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Bing Kuang
Bing Kuang
Verified email at pfizer.com
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Year
A Protein Interaction Map of Drosophila melanogaster
L Giot, JS Bader, C Brouwer, A Chaudhuri, B Kuang, Y Li, YL Hao, CE Ooi, ...
science 302 (5651), 1727-1736, 2003
28792003
A Drosophila protein-interaction map centered on cell-cycle regulators
CA Stanyon, G Liu, BA Mangiola, N Patel, L Giot, B Kuang, H Zhang, ...
Genome biology 5, 1-14, 2004
2402004
Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration
JD Ding, LV Johnson, R Herrmann, S Farsiu, SG Smith, M Groelle, ...
Proceedings of the National Academy of Sciences 108 (28), E279-E287, 2011
2262011
CR011, a fully human monoclonal antibody-auristatin E conjugate, for the treatment of melanoma.
KF Tse, M Jeffers, VA Pollack, DA McCabe, ML Shadish, NV Khramtsov, ...
Clinical cancer research: an official journal of the American Association …, 2006
2252006
A genetic screen for novel components of the Ras/Mitogen-activated protein kinase signaling pathway that interact with the yan gene of Drosophila identifies split ends, a new …
I Rebay, F Chen, F Hsiao, PA Kolodziej, BH Kuang, T Laverty, C Suh, ...
Genetics 154 (2), 695-712, 2000
1562000
split ends encodes large nuclear proteins that regulate neuronal cell fate and axon extension in the Drosophila embryo
B Kuang, SCY Wu, YA Shin, L Luo, P Kolodziej
Development 127 (7), 1517-1529, 2000
992000
Therapeutic monoclonal antibody concentration monitoring: free or total?
B Kuang, L King, HF Wang
Bioanalysis 2 (6), 1125-1140, 2010
972010
Fluorescence probing of yeast actin subdomain 3/4 hydrophobic loop 262–274: actin-actin and actin-myosin interactions in actin filaments
L Feng, E Kim, WL Lee, CJ Miller, B Kuang, E Reisler, PA Rubenstein
Journal of Biological Chemistry 272 (27), 16829-16837, 1997
891997
Beryllium fluoride and phalloidin restore polymerizability of a mutant yeast actin (V266G, L267G) with severely decreased hydrophobicity in a subdomain 3/4 loop
B Kuang, PA Rubenstein
Journal of Biological Chemistry 272 (2), 1237-1247, 1997
511997
A mathematical model of the effect of immunogenicity on therapeutic protein pharmacokinetics
X Chen, T Hickling, E Kraynov, B Kuang, C Parng, P Vicini
The AAPS journal 15, 1141-1154, 2013
482013
The effects of severely decreased hydrophobicity in a subdomain 3/4 loop on the dynamics and stability of yeast G-actin
B Kuang, PA Rubenstein
Journal of Biological Chemistry 272 (7), 4412-4418, 1997
421997
A phase I study of CR002, a fully-human monoclonal antibody against platelet-derived growth factor-D.
T Hawthorne, L Giot, L Blake, B Kuang, R Gerwien, G Smithson, W Hahne, ...
International journal of clinical pharmacology and therapeutics 46 (5), 236-244, 2008
392008
Tropomyosin-dependent filament formation by a polymerization-defective mutant yeast actin (V266G, L267G)
KK Wen, B Kuang, PA Rubenstein
Journal of Biological Chemistry 275 (51), 40594-40600, 2000
382000
How current understanding of clearance mechanisms and pharmacodynamics of therapeutic proteins can be applied for evaluation of their drug-drug interaction potential
E Kraynov, SW Martin, S Hurst, OA Fahmi, M Dowty, C Cronenberger, ...
Drug metabolism and disposition 39 (10), 1779-1783, 2011
322011
Modeling, simulation, and translation framework for the preclinical development of monoclonal antibodies
KT Luu, E Kraynov, B Kuang, P Vicini, WZ Zhong
The AAPS journal 15, 551-558, 2013
292013
Enhancing antisense efficacy with multimers and multi-targeting oligonucleotides (MTOs) using cleavable linkers
RR Subramanian, MA Wysk, KM Ogilvie, A Bhat, B Kuang, TD Rockel, ...
Nucleic Acids Research 43 (19), 9123-9132, 2015
272015
RL, KP White, M
L Giot, JS Bader, C Brouwer, A Chaudhuri, B Kuang, Y Li, YL Hao, CE Ooi, ...
Braverman, T. Jarvie, S. Gold, M. Leach, J. Knight, RA Shimkets, MP McKenna …, 2003
172003
Pharmacokinetics, pharmacodynamics, and toxicity of a PD-1-targeted IL-15 in cynomolgus monkeys
C Ji, B Kuang, BS Buetow, A Vitsky, Y Xu, TH Huang, J Chaparro-Riggers, ...
Plos one 19 (2), e0298240, 2024
2024
Recent advances in the bioanalysis of peptide and protein therapeutics
B Kuang, S Fountain
Future Science Ltd, 2013
2013
Restoration of polymerization to a polymerization defective yeast actin by tropomyosin and a mutant tropomyosin missing internal repeats 2-4.
KK Wen, B Kuang, PA Rubenstein
BIOPHYSICAL JOURNAL 74 (2), A47-A47, 1998
1998
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Articles 1–20