A prominent glycyl radical enzyme in human gut microbiomes metabolizes trans-4-hydroxy-L-proline BJ Levin*, YY Huang*, SC Peck, Y Wei, A Martinez-Del Campo, JA Marks, ... Science 355 (6325), eaai8386, 2017 | 151 | 2017 |
PKMζ is essential for spinal plasticity underlying the maintenance of persistent pain A Laferrière, MH Pitcher, A Haldane, Y Huang, V Cornea, N Kumar, ... Molecular pain 7 (1), 99, 2011 | 72 | 2011 |
Anaerobic 4-hydroxyproline utilization: discovery of a new glycyl radical enzyme in the human gut microbiome uncovers a widespread microbial metabolic activity YY Huang, A Martínez-del Campo, EP Balskus Gut microbes 9 (5), 437-451, 2018 | 38 | 2018 |
Site-specific fluorescent labeling and oriented immobilization of a triple mutant of CYP3A4 via C64 A Ménard, Y Huang, P Karam, G Cosa, K Auclair Bioconjugate chemistry 23 (4), 826-836, 2012 | 25 | 2012 |
Molecular basis for catabolism of the abundant metabolite trans-4-hydroxy-L-proline by a microbial glycyl radical enzyme LRF Backman*, YY Huang*, MC Andorfer, B Gold, RT Raines, EP Balskus, ... eLife 9, e51420, 2020 | 17 | 2020 |
Antibiotic binding drives catalytic activation of aminoglycoside kinase APH (2 ″)-Ia SJ Caldwell, Y Huang, AM Berghuis Structure 24 (6), 935-945, 2016 | 16 | 2016 |
Type II ligands as chemical auxiliaries to favor enzymatic transformations by P450 2E1 A Ménard, C Fabra, Y Huang, K Auclair ChemBioChem 13 (17), 2527-2536, 2012 | 15 | 2012 |
Barcoded overexpression screens in gut Bacteroidales identify genes with new roles in carbon utilization and stress resistance YY Huang, MN Price, A Hung, O Gal-Oz, D Ho, H Carion, ... BioRxiv, 2022.10. 10.511384, 2022 | 9* | 2022 |
The Stickland Reaction Precursor trans-4-Hydroxy-l-Proline Differentially Impacts the Metabolism of Clostridioides difficile and Commensal Clostridia AD Reed, JR Fletcher, YY Huang, R Thanissery, AJ Rivera, RJ Parsons, ... Msphere 7 (2), e00926-21, 2022 | 9 | 2022 |
Genetic Predictive Factors for Nonsusceptible Phenotypes and Multidrug Resistance in Expanded-Spectrum Cephalosporin-Resistant Uropathogenic Escherichia coli from a Multicenter … N Jackson, CR Belmont, NJ Tarlton, YH Allegretti, S Adams-Sapper, ... Msphere, e00471-22, 2022 | 3 | 2022 |
Barcoded overexpression screens in gut Bacteroidales identify genes with new roles in carbon utilization and stress resistance YY Huang, MN Price, A Hung, O Gal-Oz, D Ho, H Carion, ... bioRxiv, 2023 | | 2023 |
Structurally investigating a niche pathway for chemical reversal of proline hydroxylation in the pathogen Clostridioides difficile LRF Backman, YY Huang, MC Andorfer, B Gold, RT Raines, EP Balskus, ... The FASEB Journal 36, 2022 | | 2022 |
Structural Characterization of a Hydroxyproline Dehydratase from C. difficile L Backman, Y Huang, M Andorfer, B Gold, R Raines, E Balskus, ... PROTEIN SCIENCE 30, 20-20, 2021 | | 2021 |
Chemical tools to decipher gut microbial communities: Detection and characterisation of putative glycyl radical enzymes (GREs) M Luescher, Y Huang, E Balskus ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
Anaerobic 4-Hydroxyproline Metabolism by a Widespread Microbial Glycyl Radical Enzyme YY Huang, L Backman, B Gold, RT Raines, CL Drennan, EP Balskus The FASEB Journal 32 (1_supplement), 534.16-534.16, 2018 | | 2018 |
Characterization of encystation and excystation in a microbial eukaryote, Nuclearia simplex YY Huang | | |