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Qiang Xiao
Qiang Xiao
Verified email at scripps.edu
Title
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Cited by
Year
Discovery of 5-(methylthio) pyrimidine derivatives as L858R/T790M mutant selective epidermal growth factor receptor (EGFR) inhibitors
Q Xiao, R Qu, D Gao, Q Yan, L Tong, W Zhang, J Ding, H Xie, Y Li
Bioorganic & medicinal chemistry 24 (12), 2673-2680, 2016
212016
Semi-synthesis of a series natural flavonoids and flavonoid glycosides from scutellarin
S Yan, M Xie, Y Wang, Q Xiao, N Ding, Y Li
Tetrahedron 76 (8), 130950, 2020
202020
Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors
D Gao, N Jin, Y Fu, Y Zhu, Y Wang, T Wang, Y Chen, M Zhang, Q Xiao, ...
European Journal of Medicinal Chemistry, 113333, 2021
162021
Design, synthesis and biological evaluation of benzyloxyphenyl-methylaminophenol derivatives as STAT3 signaling pathway inhibitors
D Gao, Q Xiao, M Zhang, Y Li
Bioorganic & medicinal chemistry 24 (11), 2549-2558, 2016
152016
Stapling of two PEGylated side chains increases the conformational stability of the WW domain via an entropic effect
Q Xiao, NA Bécar, NP Brown, MS Smith, KL Stern, SRE Draper, ...
Organic & biomolecular chemistry 16 (46), 8933-8939, 2018
142018
Polyethylene Glycol Based Changes to β-Sheet Protein Conformational and Proteolytic Stability Depend on Conjugation Strategy and Location
SRE Draper, PB Lawrence, WM Billings, Q Xiao, NP Brown, NA Bécar, ...
Bioconjugate chemistry 28 (10), 2507-2513, 2017
122017
Influence of PEGylation on the strength of protein surface salt bridges
Q Xiao, SRE Draper, MS Smith, N Brown, NAB Pugmire, DS Ashton, ...
ACS chemical biology, 2019
102019
Long-range PEG stapling: macrocyclization for increased protein conformational stability and resistance to proteolysis
Q Xiao, DS Ashton, ZB Jones, KP Thompson, JL Price
RSC Chemical Biology, 2020
82020
Discovery of novel 2, 4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation
Q Yan, Y Chen, B Tang, Q Xiao, R Qu, L Tong, J Liu, J Ding, Y Chen, ...
European journal of medicinal chemistry 152, 298-306, 2018
82018
Total synthesis of leontopodioside A
S Yan, Y Zhu, Y Wang, Q Xiao, N Ding, Y Li
Tetrahedron Letters, 151886, 2020
42020
PEGylation near a Patch of Nonpolar Surface Residues Increases the Conformational Stability of the WW Domain
SRE Draper, DS Ashton, BM Conover, AJ Carter, KL Stern, Q Xiao, ...
The Journal of Organic Chemistry 85 (3), 1725-1730, 2019
22019
Structural Guidelines for Stabilization of α-Helical Coiled Coils via PEG Stapling
Q Xiao, ZB Jones, SC Hatfield, DS Ashton, NA Dalley, CD Dyer, JL Price
RSC Chemical Biology, 2022
2022
Chemical Biology
Q Xiao, ZB Jones, SC Hatfield, DS Ashton, NA Dalley, CD Dyer, ...
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Articles 1–13