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Lucy Lin
Lucy Lin
Verified email at scripps.edu
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Year
Blood-brain barrier-penetrating amphiphilic polymer nanoparticles deliver docetaxel for the treatment of brain metastases of triple negative breast cancer
C He, P Cai, J Li, T Zhang, L Lin, AZ Abbasi, JT Henderson, AM Rauth, ...
Journal of Controlled Release 246, 98-109, 2017
1012017
Coordinating biointeraction and bioreaction of a nanocarrier material and an anticancer drug to overcome membrane rigidity and target mitochondria in multidrug‐resistant cancer …
RX Zhang, LY Li, J Li, Z Xu, AZ Abbasi, L Lin, MA Amini, WY Weng, Y Sun, ...
Advanced Functional Materials 27 (39), 1700804, 2017
382017
Strategies to counteract botulinum neurotoxin A: nature’s deadliest biomolecule
L Lin, ME Olson, LM Eubanks, KD Janda
Accounts of chemical research 52 (8), 2322-2331, 2019
292019
A chemically contiguous hapten approach for a heroin–fentanyl vaccine
Y Natori, CS Hwang, L Lin, LC Smith, B Zhou, KD Janda
Beilstein Journal of Organic Chemistry 15 (1), 1020-1031, 2019
242019
Lateral flow assessment and unanticipated toxicity of kratom
LC Smith, L Lin, CS Hwang, B Zhou, DM Kubitz, H Wang, KD Janda
Chemical research in toxicology 32 (1), 113-121, 2018
212018
Catch and anchor approach to combat both toxicity and longevity of botulinum toxin A
L Lin, ME Olson, T Sugane, LD Turner, MA Tararina, AL Nielsen, ...
Journal of medicinal chemistry 63 (19), 11100-11120, 2020
182020
ssDNA nanotubes for selective targeting of glioblastoma and delivery of doxorubicin for enhanced survival
MA Harris, H Kuang, Z Schneiderman, ML Shiao, AT Crane, MR Chrostek, ...
Science Advances 7 (49), eabl5872, 2021
132021
Irreversible inhibition of BoNT/A protease: proximity-driven reactivity contingent upon a bifunctional approach
LD Turner, AL Nielsen, L Lin, S Pellett, T Sugane, ME Olson, EA Johnson, ...
RSC medicinal chemistry 12 (6), 960-969, 2021
102021
Identification of 3-hydroxy-1, 2-dimethylpyridine-4 (1 H)-thione as a metal-binding motif for the inhibition of botulinum neurotoxin A
L Lin, LD Turner, P Šilhár, S Pellett, EA Johnson, KD Janda
RSC Medicinal Chemistry 12 (1), 137-143, 2021
52021
Use of crystallography and molecular modeling for the inhibition of the botulinum neurotoxin A protease
LD Turner, AL Nielsen, L Lin, AJ Campedelli, NR Silvaggi, JS Chen, ...
ACS Medicinal Chemistry Letters 12 (8), 1318-1324, 2021
32021
Transformation of a Metal Chelate into a “Catch and Anchor” Inhibitor of Botulinum A Protease
L Lin, EN Patel, AL Nielsen, LD Turner, WH Tepp, K Nguyen, S Pellett, ...
International Journal of Molecular Sciences 24 (5), 4303, 2023
22023
Investigation of Salicylanilides as Botulinum Toxin Antagonists
EN Patel, L Lin, MM Sneller, LM Eubanks, WH Tepp, S Pellett, KD Janda
ACS infectious diseases 8 (8), 1637-1645, 2022
22022
Formation of ssDNA nanotubes from spherical micelles and their use as a delivery vehicle for chemotherapeutics and senolytics to triple negative breast cancer cells
L Lin, Z Schneiderman, A Venkatraman, E Kokkoli
Nanoscale 15 (22), 9801-9812, 2023
2023
Screening and Development of 9-Hydroxy-4H-Pyrido [1, 2-a] Pyrimidin-4-One–Based Bifunctional Inhibitors of BoNT-A/LC
L Lin, E Patel, A Nielson, S Pellett, K Nguyen, K Janda
Toxicon 214, S36-S37, 2022
2022
ssDNA Nanotubes as a Targeted Drug Delivery Vehicle for Triple Negative Breast Cancer
L Lin
Johns Hopkins University, 2022
2022
Targeted Irreversible Inhibition of Botulinum Neurotoxin a Light Chain
L Lin
The Scripps Research Institute, 2022
2022
Irreversible inhibition of BoNT/A protease: Unique warhead reactivity and function contingent upon a bifunctional approach
L Turner, AL Nielsen, L Lin, S Pellett, T Sugane, M Olsen, E Johnson
2021
Covalent inhibition of botulinum neurotoxin A–Exploration of warhead reactivity and function using a bifunctional approach
LD Turner, AL Nielsen, L Lin, S Pellett, T Sugane, ME Olson, KD Janda
Toxicon: official journal of the International Society on Toxinology 190 …, 2021
2021
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