ecDNA hubs drive cooperative intermolecular oncogene expression KL Hung, KE Yost, L Xie, Q Shi, K Helmsauer, J Luebeck, R Schöpflin, ... Nature 600 (7890), 731-736, 2021 | 147 | 2021 |
Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH KL Hung, J Luebeck, SR Dehkordi, CI Colón, R Li, ITL Wong, C Coruh, ... Nature genetics 54 (11), 1746-1754, 2022 | 51 | 2022 |
Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug J Bi, A Khan, J Tang, AM Armando, S Wu, W Zhang, RC Gimple, A Reed, ... Cell reports 37 (5), 2021 | 47 | 2021 |
Overexpression of iASPP is required for autophagy in response to oxidative stress in choriocarcinoma KK Chan, ESY Wong, ITL Wong, CLY Cheung, OGW Wong, HYS Ngan, ... BMC cancer 19, 1-13, 2019 | 7 | 2019 |
Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma OS Chapman, J Luebeck, S Sridhar, ITL Wong, D Dixit, S Wang, G Prasad, ... Nature genetics 55 (12), 2189-2199, 2023 | 4 | 2023 |
KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss G Kauwe, KA Pareja-Navarro, L Yao, JH Chen, I Wong, R Saloner, ... The Journal of Clinical Investigation 134 (3), 2024 | 2 | 2024 |
Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers J Tang, NE Weiser, G Wang, S Chowdhry, EJ Curtis, Y Zhao, ITL Wong, ... bioRxiv, 2024.03. 29.586681, 2024 | | 2024 |
CoRAL accurately resolves extrachromosomal DNA genome structures with long-read sequencing K Zhu, MG Jones, J Luebeck, X Bu, H Yi, KL Hung, ITL Wong, S Zhang, ... bioRxiv, 2024.02. 15.580594, 2024 | | 2024 |
Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change SR Dehkordi, ITL Wong, J Ni, J Luebeck, K Zhu, G Prasad, ... bioRxiv, 2023 | | 2023 |
Disparate pathways for extrachromosomal DNA biogenesis and genomic DNA repair JC Rose, ITL Wong, B Daniel, MG Jones, KE Yost, KL Hung, EJ Curtis, ... bioRxiv, 2023 | | 2023 |
Coordinated inheritance of extrachromosomal DNA species in human cancer cells KL Hung, MG Jones, ITL Wong, JT Lange, J Luebeck, E Scanu, BJ He, ... bioRxiv, 2023 | | 2023 |
OMIC-01. THE LANDSCAPE OF EXTRACHROMOSOMAL CIRCULAR DNA IN MEDULLOBLASTOMA SUBGROUPS O Chapman, J Luebeck, S Wang, A Garancher, J Larson, J Lange, ... Neuro-oncology 23 (Supplement_1), i37-i37, 2021 | | 2021 |
NUAK2 is highly overexpressed in ovarian cancer and the overexpression of its nuclear form correlates with tumor aggressiveness L Chen, OGW Wong, ITL Wong, ANY Cheung Cancer Research 80 (16_Supplement), 5906-5906, 2020 | | 2020 |
NANOG sustains ovarian cancer cell survival and disrupts ER stress signaling through BiP/PERK under glutamine depletion AMY Suen, ITL Wong, CYS Tse, KK Chan, OGW Wong, ANY Cheung Cancer Research 80 (16_Supplement), 2565-2565, 2020 | | 2020 |
Genome-wide profiling of PAK4 DNA-binding sites and transcriptome reveals its potential transcriptional control on DNA repair-related genes in ovarian cancer cells ITL Wong, OGW Wong, Y Qin, J Wang, ANY Cheung Cancer Research 77 (13_Supplement), 2419-2419, 2017 | | 2017 |
Molecular studies on EGFR and PAK4 in ovarian carcinogenesis T Wong HKU Theses Online (HKUTO), 2017 | | 2017 |
The miR-143 target TARDBP as a marker for cervical cancer OGW Wong, ITL Wong, CKW Wong, OKL Tsun, ANY Cheung European Journal of Cancer 60, e6-e7, 2016 | | 2016 |
Dysregulation of miR-143 in cervical cancer GW Wong, IT Wong, TC Chu, HYS Ngan, ANY Cheung Conference of Asia Oceania Research Organization on Genital Infection and …, 2012 | | 2012 |
Cellular role of miR-143 in cervical cancer T Wong HKU Theses Online (HKUTO), 2012 | | 2012 |