| Ancestral diterpene cyclases show increased thermostability and substrate acceptance NM Hendrikse, G Charpentier, E Nordling, PO Syrén The FEBS journal 285 (24), 4660-4673, 2018 | 40 | 2018 |
| Engineering of ancestors as a tool to elucidate structure, mechanism, and specificity of extant terpene cyclase K Schriever, P Saenz-Mendez, RS Rudraraju, NM Hendrikse, EP Hudson, ... Journal of the American Chemical Society 143 (10), 3794-3807, 2021 | 36 | 2021 |
| Exploring the therapeutic potential of modern and ancestral phenylalanine/tyrosine ammonia-lyases as supplementary treatment of hereditary tyrosinemia NM Hendrikse, A Holmberg Larsson, S Svensson Gelius, S Kuprin, ... Scientific Reports 10 (1), 1315, 2020 | 32 | 2020 |
| Affinity maturation of a cyclic peptide handle for therapeutic antibodies using deep mutational scanning M van Rosmalen, BMG Janssen, NM Hendrikse, AJ van der Linden, ... Journal of Biological Chemistry 292 (4), 1477-1489, 2017 | 23 | 2017 |
| Biomarker qualification at the European medicines agency: a review of biomarker qualification procedures from 2008 to 2020 E Bakker, NM Hendrikse, F Ehmann, DS Van der Meer, J Llinares Garcia, ... Clinical Pharmacology & Therapeutics 112 (1), 69-80, 2022 | 21 | 2022 |
| Directed evolution of the 3C protease from coxsackievirus using a novel fluorescence-assisted intracellular method SW Meister, NM Hendrikse, J Löfblom Biological Chemistry 400 (3), 405-415, 2019 | 18 | 2019 |
| Virtual screening of potential anticancer drugs based on microbial products GP Pinto, NM Hendrikse, J Stourac, J Damborsky, D Bednar Seminars in Cancer Biology 86, 1207-1217, 2022 | 10 | 2022 |
| Biomarkers in medicines development—From discovery to regulatory qualification and beyond NM Hendrikse, J Llinares Garcia, T Vetter, AJ Humphreys, F Ehmann Frontiers in Medicine 9, 878942, 2022 | 9 | 2022 |
| Ancestral lysosomal enzymes with increased activity harbor therapeutic potential for treatment of Hunter syndrome NM Hendrikse, A Sandegren, T Andersson, J Blomqvist, Å Makower, ... Iscience 24 (3), 2021 | 5 | 2021 |
| Engineering enzymes towards biotherapeutic applications using ancestral sequence reconstruction N Hendrikse KTH Royal Institute of Technology, 2020 | | 2020 |
| Exploring the potential of ancestral phenylalanine/tyrosine ammonia-lyases for therapeutic applications N Marie Hendrikse, A Holmberg Larsson, PO Syrén, S Kuprin, E Nordling, ... | | 2019 |
| Engineering substrate specificity into a promiscuous ancestral diterpene synthase K Schriever, NM Hendrikse, P Saénz-Mendez, A Biundo, PO Syrén | | 2019 |
| Computational Techniques for Efficient Biocatalysis POS Ionnis V. Pavlidis, Natalie M. Hendrikse Modern Biocatalysis: Advances Towards Sythetic Biological Systems 32, 119-147, 2018 | | 2018 |
| Redesign of biosynthetic enzymes using ancestral sequence reconstruction NM Hendrikse, P Strömberg, E Nordling, PO Syrén The FEBS Journal 284 (Supplement 1 - 42nd FEBS Congress), 86-87, 2017 | | 2017 |
| Development of a Novel Selection Method for Protease Engineering: A high-throughput fluorescent reporter-based method for characterization and selection of proteases N Hendrikse | | 2016 |
| Bioluminescent sensor proteins for therapeutic drug monitoring of the monoclonal antibody Cetuximab M Van Rosmalen, R Arts, B Janssen, N Hendrikse, D Wanders, M Merkx PROTEIN SCIENCE 24, 220-220, 2015 | | 2015 |
