| Cyclin-dependent kinase inhibitor P1446A induces apoptosis in a JNK/p38 MAPK-dependent manner in chronic lymphocytic leukemia B-cells C Paiva, JC Godbersen, RS Soderquist, T Rowland, S Kilmarx, ... PLoS One 10 (11), e0143685, 2015 | 41 | 2015 |
| SYK inhibition thwarts the BAFF-B-cell receptor crosstalk and thereby antagonizes Mcl-1 in chronic lymphocytic leukemia C Paiva, TA Rowland, B Sreekantham, C Godbersen, SR Best, P Kaur, ... Haematologica 102 (11), 1890, 2017 | 34 | 2017 |
| Pevonedistat, a Nedd8-activating enzyme inhibitor, sensitizes neoplastic B-cells to death receptor-mediated apoptosis C Paiva, JC Godbersen, T Rowland, OV Danilova, C Danes, A Berger, ... Oncotarget 8 (13), 21128, 2017 | 16 | 2017 |
| Selective targeting cyclin-dependent kinase-9 (CDK9) downmodulates c-MYC and induces apoptosis in diffuse large B-cell lymphoma (DLBCL) cells T Rowland, C Paiva, J Rowley, A Chen, L Drew, P Hurlin, BH Chang, ... Blood 128 (22), 289, 2016 | 11 | 2016 |
| Pharmacologic inhibition of SUMO-activating enzyme (SAE) with TAK-981 augments interferon signaling and regulates T cell differentiation in ex vivo studies of chronic … V Lam, SR Best, N Bruss, T Liu, TH Rowland, D Huszar, A Danilov Blood 134, 1760, 2019 | 5 | 2019 |
| SYK inhibitor entospletinib in combination with Obinutuzumab demonstrates efficacy in patients with relapsed/refractory chronic lymphocytic leukemia (CLL) AS Kittai, SR Best, B Thurlow, B Gokcora, A Stadnik, R MacKinnon, ... Blood 134, 4295, 2019 | 3 | 2019 |
| TAK-243, a small molecule inhibitor of ubiquitin-activating enzyme (UAE), induces ER stress and apoptosis in diffuse large B-cell lymphoma (DLBCL) cells SR Best, C Paiva, T Rowland, B Sreekantham, SE Spurgeon, A Berger, ... Blood 130, 1533, 2017 | 2 | 2017 |
| TAK-243, a Small Molecule Inhibitor of Ubiquitin-Activating Enzyme (UAE), Induces ER Stress and Apoptosis in CLL Cells SR Best, T Rowland, C Paiva, N Bruss, SE Spurgeon, A Berger, ... Blood 132, 1867, 2018 | 1 | 2018 |
| Pevonedistat, a small molecule inhibitor of NEDD8-activating enzyme (NAE), induces cell cycle deregulation, anaphase catastrophe, and apoptosis in T-cell lymphoma cells A Kittai, SR Best, T Rowland, N Bruss, C Okada, AV Danilov Blood 132, 1667, 2018 | 1 | 2018 |
| Selective targeting cyclin-dependent kinase-9 (CDK9) antagonizes survival of neoplastic B-cells via deregulation of c-MYC and MCL-1 A Danilov, T Rowland, C Paiva, S Best, B Sreekantham, J Rowley, ... LEUKEMIA & LYMPHOMA 58, 25-26, 2017 | 1 | 2017 |
| SYK Inhibition Disrupts the Cross-Talk Between B-Cell Activation Factor (BAFF) and B-Cell Receptor (BCR) and Thereby Antagonizes Mcl-1 in Chronic Lymphocytic Leukemia (CLL) B-Cells C Paiva, T Rowland, O Danilova, B Sreekantham, SE Spurgeon, ... Blood 128 (22), 303, 2016 | 1 | 2016 |
| Neddylation Pathway Regulates Treg Differentiation and T Cell Function in Chronic Lymphocytic Leukemia (CLL) Ex Vivo and Murine In Vivo Studies SR Best, V Lam, N Bruss, TH Rowland, AS Kittai, T Liu, AJ Berger, ... Blood 134, 4313, 2019 | | 2019 |
| Immunomodulatory Effects of Pevonedistat, a NEDD8-Activating Enzyme (NAE) Inhibitor, in Chronic Lymphocytic Leukemia (CLL) SR Best, A Kittai, T Rowland, N Bruss, SE Spurgeon, A Berger, A Moran, ... Blood 132, 2946, 2018 | | 2018 |
| THERAPEUTIC DISRUPTION OF THE BAFF-B-CELL RECEPTOR CROSSTALK IN CHRONIC LYMPHOCYTIC LEUKEMIA CELLS C Paiva, T Rowland, B Sreekantham, O Danilova, A Danilov HAEMATOLOGICA 102, 10-10, 2017 | | 2017 |
