Discovery of 5-(methylthio) pyrimidine derivatives as L858R/T790M mutant selective epidermal growth factor receptor (EGFR) inhibitors Q Xiao, R Qu, D Gao, Q Yan, L Tong, W Zhang, J Ding, H Xie, Y Li Bioorganic & medicinal chemistry 24 (12), 2673-2680, 2016 | 21 | 2016 |
Semi-synthesis of a series natural flavonoids and flavonoid glycosides from scutellarin S Yan, M Xie, Y Wang, Q Xiao, N Ding, Y Li Tetrahedron 76 (8), 130950, 2020 | 20 | 2020 |
Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors D Gao, N Jin, Y Fu, Y Zhu, Y Wang, T Wang, Y Chen, M Zhang, Q Xiao, ... European Journal of Medicinal Chemistry, 113333, 2021 | 16 | 2021 |
Design, synthesis and biological evaluation of benzyloxyphenyl-methylaminophenol derivatives as STAT3 signaling pathway inhibitors D Gao, Q Xiao, M Zhang, Y Li Bioorganic & medicinal chemistry 24 (11), 2549-2558, 2016 | 15 | 2016 |
Stapling of two PEGylated side chains increases the conformational stability of the WW domain via an entropic effect Q Xiao, NA Bécar, NP Brown, MS Smith, KL Stern, SRE Draper, ... Organic & biomolecular chemistry 16 (46), 8933-8939, 2018 | 14 | 2018 |
Polyethylene Glycol Based Changes to β-Sheet Protein Conformational and Proteolytic Stability Depend on Conjugation Strategy and Location SRE Draper, PB Lawrence, WM Billings, Q Xiao, NP Brown, NA Bécar, ... Bioconjugate chemistry 28 (10), 2507-2513, 2017 | 12 | 2017 |
Influence of PEGylation on the strength of protein surface salt bridges Q Xiao, SRE Draper, MS Smith, N Brown, NAB Pugmire, DS Ashton, ... ACS chemical biology, 2019 | 10 | 2019 |
Long-range PEG stapling: macrocyclization for increased protein conformational stability and resistance to proteolysis Q Xiao, DS Ashton, ZB Jones, KP Thompson, JL Price RSC Chemical Biology, 2020 | 8 | 2020 |
Discovery of novel 2, 4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation Q Yan, Y Chen, B Tang, Q Xiao, R Qu, L Tong, J Liu, J Ding, Y Chen, ... European journal of medicinal chemistry 152, 298-306, 2018 | 8 | 2018 |
Total synthesis of leontopodioside A S Yan, Y Zhu, Y Wang, Q Xiao, N Ding, Y Li Tetrahedron Letters, 151886, 2020 | 4 | 2020 |
PEGylation near a Patch of Nonpolar Surface Residues Increases the Conformational Stability of the WW Domain SRE Draper, DS Ashton, BM Conover, AJ Carter, KL Stern, Q Xiao, ... The Journal of Organic Chemistry 85 (3), 1725-1730, 2019 | 2 | 2019 |
Structural Guidelines for Stabilization of α-Helical Coiled Coils via PEG Stapling Q Xiao, ZB Jones, SC Hatfield, DS Ashton, NA Dalley, CD Dyer, JL Price RSC Chemical Biology, 2022 | | 2022 |
Chemical Biology Q Xiao, ZB Jones, SC Hatfield, DS Ashton, NA Dalley, CD Dyer, ... | | |