies for epidemic and pandemic preparedness D Jochmans, M Laporte, J Neyts Cell Host & Microbe 31 (6), 856-860, 2023 | 1 | 2023 |
SARS-CoV-2 spike-glycoprotein processing at S1/S2 and S2’and shedding of the ACE2 viral receptor: roles of Furin and TMPRSS2 and implications for viral infectivity and cell-to … R Essalmani, J Jain, D Susan-Resiga, U Andréo, A Evagelidis, ... | 1 | 2020 |
Evidence for influenza B virus hemagglutinin adaptation to the human host: high cleavability, acid-stability and preference for cool temperature M Laporte, A Stevaert, V Raeymaekers, T Boogaerts, I Nehlmeier, W Chiu, ... bioRxiv, 736678, 2019 | 1 | 2019 |
Hemagglutinin cleavage profiles of human influenza A and B viruses, including that of 1918 influenza M Laporte, M Benkheil, A Stevaert, L Naesens VIB conference: The 1918 influenza pandemic: Historical and biomedical …, 2019 | 1 | 2019 |
Structure based development of Plasmodium hypoxanthine-guanine phosphoribosyltransferase inhibitors: a proof of concept study M Laporte Belgian Society for Microbiology and the National Committee for Microbiology …, 2014 | 1 | 2014 |
A robust mouse model of human parainfluenza 3 virus infection and efficacy of GS-441524, the parent nucleoside of remdesivir, against lung pathology J Neyts, Y Lin, M Khan, B Weynand, M Laporte, F Coenjaerts, D Babusis, ... | | 2024 |
Efficacy of Integrase Strand Transfer Inhibitors and the Capsid Inhibitor Lenacapavir against HIV-2 IW Kiarie, G Hoffka, M Laporte, P Leyssen, J Neyts, J Tőzsér, M Mahdi Preprints, 2024 | | 2024 |