Blood-brain barrier-penetrating amphiphilic polymer nanoparticles deliver docetaxel for the treatment of brain metastases of triple negative breast cancer C He, P Cai, J Li, T Zhang, L Lin, AZ Abbasi, JT Henderson, AM Rauth, ... Journal of Controlled Release 246, 98-109, 2017 | 101 | 2017 |
Coordinating biointeraction and bioreaction of a nanocarrier material and an anticancer drug to overcome membrane rigidity and target mitochondria in multidrug‐resistant cancer … RX Zhang, LY Li, J Li, Z Xu, AZ Abbasi, L Lin, MA Amini, WY Weng, Y Sun, ... Advanced Functional Materials 27 (39), 1700804, 2017 | 38 | 2017 |
Strategies to counteract botulinum neurotoxin A: nature’s deadliest biomolecule L Lin, ME Olson, LM Eubanks, KD Janda Accounts of chemical research 52 (8), 2322-2331, 2019 | 29 | 2019 |
A chemically contiguous hapten approach for a heroin–fentanyl vaccine Y Natori, CS Hwang, L Lin, LC Smith, B Zhou, KD Janda Beilstein Journal of Organic Chemistry 15 (1), 1020-1031, 2019 | 24 | 2019 |
Lateral flow assessment and unanticipated toxicity of kratom LC Smith, L Lin, CS Hwang, B Zhou, DM Kubitz, H Wang, KD Janda Chemical research in toxicology 32 (1), 113-121, 2018 | 21 | 2018 |
Catch and anchor approach to combat both toxicity and longevity of botulinum toxin A L Lin, ME Olson, T Sugane, LD Turner, MA Tararina, AL Nielsen, ... Journal of medicinal chemistry 63 (19), 11100-11120, 2020 | 18 | 2020 |
ssDNA nanotubes for selective targeting of glioblastoma and delivery of doxorubicin for enhanced survival MA Harris, H Kuang, Z Schneiderman, ML Shiao, AT Crane, MR Chrostek, ... Science Advances 7 (49), eabl5872, 2021 | 13 | 2021 |
Irreversible inhibition of BoNT/A protease: proximity-driven reactivity contingent upon a bifunctional approach LD Turner, AL Nielsen, L Lin, S Pellett, T Sugane, ME Olson, EA Johnson, ... RSC medicinal chemistry 12 (6), 960-969, 2021 | 10 | 2021 |
Identification of 3-hydroxy-1, 2-dimethylpyridine-4 (1 H)-thione as a metal-binding motif for the inhibition of botulinum neurotoxin A L Lin, LD Turner, P Šilhár, S Pellett, EA Johnson, KD Janda RSC Medicinal Chemistry 12 (1), 137-143, 2021 | 5 | 2021 |
Use of crystallography and molecular modeling for the inhibition of the botulinum neurotoxin A protease LD Turner, AL Nielsen, L Lin, AJ Campedelli, NR Silvaggi, JS Chen, ... ACS Medicinal Chemistry Letters 12 (8), 1318-1324, 2021 | 3 | 2021 |
Transformation of a Metal Chelate into a “Catch and Anchor” Inhibitor of Botulinum A Protease L Lin, EN Patel, AL Nielsen, LD Turner, WH Tepp, K Nguyen, S Pellett, ... International Journal of Molecular Sciences 24 (5), 4303, 2023 | 2 | 2023 |
Investigation of Salicylanilides as Botulinum Toxin Antagonists EN Patel, L Lin, MM Sneller, LM Eubanks, WH Tepp, S Pellett, KD Janda ACS infectious diseases 8 (8), 1637-1645, 2022 | 2 | 2022 |
Formation of ssDNA nanotubes from spherical micelles and their use as a delivery vehicle for chemotherapeutics and senolytics to triple negative breast cancer cells L Lin, Z Schneiderman, A Venkatraman, E Kokkoli Nanoscale 15 (22), 9801-9812, 2023 | | 2023 |
Screening and Development of 9-Hydroxy-4H-Pyrido [1, 2-a] Pyrimidin-4-One–Based Bifunctional Inhibitors of BoNT-A/LC L Lin, E Patel, A Nielson, S Pellett, K Nguyen, K Janda Toxicon 214, S36-S37, 2022 | | 2022 |
ssDNA Nanotubes as a Targeted Drug Delivery Vehicle for Triple Negative Breast Cancer L Lin Johns Hopkins University, 2022 | | 2022 |
Targeted Irreversible Inhibition of Botulinum Neurotoxin a Light Chain L Lin The Scripps Research Institute, 2022 | | 2022 |
Irreversible inhibition of BoNT/A protease: Unique warhead reactivity and function contingent upon a bifunctional approach L Turner, AL Nielsen, L Lin, S Pellett, T Sugane, M Olsen, E Johnson | | 2021 |
Covalent inhibition of botulinum neurotoxin A–Exploration of warhead reactivity and function using a bifunctional approach LD Turner, AL Nielsen, L Lin, S Pellett, T Sugane, ME Olson, KD Janda Toxicon: official journal of the International Society on Toxinology 190 …, 2021 | | 2021 |